Reviewed, UniProtKB/Swiss-Prot Q3YX25 (NANE_SHISS)

Names and origin

Protein names

Recommended name:
    Putative N-acetylmannosamine-6-phosphate 2-epimerase
    EC=5.1.3.9
Alternative name(s):
    ManNAc-6-P epimerase

Gene names

Name:	nanE
Ordered Locus Names:	SSON_3364

Organism

Shigella sonnei (strain Ss046) [Complete proteome] [HAMAP]

Taxonomic identifier

300269 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	229 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) Potential.
Catalytic activity	N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate. HAMAP MF_01235
Pathway	Amino-sugar metabolism; N-acetylneuraminic acid degradation; D-fructose 6-phosphate from N-acetylneuraminic acid: step 3/5. HAMAP MF_01235
Sequence similarities	Belongs to the nanE family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	N-acetylmannosamine metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	N-acylglucosamine-6-phosphate 2-epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 229	229	Putative N-acetylmannosamine-6-phosphate 2-epimerase HAMAP MF_01235		PRO_0000301483

Sequences

	Sequence		Length	Mass (Da)
	Q3YX25-1 [UniParc]. Last modified September 27, 2005. Version 1. Checksum: 59ABD7A0A98FC983	FASTA	229	24,102
	10 20 30 40 50 60 MSLLAQLDQK IAANGGLIVS CQPIPDSPLD KPEIVAAMAL AAEQAGAVAI RIEGVANLQA 70 80 90 100 110 120 TRAVVSVPII GIVKRDLEDS PVRITAYIED VDALAQAGAD IIAIDGTDRP RPVPVETLLA 130 140 150 160 170 180 RIHHHGLLAM TDCSTPEDGL ACQKLGAEII GTTLSGYTTP ETPEEPDLAL VKTLSEAGCR 190 200 210 220 VIAEGRYNTP AQAADAMRHG AWAVTVGSAI TRLEHICQWY NTAMKKAVL

References

[1]

"Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery." Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J., Xu J. , Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J., Jin Q. Nucleic Acids Res. 33:6445-6458(2005) [PubMed: 16275786] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000038 Genomic DNA. Translation: AAZ89937.1.
RefSeq	YP_312172.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3667033.
GenomeReviews	Gene locus SSON_3364 in contig CP000038_GR.
KEGG	ssn:SSON_3364.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3YX25.
OMA	Q3YX25. YNTPELA.
Enzyme and pathway databases
BioCyc	SSON300269:SSO_3364-MON.
Family and domain databases
HAMAP	MF_01235. [Tree]
InterPro	IPR007260. NanE. [Graphical view]
Pfam	PF04131. NanE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NANE_SHISS

Accession

Primary (citable) accession number: Q3YX25

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 27, 2005
Last modified:	June 16, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)