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Protein
Submitted name:

Cytochrome P450, family 19, subfamily a, polypeptide 1

Gene

Cyp19a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 19, subfamily a, polypeptide 1Imported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Cyp19a1Imported
ORF Names:mCG_7170Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88587. Cyp19a1.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000032274.
ExpressionAtlasiQ3ZAT3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034811.

Structurei

3D structure databases

SMRiQ3ZAT3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
HOVERGENiHBG050750.
KOiK07434.
OMAiMRRIMLD.
OrthoDBiEOG091G056R.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3ZAT3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLEMLNPMQ YNVTIMVPET VTVSAMPLLL IMGLLLLIWN CESSSSIPGP
60 70 80 90 100
GYCLGIGPLI SHGRFLWMGI GSACNYYNKM YGEFMRVWIS GEETLIISKS
110 120 130 140 150
SSMFHVMKHS HYISRFGSKR GLQCIGMHEN GIIFNNNPSL WRTIRPFFMK
160 170 180 190 200
ALTGPGLVRM VEVCVESIKQ HLDRLGEVTD TSGYVDVLTL MRHIMLDTSN
210 220 230 240 250
MLFLGIPLDE SAIVKKIQGY FNAWQALLIK PNIFFKISWL YRKYERSVKD
260 270 280 290 300
LKDEIAVLVE KKRHKVSTAE KLEDCMDFAT DLIFAERRGD LTKENVNQCI
310 320 330 340 350
LEMLIAAPDT MSVTLYFMLL LVAEYPEVEA AILKEIHTVV GDRDIKIEDI
360 370 380 390 400
QNLKVVENFI NESMRYQPVV DLVMRRALED DVIDGYPVKK GTNIILNIGR
410 420 430 440 450
MHRLEYFPKP NEFTLENFEK NVPYRYFQPF GFGPRGCAGK YIAMVMMKVV
460 470 480 490 500
LVTLLRRFQV KTLQKRCIEN IPKKNDLSLH PNEDRHLVEI IFSPRNSDKY

LQQ
Length:503
Mass (Da):58,015
Last modified:September 27, 2005 - v1
Checksum:i737400389D1AEFF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103670 mRNA. Translation: AAI03671.1.
BC104489 mRNA. Translation: AAI04490.1.
AK143323 mRNA. Translation: BAE25342.1.
CH466522 Genomic DNA. Translation: EDL25809.1.
RefSeqiNP_031836.1. NM_007810.4.
UniGeneiMm.478781.
Mm.5199.

Genome annotation databases

GeneIDi13075.
KEGGimmu:13075.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC103670 mRNA. Translation: AAI03671.1.
BC104489 mRNA. Translation: AAI04490.1.
AK143323 mRNA. Translation: BAE25342.1.
CH466522 Genomic DNA. Translation: EDL25809.1.
RefSeqiNP_031836.1. NM_007810.4.
UniGeneiMm.478781.
Mm.5199.

3D structure databases

SMRiQ3ZAT3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034811.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi13075.
KEGGimmu:13075.

Organism-specific databases

CTDi1588.
MGIiMGI:88587. Cyp19a1.

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
HOVERGENiHBG050750.
KOiK07434.
OMAiMRRIMLD.
OrthoDBiEOG091G056R.

Miscellaneous databases

ChiTaRSiCyp19a1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000032274.
ExpressionAtlasiQ3ZAT3. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3ZAT3_MOUSE
AccessioniPrimary (citable) accession number: Q3ZAT3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: March 15, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.