Reviewed, UniProtKB/Swiss-Prot Q3YUF1 (ULAE_SHISS)

Names and origin

Protein names

Recommended name:
    L-ribulose-5-phosphate 3-epimerase ulaE
    EC=5.1.3.22
Alternative name(s):
    L-xylulose-5-phosphate 3-epimerase
    L-ascorbate utilization protein E

Gene names

Name:	ulaE
Ordered Locus Names:	SSON_4379

Organism

Shigella sonnei (strain Ss046) [Complete proteome] [HAMAP]

Taxonomic identifier

300269 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization By similarity.
Catalytic activity	L-ribulose 5-phosphate = L-xylulose 5-phosphate. HAMAP MF_01951
Pathway	Cofactor degradation; L-ascorbic acid degradation; D-xylulose 5-phosphate from L-ascorbic acid: step 3/4. HAMAP MF_01951
Induction	Induced by L-ascorbate. Repressed by ulaR By similarity.
Sequence similarities	Belongs to the HUMPI family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-ascorbic acid metabolic process Inferred from electronic annotation. Source: HAMAP carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	L-ribulose-5-phosphate 3-epimerase activity Inferred from electronic annotation. Source: HAMAP intramolecular oxidoreductase activity, interconverting aldoses and ketoses Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 284	284	L-ribulose-5-phosphate 3-epimerase ulaE HAMAP MF_01951		PRO_0000233260

Sequences

	Sequence		Length	Mass (Da)
	Q3YUF1-1 [UniParc]. Last modified September 27, 2005. Version 1. Checksum: 16D6E726374732ED	FASTA	284	32,075
	10 20 30 40 50 60 MLSKQIPLGI YEKALPAGEC WLERLRLAKT LGFDFVEMSV DETDERLSRL DWSREQRLAL 70 80 90 100 110 120 VNAIVETGVR VPSMCLSAHR RFPLGSEDDA VRAQGLEIMR KAIQFAQDVG IRVIQLAGYD 130 140 150 160 170 180 VYYQEANNET RRRFRDGLKE SVEMASRAQV TLAMEIMDYP LMNSISKALG YAHYLNNPWF 190 200 210 220 230 240 QLYPDIGNLS AWDNDVQMEL QAGIGHIVAV HVKDTKPGVF KNVPFGEGVV DFERCFETLK 250 260 270 280 QSGYCGPYLI EMWSETAEDP AAEVVKARDW VKARMAKAGT VEAA

References

[1]

"Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery." Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J., Xu J. , Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J., Jin Q. Nucleic Acids Res. 33:6445-6458(2005) [PubMed: 16275786] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000038 Genomic DNA. Translation: AAZ90861.1.
RefSeq	YP_313096.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3668421.
GenomeReviews	Gene locus SSON_4379 in contig CP000038_GR.
KEGG	ssn:SSON_4379.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3YUF1.
OMA	Q3YUF1. VVKARDW.
Enzyme and pathway databases
BioCyc	SSON300269:SSO_4379-MON.
Family and domain databases
HAMAP	MF_01951. [Tree]
InterPro	IPR004560. Hxl6Piso_put. IPR013022. Xyl_isomerase-like_TIM-brl. IPR012307. Xyl_isomerase-typ_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF01261. AP_endonuc_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00542. hxl6Piso_put. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ULAE_SHISS

Accession

Primary (citable) accession number: Q3YUF1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2006
Last sequence update:	September 27, 2005
Last modified:	June 16, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)