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Q3ZB30

- Q3ZB30_MOUSE

UniProt

Q3ZB30 - Q3ZB30_MOUSE

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Protein
Submitted name:

Hrh2 protein

Gene

Hrh2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. histamine receptor activity Source: InterPro

GO - Biological processi

  1. digestive tract development Source: MGI
  2. epithelial cell morphogenesis Source: MGI
  3. gastric acid secretion Source: MGI
  4. gastrin-induced gastric acid secretion Source: MGI
  5. gland development Source: MGI
  6. histamine-induced gastric acid secretion Source: MGI
  7. memory Source: MGI
  8. positive regulation of vasoconstriction Source: InterPro
  9. regulation of synaptic plasticity Source: MGI
  10. toxin transport Source: MGI
  11. visual learning Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiREACT_242871. G alpha (s) signalling events.
REACT_257161. Histamine receptors.

Names & Taxonomyi

Protein namesi
Submitted name:
Hrh2 proteinImported
Gene namesi
Name:Hrh2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:108482. Hrh2.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevestigatoriQ3ZB30.

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOVERGENiHBG106962.
KOiK04150.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000503. Histamine_H2_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00531. HISTAMINEH2R.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3ZB30-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
EPNGTVHSCC LDSIALKVTI SVVLTTLIFI TVAGNVVVCL AVSLNRRLRS
60 70 80 90 100
LTNCFIVSLA ATDLLLGLLV MPFSAIYQLS FKWSFGQVFC NIYTSLDVML
110 120 130 140 150
CTASILNLFM ISLDRYCAVT DPLRYPVLVT PVRVAISLVF IWVISITLSF
160 170 180 190 200
LSIHLGWNSR NGTRGGNDTF KCKVQVNEVY GLVDGMVTFY LPLLIMCVTY
210 220 230 240 250
YRIFKIAREQ AKRINHISSW KAATIREHKA TVTLAAVMGA FIVCWFPYFT
260 270 280 290 300
AFVYRGLRGD DAVNEVVEGI VLWLGYANSA LNPILYATLN RDFRMAYQQL
310 320 330 340 350
FHCKLASHNS HKTSLRLNNS LLSRSQSREG RWQEEKPLKL QVWSGTELTH

PQGSPVR
Length:357
Mass (Da):40,153
Last modified:September 27, 2005 - v1
Checksum:i6F128006616957AC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103553 mRNA. Translation: AAI03554.1.
BC103554 mRNA. Translation: AAI03555.1.
RefSeqiNP_032312.2. NM_008286.2.
UniGeneiMm.57243.

Genome annotation databases

GeneIDi15466.
KEGGimmu:15466.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103553 mRNA. Translation: AAI03554.1 .
BC103554 mRNA. Translation: AAI03555.1 .
RefSeqi NP_032312.2. NM_008286.2.
UniGenei Mm.57243.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

DNASUi 15466.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 15466.
KEGGi mmu:15466.

Organism-specific databases

CTDi 3274.
MGIi MGI:108482. Hrh2.

Phylogenomic databases

HOVERGENi HBG106962.
KOi K04150.

Enzyme and pathway databases

Reactomei REACT_242871. G alpha (s) signalling events.
REACT_257161. Histamine receptors.

Miscellaneous databases

NextBioi 288294.
SOURCEi Search...

Gene expression databases

Genevestigatori Q3ZB30.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000503. Histamine_H2_rcpt.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR00531. HISTAMINEH2R.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.

Entry informationi

Entry nameiQ3ZB30_MOUSE
AccessioniPrimary (citable) accession number: Q3ZB30
Entry historyi
Integrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: November 26, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)