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Reviewed, UniProtKB/Swiss-Prot Q3Z6W5 (COAE_DEHE1)

Last modified June 16, 2009. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Dephospho-CoA kinase
    EC=2.7.1.24
Alternative name(s):
    Dephosphocoenzyme A kinase
Gene names
Name: coaE
Ordered Locus Names: DET1323
OrganismDehalococcoides ethenogenes (strain 195) [Complete proteome] [HAMAP]
Taxonomic identifier243164 [NCBI]
Taxonomic lineageBacteriaChloroflexiDehalococcoidetesDehalococcoides

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity.

Catalytic activity

ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP MF_00376

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme A from pantothenate: step 5/5. HAMAP MF_00376

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the coaE family.

Contains 1 DPCK (dephospho-CoA kinase) domain.

Ontologies

Keywords
   Biological processCoenzyme A biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcoenzyme A biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

dephospho-CoA kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Dephospho-CoA kinase HAMAP MF_00376
PRO_0000243280

Regions

Domain3 – 198196DPCK
Nucleotide binding8 – 158ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q3Z6W5-1 [UniParc].

Last modified September 27, 2005. Version 1.
Checksum: EA85547D8461591B

FASTA19822,320
        10         20         30         40         50         60 
MKIVGITGGI GSGKTTVCRY LKELGVNIID ADEIGHRVLQ NKGIRTRITD VFGNEVMNPD 

        70         80         90        100        110        120 
GSINRKILGE LVFGYPERLE HLNKITHPLI EQAIASLLEE YRQKGIKAVA IEAPLLVEAG 

       130        140        150        160        170        180 
WLKLVNEVWL ITAPKESIFK RLRNRMGLSR EQVMARIQSQ ATDNERLKYA SIVINNNCRF 

       190 
EDLKSCVQLL AKERLELA 

« Hide

Cross-references

Sequence databases

CP000027 Genomic DNA. Translation: AAW39462.1.
RefSeqYP_182034.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3229422.
GenomeReviewsGene locus DET1323 in contig CP000027_GR.
KEGGdet:DET1323.
NMPDRfig|243164.3.peg.487.
TIGRDET1323.

Phylogenomic databases

HOGENOMQ3Z6W5.
OMAQ3Z6W5. LHPMIRQ.

Enzyme and pathway databases

BioCycDETH243164:DET_1323-MON.

Family and domain databases

HAMAPMF_00376.
[Tree]
InterProIPR001977. Depp_CoAkinase.
[Graphical view]
PANTHERPTHR10695. Depp_CoAkinase. 1 hit.
PfamPF01121. CoaE. 1 hit.
[Graphical view]
ProDomPD003329. Depp_CoAkinase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00152. Depp_CoAkinase. 1 hit.
PROSITEPS51219. DPCK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOAE_DEHE1
AccessionPrimary (citable) accession number: Q3Z6W5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: September 27, 2005
Last modified: June 16, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents