ID   CDH_SHISS               Reviewed;         251 AA.
AC   Q3YV60;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=CDP-diacylglycerol pyrophosphatase;
DE            EC=3.6.1.26;
DE   AltName: Full=CDP-diacylglycerol phosphatidylhydrolase;
DE   AltName: Full=CDP-diglyceride hydrolase;
GN   Name=cdh; OrderedLocusNames=SSON_4087;
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- CATALYTIC ACTIVITY: CDP-diacylglycerol + H(2)O = CMP +
CC       phosphatidate.
CC   -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol degradation;
CC       phosphatidate from CDP-diacylglycerol: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane
CC       protein (By similarity).
CC   -!- SIMILARITY: Belongs to the cdh family.
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DR   EMBL; CP000038; AAZ90602.1; -; Genomic_DNA.
DR   RefSeq; YP_312837.1; -.
DR   GeneID; 3669314; -.
DR   GenomeReviews; CP000038_GR; SSON_4087.
DR   KEGG; ssn:SSON_4087; -.
DR   HOGENOM; Q3YV60; -.
DR   OMA; Q3YV60; EIQDHEC.
DR   BioCyc; SSON300269:SSO_4087-MON; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008715; F:CDP-diacylglycerol diphosphatase activity; IEA:HAMAP.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00319; -; 1.
DR   InterPro; IPR003763; CDP-diacylglyc_Pase_bac.
DR   InterPro; IPR015993; CDP-diacylglyc_Pase_proteobac.
DR   Pfam; PF02611; CDH; 1.
DR   PIRSF; PIRSF001273; CDH; 1.
DR   TIGRFAMs; TIGR00672; cdh; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Complete proteome; Hydrolase;
KW   Membrane; Phospholipid biosynthesis; Transmembrane.
FT   CHAIN         1    251       CDP-diacylglycerol pyrophosphatase.
FT                                /FTId=PRO_1000019269.
FT   TRANSMEM      4     24       Potential.
SQ   SEQUENCE   251 AA;  28383 MW;  C987D3A4B12BE5F3 CRC64;
     MKKAGLLFLV MIVIAVVAAG IGYWKLTGEE SDTLRKIVLE ECLPNQQQNQ NPSPCAEVKP
     NAGYVVLKDL NGPLQYLLMP TYRINGTESP LLTDPSTPNF FWLAWQARDF MSKKYGQPVP
     DRAVSLAINS RTGRTQNHFH IHISCIRPDV REQLDNNLAN ISSRWLPLPG GLRGHEYLAR
     RVTESELVQR SPFMMLAEEV PEAREHMGSY GLAMVRQSDN SFVLLATQRN LLTLNRASAE
     EIQDHQCEIL R
//