Reviewed, UniProtKB/Swiss-Prot Q3Z422 (6PGL_SHISS)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6-P-gluconolactonase
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	SSON_0741

Organism

Shigella sonnei (strain Ss046) [Complete proteome] [HAMAP]

Taxonomic identifier

300269 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
PTM	Acetylation
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	6-phosphogluconolactonase HAMAP MF_01605		PRO_0000291472
Amino acid modifications
	Modified residue	287	1	N6-acetyllysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3Z422-1 [UniParc]. Last modified September 27, 2005. Version 1. Checksum: 25D69A26ADB6018E	FASTA	331	36,283
	10 20 30 40 50 60 MKQTVYIASP ESQQIHVWNL NHEGALTLTQ VVDVPGQVQP MVVSPDKRYL YVGVRPEFRV 70 80 90 100 110 120 LAYRIAPDDG ALTFAAESAL PGSPTHISTD HQGQFVFVGS YNAGNVSVTR LEDGLPVGVV 130 140 150 160 170 180 DVVEGLDGCH SANISPDNRT LWVPALKQDR ICLFTVSDDG HLVAQDPAEV TTVEGAGPRH 190 200 210 220 230 240 MVFHPNEQYA YCVNELNSSV DVWELKDPHG NIECVQTLDM MPENFSDTCW AADIHITPDG 250 260 270 280 290 300 RHLYACDRTA SLITVFSVSE DGSVLSKEGF QPTETQPRGF NVDHSGKYLI VAGQKSHHIS 310 320 330 VYEIVGEQGL LHEKGRYAVG QGPMWVVVNA H

References

[1]

"Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery." Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J., Xu J. , Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J., Jin Q. Nucleic Acids Res. 33:6445-6458(2005) [PubMed: 16275786] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000038 Genomic DNA. Translation: AAZ87490.1.
RefSeq	YP_309725.1.
3D structure databases
SMR	Q3Z422. Positions 1-331.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3Z422.
Genome annotation databases
GeneID	3669792.
GenomeReviews	Gene locus SSON_0741 in contig CP000038_GR.
KEGG	ssn:SSON_0741.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3Z422.
OMA	EGCHSAN.
Enzyme and pathway databases
BioCyc	SSON300269:SSO_0741-MON.
Family and domain databases
HAMAP	MF_01605. [Tree]
InterPro	IPR019405. DUF2394. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF10282. DUF2394. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

6PGL_SHISS

Accession

Primary (citable) accession number: Q3Z422

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 12, 2007
Last sequence update:	September 27, 2005
Last modified:	November 3, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)