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Protein

CDP-diacylglycerol pyrophosphatase

Gene

cdh

Organism
Shigella sonnei (strain Ss046)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

CDP-diacylglycerol + H2O = CMP + phosphatidate.UniRule annotation

Pathwayi: CDP-diacylglycerol degradation

This protein is involved in step 1 of the subpathway that synthesizes phosphatidate from CDP-diacylglycerol.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. CDP-diacylglycerol pyrophosphatase (cdh)
This subpathway is part of the pathway CDP-diacylglycerol degradation, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes phosphatidate from CDP-diacylglycerol, the pathway CDP-diacylglycerol degradation and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00609; UER00664

Names & Taxonomyi

Protein namesi
Recommended name:
CDP-diacylglycerol pyrophosphataseUniRule annotation (EC:3.6.1.26UniRule annotation)
Alternative name(s):
CDP-diacylglycerol phosphatidylhydrolaseUniRule annotation
CDP-diglyceride hydrolaseUniRule annotation
Gene namesi
Name:cdhUniRule annotation
Ordered Locus Names:SSON_4087
OrganismiShigella sonnei (strain Ss046)
Taxonomic identifieri300269 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002529 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000192691 – 251CDP-diacylglycerol pyrophosphataseAdd BLAST251

Structurei

3D structure databases

ProteinModelPortaliQ3YV60
SMRiQ3YV60
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cdh family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000048713
KOiK01521
OMAiSPFIMLA

Family and domain databases

Gene3Di3.30.428.30, 1 hit
HAMAPiMF_00319 Cdh, 1 hit
InterProiView protein in InterPro
IPR003763 CDP-diacylglyc_Pase
IPR015993 CDP-diacylglyc_Pase_proteobac
IPR038433 CDP-diacylglyc_Pase_sf
IPR036265 HIT-like_sf
PfamiView protein in Pfam
PF02611 CDH, 1 hit
PIRSFiPIRSF001273 CDH, 1 hit
SUPFAMiSSF54197 SSF54197, 1 hit
TIGRFAMsiTIGR00672 cdh, 1 hit

Sequencei

Sequence statusi: Complete.

Q3YV60-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKAGLLFLV MIVIAVVAAG IGYWKLTGEE SDTLRKIVLE ECLPNQQQNQ
60 70 80 90 100
NPSPCAEVKP NAGYVVLKDL NGPLQYLLMP TYRINGTESP LLTDPSTPNF
110 120 130 140 150
FWLAWQARDF MSKKYGQPVP DRAVSLAINS RTGRTQNHFH IHISCIRPDV
160 170 180 190 200
REQLDNNLAN ISSRWLPLPG GLRGHEYLAR RVTESELVQR SPFMMLAEEV
210 220 230 240 250
PEAREHMGSY GLAMVRQSDN SFVLLATQRN LLTLNRASAE EIQDHQCEIL

R
Length:251
Mass (Da):28,383
Last modified:September 27, 2005 - v1
Checksum:iC987D3A4B12BE5F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000038 Genomic DNA Translation: AAZ90602.1

Genome annotation databases

EnsemblBacteriaiAAZ90602; AAZ90602; SSON_4087
KEGGissn:SSON_4087

Similar proteinsi

Entry informationi

Entry nameiCDH_SHISS
AccessioniPrimary (citable) accession number: Q3YV60
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 27, 2005
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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