Q3ZBS9 (NNAT_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Neuronatin

Gene names

Name:

NNAT

Organism

Bos taurus (Bovine) [Reference proteome]

Taxonomic identifier

9913 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	81 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels By similarity.
Sequence similarities	Belongs to the neuronatin family.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Molecular function	Developmental protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	brain development Inferred from electronic annotation. Source: InterPro positive regulation of insulin secretion Inferred from electronic annotation. Source: Compara regulation of protein localization Inferred from electronic annotation. Source: Compara response to glucose stimulus Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform Alpha (identifier: Q3ZBS9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform Beta (identifier: Q3ZBS9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     25-51: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 81	81	Neuronatin		PRO_0000289055
Natural variations
	Alternative sequence	25 – 51	27	Missing in isoform Beta.		VSP_025881

Sequences

	Sequence		Length	Mass (Da)
	Isoform Alpha [UniParc]. Last modified September 27, 2005. Version 1. Checksum: 067086D85B3E3D20	FASTA	81	9,246
	10 20 30 40 50 60 MAAVAAASAE LLIIGWYIFR VLLQVFLECC IYWVGFAFRN PPGTQPIARS EVFRYSLQKL 70 80 AYTVSRTGRH VLGERRQRAP N
	Isoform Beta [UniParc]. Checksum: 184E7C897F006C87	FASTA	54	6,162
	10 20 30 40 50 MAAVAAASAE LLIIGWYIFR VLLQVFRYSL QKLAYTVSRT GRHVLGERRQ RAPN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Mammalian Gene Collection (MGC) project Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA). Strain: Hereford. Tissue: Fetal liver.
[2]	"Bos taurus neuronatin beta." Hahn Y., Chung J.H. Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA).
[3]	"Analysis of imprinted messenger RNA expression during bovine preimplantation development." Ruddock N.T., Wilson K.J., Cooney M.A., Korfiatis N.A., Tecirlioglu R.T., French A.J. Biol. Reprod. 70:1131-1135(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 14-81 (ISOFORM ALPHA).

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC103128 mRNA. Translation: AAI03129.1. AB047030 mRNA. Translation: BAB08220.1. AY360450 mRNA. Translation: AAR12962.1.
IPI	IPI00687366. IPI00711793.
RefSeq	NP_001188253.1. NM_001201324.1. NP_847893.1. NM_178323.3.
UniGene	Bt.11341.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	9913.ENSBTAP00000004170.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSBTAT00000004170; ENSBTAP00000004170; ENSBTAG00000003212. ENSBTAT00000004171; ENSBTAP00000004171; ENSBTAG00000003212.
GeneID	353114.
KEGG	bta:353114.
Organism-specific databases
CTD	4826.
Phylogenomic databases
eggNOG	NOG45532.
GeneTree	ENSGT00390000007412.
HOGENOM	HOG000113807.
HOVERGEN	HBG001605.
InParanoid	Q3ZBS9.
OMA	MGERRQR.
OrthoDB	EOG4M91T5.
Family and domain databases
InterPro	IPR024885. Neuronatin. [Graphical view]
PANTHER	PTHR15285. PTHR15285. 1 hit.
ProtoNet	Search...
Other
NextBio	20812698.

Entry information

Entry name

NNAT_BOVIN

Accession

Primary (citable) accession number: Q3ZBS9
Secondary accession number(s): Q6UTX8, Q9GMZ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	September 27, 2005
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program