ID   TRPF_DEHE1              Reviewed;         219 AA.
AC   Q3Z6G4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=N-(5'-phosphoribosyl)anthranilate isomerase;
DE            Short=PRAI;
DE            EC=5.3.1.24;
GN   Name=trpF; OrderedLocusNames=DET1485;
OS   Dehalococcoides ethenogenes (strain 195).
OC   Bacteria; Chloroflexi; Dehalococcoidetes; Dehalococcoides.
OX   NCBI_TaxID=243164;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15637277; DOI=10.1126/science.1102226;
RA   Seshadri R., Adrian L., Fouts D.E., Eisen J.A., Phillippy A.M.,
RA   Methe B.A., Ward N.L., Nelson W.C., DeBoy R.T., Khouri H.M.,
RA   Kolonay J.F., Dodson R.J., Daugherty S.C., Brinkac L.M.,
RA   Sullivan S.A., Madupu R., Nelson K.E., Kang K.H., Impraim M., Tran K.,
RA   Robinson J.M., Forberger H.A., Fraser C.M., Zinder S.H.,
RA   Heidelberg J.F.;
RT   "Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides
RT   ethenogenes.";
RL   Science 307:105-108(2005).
CC   -!- CATALYTIC ACTIVITY: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-
CC       (2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 3/5.
CC   -!- SIMILARITY: Belongs to the trpF family.
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DR   EMBL; CP000027; AAW39327.1; -; Genomic_DNA.
DR   RefSeq; YP_182185.1; -.
DR   GeneID; 3229285; -.
DR   GenomeReviews; CP000027_GR; DET1485.
DR   KEGG; det:DET1485; -.
DR   NMPDR; fig|243164.3.peg.1410; -.
DR   TIGR; DET1485; -.
DR   HOGENOM; Q3Z6G4; -.
DR   OMA; Q3Z6G4; SKICGIT.
DR   BioCyc; DETH243164:DET_1485-MON; -.
DR   GO; GO:0004640; F:phosphoribosylanthranilate isomerase activity; IEA:HAMAP.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00135; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001240; PRAI.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   Pfam; PF00697; PRAI; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; Isomerase; Tryptophan biosynthesis.
FT   CHAIN         1    219       N-(5'-phosphoribosyl)anthranilate
FT                                isomerase.
FT                                /FTId=PRO_1000018591.
SQ   SEQUENCE   219 AA;  23799 MW;  BDC6BDD7F6A60957 CRC64;
     MIKTKICGLT EVGQALATAR TGADFAGVVF AESKRRITTE KALEIAEALK PLNPRPMLVG
     VFANQTAEEV NRIASVCRLD RVQLSGNESW EYCNQVNLPV IKVIHVAEGT TAELVIQEIQ
     AGLKALKKTP VFLLDTHTKA LFGGSGQSFD WQIVKQVSLK YPVMVAGGLN PENIQGFIKI
     AKPWGIDVAS GVETDGIKDT AKIHLFIERV KDADGNRIC
//