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Q3Z745 (Q3Z745_DEHE1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401
Gene names
Name:msrA HAMAP MF_01401 EMBL AAW39515.1
Ordered Locus Names:DET1241
OrganismDehalococcoides ethenogenes (strain 195) [Complete proteome] [HAMAP]
Taxonomic identifier243164 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Dehalococcoidetes › Dehalococcoides

Protein attributes

Sequence length176 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site111 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
Q3Z745 [UniParc].

Last modified September 27, 2005. Version 1.
Checksum: 98F1D80A8D11F11A

FASTA17619,869
        10         20         30         40         50         60 
MTETAVFGGG CFWCMEAVFS RLSGVLKVEP GYAGGTLPNP TYQQVCAGDT GHAEVVKLEF 

        70         80         90        100        110        120 
DPALVSYTDL LDVFFQMHDP TTPNRQGQDI GTQYRSVIFY TTPAQKVQAE ETIKKLDESA 

       130        140        150        160        170 
GFPERIVTGV LPLEKFYPAE DYHRQYYALH SRQPYCRFVI QPKLDKLKEH FGGMQK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000027 Genomic DNA. Translation: AAW39515.1.
RefSeqYP_181954.1. NC_002936.3.

3D structure databases

ProteinModelPortalQ3Z745.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3Z745.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3229476.
GenomeReviewsGene locus DET1241 in contig CP000027_GR.
KEGGdet:DET1241.
NMPDRfig|243164.3.peg.1190.
PATRIC21609513. VBIDehEth89364_1172.
TIGRDET1241.

Phylogenomic databases

eggNOGCOG0225.
HOGENOMHBG748152.
OMAPYCRFVI.
PhylomeDBQ3Z745.
ProtClustDBCLSK837054.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3Z745_DEHE1
AccessionPrimary (citable) accession number: Q3Z745
Entry history
Integrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info