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Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Shigella sonnei (strain Ss046)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathway: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 2912NADUniRule annotationAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSSON300269:GJJF-1603-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
Alternative name(s):
Tagaturonate dehydrogenaseUniRule annotation
Tagaturonate reductaseUniRule annotation
Gene namesi
Name:uxaBUniRule annotation
Ordered Locus Names:SSON_1607
OrganismiShigella sonnei (strain Ss046)
Taxonomic identifieri300269 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella
ProteomesiUP000002529 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 482482Altronate oxidoreductasePRO_1000044708Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ3Z1Q7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0246.
HOGENOMiHOG000029586.
KOiK00041.
OMAiHNTFCST.
OrthoDBiEOG6CVVB8.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00670. Altron_oxidoreduct.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR023668. Altronate_OxRdtase.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3Z1Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLNRRDFP GAQYPERIIQ FGEGNFLRAF VDWQIDLLNE HTDLNSGVVV
60 70 80 90 100
VRPIETSFPP SLSTQDGLYT TIIRGLNEKG EAVSDARLIR SVNREISVYS
110 120 130 140 150
EYDEFLKLAH NPEMRFVFSN TTEAGISYHA GDKFDDAPAI SYPAKLTRLL
160 170 180 190 200
FERFSHFNGA LDKGWIIIPC ELIDYNGDAL RELVLRYAQE WALPEAFIQW
210 220 230 240 250
LDQANSFCST LVDRIVTGYP RDEVAKLEEE LGYHDGFLDT AEHFYLFVIQ
260 270 280 290 300
GPKSLATELR LDKYPLNVLI VDDIKPYKER KVAILNGAHT ALVPVAFQAG
310 320 330 340 350
LDTVGEAMND AEICAFVEKA IYEEIIPVLD LPRDELESFA SAVTGRFRNP
360 370 380 390 400
YKHQLLSIAL NGMTKFRTRI LPQLLAGQKA NGTLPARLTF ALAALIAFYR
410 420 430 440 450
GERNGETYPV QDDAHWLERY QQLWSQHRDH VIGTQELVAI VLAEKDHWEQ
460 470 480
DLTQVPGLVE QVANDLDAIL EKGMREAVRP LC
Length:482
Mass (Da):54,690
Last modified:September 27, 2005 - v1
Checksum:iAC3DC98280B6862C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000038 Genomic DNA. Translation: AAZ88305.1.
RefSeqiWP_000854612.1. NC_007384.1.
YP_310540.1. NC_007384.1.

Genome annotation databases

EnsemblBacteriaiAAZ88305; AAZ88305; SSON_1607.
KEGGissn:SSON_1607.
PATRICi18737144. VBIShiSon107113_1920.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000038 Genomic DNA. Translation: AAZ88305.1.
RefSeqiWP_000854612.1. NC_007384.1.
YP_310540.1. NC_007384.1.

3D structure databases

ProteinModelPortaliQ3Z1Q7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ88305; AAZ88305; SSON_1607.
KEGGissn:SSON_1607.
PATRICi18737144. VBIShiSon107113_1920.

Phylogenomic databases

eggNOGiCOG0246.
HOGENOMiHOG000029586.
KOiK00041.
OMAiHNTFCST.
OrthoDBiEOG6CVVB8.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciSSON300269:GJJF-1603-MONOMER.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00670. Altron_oxidoreduct.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR023668. Altronate_OxRdtase.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ss046.

Entry informationi

Entry nameiUXAB_SHISS
AccessioniPrimary (citable) accession number: Q3Z1Q7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 27, 2005
Last modified: June 24, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.