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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195) (Dehalococcoides ethenogenes (strain 195))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciDMCC243164:G1G45-581-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:DET0595
OrganismiDehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195) (Dehalococcoides ethenogenes (strain 195))
Taxonomic identifieri243164 [NCBI]
Taxonomic lineageiBacteriaChloroflexiDehalococcoidiaDehalococcoidalesDehalococcoidaceaeDehalococcoides
Proteomesi
  • UP000008289 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002640291 – 189Peptidyl-tRNA hydrolaseAdd BLAST189

Proteomic databases

PRIDEiQ3Z8W2

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi243164.DET0595

Structurei

3D structure databases

ProteinModelPortaliQ3Z8W2
SMRiQ3Z8W2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit

Sequencei

Sequence statusi: Complete.

Q3Z8W2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLIIGLGNP GKEYSGNRHN VGFQCLSRFA KDNHISFDKK CCLSRTGSGR
60 70 80 90 100
INDEEIVLAK PQTYMNLSGK AASQLLRRYN LKAADIIVVQ DDLDLPAGKI
110 120 130 140 150
RLRLGGSAGG HNGISSIITD IGTKEFIRLK IGIGKPDSRN NGTEVVDHVL
160 170 180
GNFGGEEREI MDKAITRASE ALTCLLTFGL DTASNRFNS
Length:189
Mass (Da):20,521
Last modified:September 27, 2005 - v1
Checksum:i4AFD67E0A4AAE18D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000027 Genomic DNA Translation: AAW40112.1
RefSeqiWP_010936370.1, NC_002936.3

Genome annotation databases

EnsemblBacteriaiAAW40112; AAW40112; DET0595
GeneIDi3230075
KEGGidet:DET0595
PATRICifig|243164.10.peg.573

Similar proteinsi

Entry informationi

Entry nameiPTH_DEHM1
AccessioniPrimary (citable) accession number: Q3Z8W2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 27, 2005
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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