Reviewed, UniProtKB/Swiss-Prot Q3Z6G4 (TRPF_DEHE1)

Names and origin

Protein names

Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase
      Short name=PRAI
    EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	DET1485

Organism

Dehalococcoides ethenogenes (strain 195) [Complete proteome] [HAMAP]

Taxonomic identifier

243164 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Dehalococcoidetes › Dehalococcoides

Protein attributes

Sequence length	219 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the trpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 219	219	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_1000018591

Sequences

	Sequence		Length	Mass (Da)
	Q3Z6G4-1 [UniParc]. Last modified September 27, 2005. Version 1. Checksum: BDC6BDD7F6A60957	FASTA	219	23,799
	10 20 30 40 50 60 MIKTKICGLT EVGQALATAR TGADFAGVVF AESKRRITTE KALEIAEALK PLNPRPMLVG 70 80 90 100 110 120 VFANQTAEEV NRIASVCRLD RVQLSGNESW EYCNQVNLPV IKVIHVAEGT TAELVIQEIQ 130 140 150 160 170 180 AGLKALKKTP VFLLDTHTKA LFGGSGQSFD WQIVKQVSLK YPVMVAGGLN PENIQGFIKI 190 200 210 AKPWGIDVAS GVETDGIKDT AKIHLFIERV KDADGNRIC

References

[1]

"Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides ethenogenes." Seshadri R., Adrian L., Fouts D.E., Eisen J.A., Phillippy A.M., Methe B.A., Ward N.L., Nelson W.C., DeBoy R.T., Khouri H.M., Kolonay J.F., Dodson R.J., Daugherty S.C., Brinkac L.M., Sullivan S.A., Madupu R., Nelson K.E., Kang K.H. , Impraim M., Tran K., Robinson J.M., Forberger H.A., Fraser C.M., Zinder S.H., Heidelberg J.F. Science 307:105-108(2005) [PubMed: 15637277] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000027 Genomic DNA. Translation: AAW39327.1.
RefSeq	YP_182185.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3229285.
GenomeReviews	Gene locus DET1485 in contig CP000027_GR.
KEGG	det:DET1485.
NMPDR	fig|243164.3.peg.1410.
TIGR	DET1485.
Phylogenomic databases
HOGENOM	Q3Z6G4.
OMA	Q3Z6G4. SKICGIT.
Enzyme and pathway databases
BioCyc	DETH243164:DET_1485-MON.
Family and domain databases
HAMAP	MF_00135. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPF_DEHE1

Accession

Primary (citable) accession number: Q3Z6G4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 27, 2005
Last modified:	June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)