ID   NUDC_SHISS              Reviewed;         257 AA.
AC   Q3YUY8;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 28.
DE   RecName: Full=NADH pyrophosphatase;
DE            EC=3.6.1.22;
GN   Name=nudC; OrderedLocusNames=SSON_4169;
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- CATALYTIC ACTIVITY: NAD(+) + H(2)O = AMP + NMN.
CC   -!- COFACTOR: Divalent ions. Manganese or magnesium (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. NudC subfamily.
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DR   EMBL; CP000038; AAZ90674.1; -; Genomic_DNA.
DR   RefSeq; YP_312909.1; -.
DR   SMR; Q3YUY8; 1-257.
DR   GeneID; 3669085; -.
DR   GenomeReviews; CP000038_GR; SSON_4169.
DR   KEGG; ssn:SSON_4169; -.
DR   HOGENOM; Q3YUY8; -.
DR   OMA; Q3YUY8; SPCIIVA.
DR   BioCyc; SSON300269:SSO_4169-MON; -.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:HAMAP.
DR   GO; GO:0000210; F:NAD+ diphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_00297; -; 1.
DR   InterPro; IPR015375; NADH_PPase-like_N.
DR   InterPro; IPR000086; NUDIX_hydrolase_core.
DR   InterPro; IPR015376; Znr_NADH_PPase.
DR   Gene3D; G3DSA:3.90.79.10; NUDIX_hydrolase; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   Pfam; PF09296; NUDIX-like; 1.
DR   Pfam; PF09297; zf-NADH-PPase; 1.
DR   PROSITE; PS00893; NUDIX; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Magnesium; Manganese; NAD.
FT   CHAIN         1    257       NADH pyrophosphatase.
FT                                /FTId=PRO_0000232124.
FT   MOTIF       159    180       Nudix box.
SQ   SEQUENCE   257 AA;  29689 MW;  368FAE0480AF4CB3 CRC64;
     MDRIIEKLDH GWWVVSHEQK LWLPKGELPY GEAANFDLVG QRALQIGEWQ GEPVWLVQQQ
     RRHDMGSVRQ VIDLDVGLFQ LAGRGVQLAE FYRSHKYCGY CGHEMYPSKT EWAMLCSHCR
     ERYYPQIAPC IIVAIRRDDS ILLAQHTRHR NGVHTVLAGF VEVGETLEQA VAREVMEESG
     IKVKNLRYVT SQPWPFPQSL MTAFMAEYDS GDIVIDPKEL LEANWYRYDD LPLLPPPGTV
     ARRLIEDTVA MCRAEYE
//