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Q3ZB30

- Q3ZB30_MOUSE

UniProt

Q3ZB30 - Q3ZB30_MOUSE

Protein
Submitted name:

Hrh2 protein

Gene

Hrh2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (27 Sep 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. histamine receptor activity Source: InterPro

    GO - Biological processi

    1. digestive tract development Source: MGI
    2. epithelial cell morphogenesis Source: MGI
    3. gastric acid secretion Source: MGI
    4. gastrin-induced gastric acid secretion Source: MGI
    5. gland development Source: MGI
    6. histamine-induced gastric acid secretion Source: MGI
    7. memory Source: MGI
    8. positive regulation of vasoconstriction Source: InterPro
    9. regulation of synaptic plasticity Source: MGI
    10. visual learning Source: MGI

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Hrh2 proteinImported
    Gene namesi
    Name:Hrh2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:108482. Hrh2.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriQ3ZB30.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    HOVERGENiHBG106962.
    InParanoidiQ3ZB30.
    KOiK04150.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000503. Histamine_H2_rcpt.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00531. HISTAMINEH2R.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3ZB30-1 [UniParc]FASTAAdd to Basket

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    EPNGTVHSCC LDSIALKVTI SVVLTTLIFI TVAGNVVVCL AVSLNRRLRS    50
    LTNCFIVSLA ATDLLLGLLV MPFSAIYQLS FKWSFGQVFC NIYTSLDVML 100
    CTASILNLFM ISLDRYCAVT DPLRYPVLVT PVRVAISLVF IWVISITLSF 150
    LSIHLGWNSR NGTRGGNDTF KCKVQVNEVY GLVDGMVTFY LPLLIMCVTY 200
    YRIFKIAREQ AKRINHISSW KAATIREHKA TVTLAAVMGA FIVCWFPYFT 250
    AFVYRGLRGD DAVNEVVEGI VLWLGYANSA LNPILYATLN RDFRMAYQQL 300
    FHCKLASHNS HKTSLRLNNS LLSRSQSREG RWQEEKPLKL QVWSGTELTH 350
    PQGSPVR 357
    Length:357
    Mass (Da):40,153
    Last modified:September 27, 2005 - v1
    Checksum:i6F128006616957AC
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC103553 mRNA. Translation: AAI03554.1.
    BC103554 mRNA. Translation: AAI03555.1.
    RefSeqiNP_032312.2. NM_008286.2.
    UniGeneiMm.57243.

    Genome annotation databases

    GeneIDi15466.
    KEGGimmu:15466.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC103553 mRNA. Translation: AAI03554.1 .
    BC103554 mRNA. Translation: AAI03555.1 .
    RefSeqi NP_032312.2. NM_008286.2.
    UniGenei Mm.57243.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    DNASUi 15466.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 15466.
    KEGGi mmu:15466.

    Organism-specific databases

    CTDi 3274.
    MGIi MGI:108482. Hrh2.

    Phylogenomic databases

    HOVERGENi HBG106962.
    InParanoidi Q3ZB30.
    KOi K04150.

    Miscellaneous databases

    NextBioi 288294.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q3ZB30.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000503. Histamine_H2_rcpt.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00531. HISTAMINEH2R.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: PCR rescued clonesImported.

    Entry informationi

    Entry nameiQ3ZB30_MOUSE
    AccessioniPrimary (citable) accession number: Q3ZB30
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 27, 2005
    Last sequence update: September 27, 2005
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)