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Protein

Cytochrome c oxidase assembly factor 5

Gene

COA5

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in an early step of the mitochondrial complex IV assembly process.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase assembly factor 5
Gene namesi
Name:COA5
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 11

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003258751 – 74Cytochrome c oxidase assembly factor 5Add BLAST74

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 57PROSITE-ProRule annotation
Modified residuei37PhosphoserineBy similarity1
Disulfide bondi41 ↔ 47PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Phosphoprotein

Proteomic databases

PaxDbiQ3ZCK8.

Expressioni

Gene expression databases

BgeeiENSBTAG00000014873.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000019802.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 65CHCHPROSITE-ProRule annotationAdd BLAST39

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi30 – 41Cx10C motifPROSITE-ProRule annotationAdd BLAST12
Motifi47 – 57Cx9C motifPROSITE-ProRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the PET191 family.Curated

Phylogenomic databases

eggNOGiKOG4114. Eukaryota.
ENOG4111YIY. LUCA.
GeneTreeiENSGT00390000005548.
HOVERGENiHBG107093.
InParanoidiQ3ZCK8.
KOiK18178.
OMAiDMRSRFR.
OrthoDBiEOG091G0ZD7.
TreeFamiTF313953.

Family and domain databases

InterProiView protein in InterPro
IPR018793. Cyt_c_oxidase_assmbl_Pet191.
PfamiView protein in Pfam
PF10203. Pet191_N. 1 hit.
PROSITEiView protein in PROSITE
PS51808. CHCH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3ZCK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRYYEDKPE GGACAGVKED LGLCLLQSDC VLKEGKSPRQ CLKEGNCKAL
60 70
KYSFFECKRS MLDARSRFRG RKGY
Length:74
Mass (Da):8,417
Last modified:September 27, 2005 - v1
Checksum:iF763F3903025DD6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102104 mRNA. Translation: AAI02105.1.
RefSeqiNP_001181953.1. NM_001195024.2.
UniGeneiBt.54038.

Genome annotation databases

EnsembliENSBTAT00000019802; ENSBTAP00000019802; ENSBTAG00000014873.
GeneIDi614794.
KEGGibta:614794.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102104 mRNA. Translation: AAI02105.1.
RefSeqiNP_001181953.1. NM_001195024.2.
UniGeneiBt.54038.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000019802.

Proteomic databases

PaxDbiQ3ZCK8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000019802; ENSBTAP00000019802; ENSBTAG00000014873.
GeneIDi614794.
KEGGibta:614794.

Organism-specific databases

CTDi493753.

Phylogenomic databases

eggNOGiKOG4114. Eukaryota.
ENOG4111YIY. LUCA.
GeneTreeiENSGT00390000005548.
HOVERGENiHBG107093.
InParanoidiQ3ZCK8.
KOiK18178.
OMAiDMRSRFR.
OrthoDBiEOG091G0ZD7.
TreeFamiTF313953.

Gene expression databases

BgeeiENSBTAG00000014873.

Family and domain databases

InterProiView protein in InterPro
IPR018793. Cyt_c_oxidase_assmbl_Pet191.
PfamiView protein in Pfam
PF10203. Pet191_N. 1 hit.
PROSITEiView protein in PROSITE
PS51808. CHCH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOA5_BOVIN
AccessioniPrimary (citable) accession number: Q3ZCK8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: September 27, 2005
Last modified: June 7, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.