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Protein
Submitted name:

C-C motif chemokine receptor 8

Gene

Ccr8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
C-C motif chemokine receptor 8Imported
Submitted name:
Chemokine (C-C motif) receptor 8Imported
Gene namesi
Name:Ccr8Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1201402. Ccr8.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 59HelicalSequence analysisAdd BLAST26
Transmembranei71 – 89HelicalSequence analysisAdd BLAST19
Transmembranei109 – 127HelicalSequence analysisAdd BLAST19
Transmembranei147 – 170HelicalSequence analysisAdd BLAST24
Transmembranei200 – 217HelicalSequence analysisAdd BLAST18
Transmembranei237 – 258HelicalSequence analysisAdd BLAST22
Transmembranei278 – 301HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000042262.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000038473.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 298G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST249

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IJ9D. Eukaryota.
ENOG410YUBT. LUCA.
HOVERGENiHBG106917.
KOiK04183.
OMAiMCKIMAG.
OrthoDBiEOG091G0HEN.

Family and domain databases

InterProiIPR004068. Chemokine_CCR8.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01530. CHEMOKINER8.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3ZB17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYTMEPNVT MTDYYPDFFT APCDAEFLLR GSMLYLAILY CVLFVLGLLG
60 70 80 90 100
NSLVILVLVG CKKLRSITDI YLLNLAASDL LFVLSIPFQT HNLLDQWVFG
110 120 130 140 150
TAMCKVVSGL YYIGFFSSMF FITLMSVDRY LAIVHAVYAI KVRTASVGTA
160 170 180 190 200
LSLTVWLAAV TATIPLMVFY QVASEDGMLQ CFQFYEEQSL RWKLFTHFEI
210 220 230 240 250
NALGLLLPFA ILLFCYVRIL QQLRGCLNHN RTRAIKLVLT VVIVSLLFWV
260 270 280 290 300
PFNVALFLTS LHDLHILDGC ATRQRLALAI HVTEVISFTH CCVNPVIYAF
310 320 330 340 350
IGEKFKKHLM DVFQKSCSHI FLYLGRQMPV GALERQLSSN QRSSHSSTLD

DIL
Length:353
Mass (Da):40,045
Last modified:September 27, 2005 - v1
Checksum:i31EC4B642CDB9AE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC101966 mRNA. Translation: AAI01967.1.
BC101967 mRNA. Translation: AAI01968.1.
BC103566 mRNA. Translation: AAI03567.1.
BC103567 mRNA. Translation: AAI03568.1.
DQ360291 Genomic DNA. Translation: ABC95971.1.
RefSeqiNP_031746.1. NM_007720.2.
UniGeneiMm.442098.

Genome annotation databases

GeneIDi12776.
KEGGimmu:12776.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC101966 mRNA. Translation: AAI01967.1.
BC101967 mRNA. Translation: AAI01968.1.
BC103566 mRNA. Translation: AAI03567.1.
BC103567 mRNA. Translation: AAI03568.1.
DQ360291 Genomic DNA. Translation: ABC95971.1.
RefSeqiNP_031746.1. NM_007720.2.
UniGeneiMm.442098.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000038473.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12776.
KEGGimmu:12776.

Organism-specific databases

CTDi1237.
MGIiMGI:1201402. Ccr8.

Phylogenomic databases

eggNOGiENOG410IJ9D. Eukaryota.
ENOG410YUBT. LUCA.
HOVERGENiHBG106917.
KOiK04183.
OMAiMCKIMAG.
OrthoDBiEOG091G0HEN.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000042262.

Family and domain databases

InterProiIPR004068. Chemokine_CCR8.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00657. CCCHEMOKINER.
PR01530. CHEMOKINER8.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3ZB17_MOUSE
AccessioniPrimary (citable) accession number: Q3ZB17
Entry historyi
Integrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: November 30, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.