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Q3Z717 (SYR_DEHE1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:DET1270
OrganismDehalococcoides ethenogenes (strain 195) [Complete proteome] [HAMAP]
Taxonomic identifier243164 [NCBI]
Taxonomic lineageBacteriaChloroflexiDehalococcoidiaDehalococcoidalesDehalococcoidaceaeDehalococcoides

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242012

Regions

Motif133 – 14311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q3Z717 [UniParc].

Last modified September 27, 2005. Version 1.
Checksum: 543E53BA2F72AE14

FASTA55661,770
        10         20         30         40         50         60 
MNSILAIKNI IIESLSQALE KARQEGQIPA LSVDISIEHP QKTNYGDYAT SLPLRLAKAT 

        70         80         90        100        110        120 
GKRPMELAEI LAGYIEPGEG IAKVSVAPPG FINFTFSKEW LCNLVKTILG EAESYGNINM 

       130        140        150        160        170        180 
GGGSRVQIEF VSANPTGPIH IGHGRGAVLG STLSNVLKAA GYYVEEEFYI NDAGSQIDAF 

       190        200        210        220        230        240 
KRTLFARYQQ ALGKEAAVPQ DGYHGQYMVE LAAEMVAKYG DKYLQMPLEI AQNDLGEIGM 

       250        260        270        280        290        300 
ARMLCLISDD LKSLKVDFDV WFSERSLYSG GQYKTAMDIL LANNYIAERD NATWFSSTLL 

       310        320        330        340        350        360 
GDSKDNVIVR SDGTPTYFAS DIAYHYNKFI ERKFDRVINI WGADHQGHVS RMKAMLSALG 

       370        380        390        400        410        420 
INPERLTTLL FQMITLKRGG ELVRLSKRTG EMISLSEVIE EVGADACRFF FLSRSTESQM 

       430        440        450        460        470        480 
DFDLELAKKE SAENPVYYVQ YAHARICSIL SLAKEKGLSY SGGDTALLGE EAELELIRKM 

       490        500        510        520        530        540 
AELPEIVETV ARTLEPHHLT YYAQELANAF HQFYKDCRVI SDNTELSSAR LKLVDASRIV 

       550 
LARTLHLMGM TSPQSM 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000027 Genomic DNA. Translation: AAW39452.1.
RefSeqYP_181982.1. NC_002936.3.

3D structure databases

ProteinModelPortalQ3Z717.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243164.DET1270.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW39452; AAW39452; DET1270.
GeneID3229412.
KEGGdet:DET1270.
PATRIC21609567. VBIDehEth89364_1199.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycDETH243164:GJNF-1271-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_DEHE1
AccessionPrimary (citable) accession number: Q3Z717
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: September 27, 2005
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries