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Protein

Cytochrome c oxidase assembly factor 5

Gene

COA5

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in an early step of the mitochondrial complex IV assembly process.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase assembly factor 5
Gene namesi
Name:COA5
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 11

Organism-specific databases

VGNCiVGNC:27544 COA5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003258751 – 74Cytochrome c oxidase assembly factor 5Add BLAST74

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 57PROSITE-ProRule annotation
Modified residuei37PhosphoserineBy similarity1
Disulfide bondi41 ↔ 47PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Phosphoprotein

Proteomic databases

PaxDbiQ3ZCK8

Expressioni

Gene expression databases

BgeeiENSBTAG00000014873

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000019802

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 65CHCHPROSITE-ProRule annotationAdd BLAST39

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi30 – 41Cx10C motifPROSITE-ProRule annotationAdd BLAST12
Motifi47 – 57Cx9C motifPROSITE-ProRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the PET191 family.Curated

Phylogenomic databases

eggNOGiKOG4114 Eukaryota
ENOG4111YIY LUCA
GeneTreeiENSGT00390000005548
HOVERGENiHBG107093
InParanoidiQ3ZCK8
KOiK18178
OMAiDMRSRFR
OrthoDBiEOG091G0ZD7
TreeFamiTF313953

Family and domain databases

InterProiView protein in InterPro
IPR018793 Cyt_c_oxidase_assmbl_Pet191
PANTHERiPTHR28627 PTHR28627, 1 hit
PfamiView protein in Pfam
PF10203 Pet191_N, 1 hit
PROSITEiView protein in PROSITE
PS51808 CHCH, 1 hit

Sequencei

Sequence statusi: Complete.

Q3ZCK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRYYEDKPE GGACAGVKED LGLCLLQSDC VLKEGKSPRQ CLKEGNCKAL
60 70
KYSFFECKRS MLDARSRFRG RKGY
Length:74
Mass (Da):8,417
Last modified:September 27, 2005 - v1
Checksum:iF763F3903025DD6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102104 mRNA Translation: AAI02105.1
RefSeqiNP_001181953.1, NM_001195024.2
UniGeneiBt.54038

Genome annotation databases

EnsembliENSBTAT00000019802; ENSBTAP00000019802; ENSBTAG00000014873
GeneIDi614794
KEGGibta:614794

Similar proteinsi

Entry informationi

Entry nameiCOA5_BOVIN
AccessioniPrimary (citable) accession number: Q3ZCK8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: September 27, 2005
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health