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Q3Z997 (PPNK_DEHE1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase

Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23
Gene names
Name:ppnK
Ordered Locus Names:DET0458
OrganismDehalococcoides ethenogenes (strain 195) [Complete proteome] [HAMAP]
Taxonomic identifier243164 [NCBI]
Taxonomic lineageBacteriaChloroflexiDehalococcoidiaDehalococcoidalesDehalococcoidaceaeDehalococcoides

Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processNAD metabolic process

Inferred from electronic annotation. Source: InterPro

NADP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Probable inorganic polyphosphate/ATP-NAD kinase HAMAP-Rule MF_00361
PRO_0000229630

Sequences

Sequence LengthMass (Da)Tools
Q3Z997 [UniParc].

Last modified September 27, 2005. Version 1.
Checksum: C0A931122B4590D8

FASTA28431,025
        10         20         30         40         50         60 
MYKKIGIIYH PLNPAACELA VRLAAKLDSL GIENWSDSAW QADKLASKIQ NTQLIVTTGG 

        70         80         90        100        110        120 
DGTILRTAHA ILPHEIPILS INLGKVGFMT ELSPEDAILG LEKVLAGNGW IDERNLLEAE 

       130        140        150        160        170        180 
YLPHNSAPAR QFFIMNDAVV ARGQIARVIC VSVDINSHPF TTYKADGAIV STATGSTGYS 

       190        200        210        220        230        240 
YAAGGPVLQP NSADIILTPI LPHLGRGYSL VLPADSTIDL KVNTWHEATL SIDGFINMPV 

       250        260        270        280 
SSGDILRLRR SAKKINFIRL RPDNYFYKEL DTKLKGNNES VYDR 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000027 Genomic DNA. Translation: AAW40221.1.
RefSeqYP_181202.1. NC_002936.3.

3D structure databases

ProteinModelPortalQ3Z997.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243164.DET0458.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW40221; AAW40221; DET0458.
GeneID3230185.
KEGGdet:DET0458.
PATRIC21607985. VBIDehEth89364_0436.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0061.
HOGENOMHOG000227222.
KOK00858.
OMALEIHKKS.
OrthoDBEOG6PZXDR.
ProtClustDBCLSK2767674.

Enzyme and pathway databases

BioCycDETH243164:GJNF-458-MONOMER.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK_prd.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK_DEHE1
AccessionPrimary (citable) accession number: Q3Z997
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: September 27, 2005
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families