UniProtKB - Q3YW11 (KGUA_SHISS)
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Protein
Guanylate kinase
Gene
gmk
Organism
Shigella sonnei (strain Ss046)
Status
Functioni
Essential for recycling GMP and indirectly, cGMP.UniRule annotation
Catalytic activityi
ATP + GMP = ADP + GDP.UniRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 11 – 18 | ATPUniRule annotation | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- guanylate kinase activity Source: UniProtKB-EC
Keywordsi
Molecular function | Kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)Alternative name(s): GMP kinaseUniRule annotation |
Gene namesi | Name:gmkUniRule annotation Ordered Locus Names:SSON_3757 |
Organismi | Shigella sonnei (strain Ss046) |
Taxonomic identifieri | 300269 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Shigella › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000266402 | 1 – 207 | Guanylate kinaseAdd BLAST | 207 |
Structurei
3D structure databases
ProteinModelPortali | Q3YW11 |
SMRi | Q3YW11 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 184 | Guanylate kinase-likeUniRule annotationAdd BLAST | 181 |
Sequence similaritiesi
Belongs to the guanylate kinase family.UniRule annotation
Phylogenomic databases
HOGENOMi | HOG000037638 |
KOi | K00942 |
OMAi | AGNYYGT |
Family and domain databases
HAMAPi | MF_00328 Guanylate_kinase, 1 hit |
InterProi | View protein in InterPro IPR008145 GK/Ca_channel_bsu IPR008144 Guanylate_kin-like_dom IPR017665 Guanylate_kinase IPR020590 Guanylate_kinase_CS IPR027417 P-loop_NTPase |
Pfami | View protein in Pfam PF00625 Guanylate_kin, 1 hit |
SMARTi | View protein in SMART SM00072 GuKc, 1 hit |
SUPFAMi | SSF52540 SSF52540, 1 hit |
TIGRFAMsi | TIGR03263 guanyl_kin, 1 hit |
PROSITEi | View protein in PROSITE PS00856 GUANYLATE_KINASE_1, 1 hit PS50052 GUANYLATE_KINASE_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q3YW11-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQGTLYIVS APSGAGKSSL IQALLKTQPL YDTQVSVSHT TRQPRPGEVH
60 70 80 90 100
GEHYFFVNHD EFKEMISRDA FLEHAEVFGN YYGTSREAIE QVLATGVDVF
110 120 130 140 150
LDIDWQGAQQ IRQKMPHARS IFILPPSKIE LDRRLRGRGQ DSEEVIAKRM
160 170 180 190 200
AQAVAEMSHY AEYDYLIVND DFDTALTDLK TIIRAERLRM SRQKQRHDAL
ISKLLAD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000038 Genomic DNA Translation: AAZ90301.1 |
Genome annotation databases
EnsemblBacteriai | AAZ90301; AAZ90301; SSON_3757 |
KEGGi | ssn:SSON_3757 |
Similar proteinsi
Entry informationi
Entry namei | KGUA_SHISS | |
Accessioni | Q3YW11Primary (citable) accession number: Q3YW11 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 12, 2006 |
Last sequence update: | September 27, 2005 | |
Last modified: | March 28, 2018 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |