ID   RHAA_SHISS              Reviewed;         419 AA.
AC   Q3YV73;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=L-rhamnose isomerase;
DE            EC=5.3.1.14;
GN   Name=rhaA; OrderedLocusNames=SSON_4073;
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- CATALYTIC ACTIVITY: L-rhamnose = L-rhamnulose.
CC   -!- COFACTOR: Binds 1 manganese ion per subunit (By similarity).
CC   -!- PATHWAY: Carbohydrate degradation; L-rhamnose degradation;
CC       glycerone phosphate from L-rhamnose: step 1/3.
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the rhamnose isomerase family.
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DR   EMBL; CP000038; AAZ90589.1; -; Genomic_DNA.
DR   RefSeq; YP_312824.1; -.
DR   SMR; Q3YV73; 1-418.
DR   GeneID; 3669300; -.
DR   GenomeReviews; CP000038_GR; SSON_4073.
DR   KEGG; ssn:SSON_4073; -.
DR   HOGENOM; Q3YV73; -.
DR   OMA; Q3YV73; GSHEFYM.
DR   BioCyc; SSON300269:SSO_4073-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008740; F:L-rhamnose isomerase activity; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019299; P:rhamnose metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00541; -; 1.
DR   InterPro; IPR009308; Rhamnose_isomerase.
DR   InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR   Gene3D; G3DSA:3.20.20.150; Xyl_isomerase-like_TIM-brl; 1.
DR   Pfam; PF06134; RhaA; 1.
DR   TIGRFAMs; TIGR01748; rhaA; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Isomerase; Manganese; Metal-binding;
KW   Rhamnose metabolism.
FT   CHAIN         1    419       L-rhamnose isomerase.
FT                                /FTId=PRO_1000017723.
FT   METAL       262    262       Manganese (By similarity).
FT   METAL       294    294       Manganese (By similarity).
FT   METAL       296    296       Manganese (By similarity).
SQ   SEQUENCE   419 AA;  47152 MW;  865C5F2E90643052 CRC64;
     MTTQLEQAWE LAKQRFAAVG IDVEEALRQL DRLPVSMHCW QGDDVSGFEN PEGSLTGGIQ
     AIGNYPGKAR NASELRADLE QAMRLIPGPK RLNLHAIYLE SDTPVSRDQI KPEHFKNWVE
     WAKANQLGLD FNPSCFSHPL SADGFTLSHP DDSIRQFWID HCKASRRVSA YFGEQLGTPS
     VMNIWIPDGM KDITVDRLAP RQRLLAALDE VISEKLDPAH HIDAVESKLF GIGAESYTVG
     SNEFYMGYAT SRQTALCLDA GHFHPTEVIS DKISAAMLYV PQLLLHVSRP VRWDSDHVVL
     LDDETQAIAS EIVRHDLFDR VHIGLDFFDA SINRIAAWVI GTRNMKKALL RALLEPTAEL
     RKLEAAGDYT ARLALLEEQK SLPWQAVWEM YCQRHDTPAG SEWLESVRAY EKAILSQRG
//