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Protein

Protein Wnt

Gene

Wnt4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinUniRule annotationSAAS annotation
Biological processWnt signaling pathwayUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:Wnt4Imported
ORF Names:mCG_9329Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98957. Wnt4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Secreted

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000036856.

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3913. Eukaryota.
ENOG410XQZ1. LUCA.
HOVERGENiHBG001595.
KOiK00408.
OMAiNSQFKPH.
OrthoDBiEOG091G0OFF.

Family and domain databases

InterProiView protein in InterPro
IPR005817. Wnt.
IPR009142. Wnt4.
IPR018161. Wnt_CS.
PANTHERiPTHR12027. PTHR12027. 1 hit.
PfamiView protein in Pfam
PF00110. wnt. 1 hit.
PRINTSiPR01844. WNT4PROTEIN.
PR01349. WNTPROTEIN.
SMARTiView protein in SMART
SM00097. WNT1. 1 hit.
PROSITEiView protein in PROSITE
PS00246. WNT1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3ZB23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPRSCLRSL RLLVFAVFSA AASNWLYLAK LSSVGSISEE ETCEKLKGLI
60 70 80 90 100
QRQVQMCKRN LEVMDSVRRG AQLAIEECQY QFRNRRWNCS TLDSLPVFGK
110 120 130 140 150
VVTQGTREAA FVYAISSAGV AFAVTRACSS GELEKCGCDR TVHGVSPQGF
160 170 180 190 200
QWSGCSDNIA YGVAFSQSFV DVRERSKGAS SSRALMNLHN NEAGRKAILT
210 220 230 240 250
HMRVECKCHG VSGSCEVKTC WRAVPPFRQV GHALKEKFDG ATEVEPRRVG
260 270 280 290 300
SSRALVPRNA QFKPHTDEDL VYLEPSPDFC EQDIRSGVLG TRGRTCNKTS
310 320 330 340 350
KAIDGCELLC CGRGFHTAQV ELAERCGCRF HWCCFVKCRQ CQRLVEMHTC

R
Length:351
Mass (Da):39,050
Last modified:September 27, 2005 - v1
Checksum:i7E1C5C739BE939D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC101962 mRNA. Translation: AAI01963.1.
BC103560 mRNA. Translation: AAI03561.1.
BC103561 mRNA. Translation: AAI03562.1.
BC103562 mRNA. Translation: AAI03563.1.
CH466552 Genomic DNA. Translation: EDL29922.1.
RefSeqiNP_033549.1. NM_009523.2.
UniGeneiMm.20355.

Genome annotation databases

GeneIDi22417.
KEGGimmu:22417.

Similar proteinsi

Entry informationi

Entry nameiQ3ZB23_MOUSE
AccessioniPrimary (citable) accession number: Q3ZB23
Entry historyiIntegrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: October 25, 2017
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)