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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Shigella sonnei (strain Ss046)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:SSON_2268
OrganismiShigella sonnei (strain Ss046)
Taxonomic identifieri300269 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002529 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000238161 – 548Probable malate:quinone oxidoreductaseAdd BLAST548

Structurei

3D structure databases

ProteinModelPortaliQ3YZZ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000109379
KOiK00116
OMAiEPIAATK

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

Q3YZZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKVTAMLFS MAVGLNAVSM AAKAKASEEQ ETDVLLIGGG IMSATLGTYL
60 70 80 90 100
RELEPEWSMT MVERLEGVAQ ESSNGWNNAG TGHSALMELN YTPQNADGSI
110 120 130 140 150
SIEKAVAINE AFQISRQFWA HQVERGVLRT PRSFINTVPH MSFVWGEDNV
160 170 180 190 200
NFLRARYAAL QQSSLFRGMR YSEDHAQIKE WAPLVMEGRD PQQKVAATRT
210 220 230 240 250
EIGTDVNYGE ITRQLIASLQ KKSNFSLQLS SEVRALKRND DNTWTVTVAD
260 270 280 290 300
LKNGTAQNIR AKFVFIGAGG AALKLLQESG IPEAKDYAGF PVGGQFLVSE
310 320 330 340 350
NPDVVNHHLA KVYGKASVGA PPMSVPHIDT RVLDGKRVVL FGPFATFSTK
360 370 380 390 400
FLKNGSLWDL MSSTTTSNVM PMMHVGLDNF DLVKYLVSQV MLSEEDRFEA
410 420 430 440 450
LKEYYPQAKK EDWRLWQAGQ RVQIIKRDAD KGGVLRLGTE VVSDQQGTIA
460 470 480 490 500
ALLGASPGAS TAAPIMLDLL EKVFGDRVSS PQWQATLKAI VPSYGRKLNG
510 520 530 540
DVAATERELQ YTSEVLGLKY DKPQAADSTP KPQLKPQPVQ KEVADIAL
Length:548
Mass (Da):60,231
Last modified:September 27, 2005 - v1
Checksum:i2E18ABBC45E6D238
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000038 Genomic DNA Translation: AAZ88915.1

Genome annotation databases

EnsemblBacteriaiAAZ88915; AAZ88915; SSON_2268
KEGGissn:SSON_2268

Similar proteinsi

Entry informationi

Entry nameiMQO_SHISS
AccessioniPrimary (citable) accession number: Q3YZZ7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 27, 2005
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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