ID   TTDA_SHISS              Reviewed;         303 AA.
AC   Q3YXI2;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   03-NOV-2009, entry version 30.
DE   RecName: Full=L(+)-tartrate dehydratase subunit alpha;
DE            Short=L-TTD alpha;
DE            EC=4.2.1.32;
GN   Name=ttdA; OrderedLocusNames=SSON_3198;
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- CATALYTIC ACTIVITY: (R,R)-tartrate = oxaloacetate + H(2)O.
CC   -!- COFACTOR: Iron-sulfur (By similarity).
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the class-I fumarase family.
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DR   EMBL; CP000038; AAZ89780.1; -; Genomic_DNA.
DR   RefSeq; YP_312015.1; -.
DR   STRING; Q3YXI2; -.
DR   GeneID; 3669354; -.
DR   GenomeReviews; CP000038_GR; SSON_3198.
DR   KEGG; ssn:SSON_3198; -.
DR   HOGENOM; Q3YXI2; -.
DR   OMA; VNACPPL; -.
DR   BioCyc; SSON300269:SSO_3198-MON; -.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008730; F:L(+)-tartrate dehydratase activity; IEA:EC.
DR   InterPro; IPR004646; TtdA_fumA_fumB.
DR   Pfam; PF05681; Fumerase; 1.
DR   TIGRFAMs; TIGR00722; ttdA_fumA_fumB; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Complete proteome; Iron; Iron-sulfur; Lyase; Metal-binding.
FT   CHAIN         1    303       L(+)-tartrate dehydratase subunit alpha.
FT                                /FTId=PRO_0000262702.
FT   METAL        71     71       Iron-sulfur (By similarity).
FT   METAL       190    190       Iron-sulfur (By similarity).
FT   METAL       277    277       Iron-sulfur (By similarity).
SQ   SEQUENCE   303 AA;  32734 MW;  CBE29FEB6C47DB81 CRC64;
     MMSESNKQQA VNKLTEIVAN FTAMISTRMP DDVVDKLKQL KDAETSSMGK IIYHTMFDNM
     QKAIDLNRPA CQDTGEIMFF VKVGSRFPLL GELQSILKQA VEEATVKAPL RHNAVEIFDE
     VNTGKNTGSG VPWVTWDIIP DNDDAEIEVY MAGGGCTLPG RSKVLMPSEG YEGVVKFVFE
     NISTLAVNAC PPVLVGVGIA TSVETAAVLS RKAILRPIGS RHPNPKAAEL ELRLEEGLNR
     LGIGPQGLTG NSSVMGVHIE SAARHPSTIG VAVSTGCWAH RRGTLLVHAD LTFENLSHTR
     SAL
//