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Protein

Probable protein kinase UbiB

Gene

Ecaj_0250

Organism
Ehrlichia canis (strain Jake)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. oxidoreductase activity Source: UniProtKB-KW
  3. protein kinase activity Source: InterPro

GO - Biological processi

  1. ubiquinone biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, OxidoreductaseImported, Transferase

Keywords - Biological processi

Ubiquinone biosynthesisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciECAN269484:GI02-268-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein kinase UbiBSAAS annotation (EC:2.7.-.-SAAS annotation)
Gene namesi
Ordered Locus Names:Ecaj_0250Imported
OrganismiEhrlichia canis (strain Jake)Imported
Taxonomic identifieri269484 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
ProteomesiUP000000435: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membraneSAAS annotation, Cell membrane, Membrane

Interactioni

Protein-protein interaction databases

STRINGi269484.Ecaj_0250.

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiCOG0661.
HOGENOMiHOG000264438.
KOiK03688.
OMAiWVLVREG.
OrthoDBiEOG61P6SS.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR010232. UbiB.
IPR004147. UbiB_dom.
[Graphical view]
PfamiPF03109. ABC1. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
TIGRFAMsiTIGR01982. UbiB. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3YSK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSIFSSIIS LLNILSILVR YNVLPYTYFF ADRSIRRKSQ GERVTMALQR
60 70 80 90 100
LGPIFIKFGQ SMSSRADIIG EEIANHLLCL CDKLPAFPYA DVVRIIEEDF
110 120 130 140 150
KCNISEMFCE FEQKPIAAAS IAQVHKAKDI DGNVRAVKVL RPKIEKIFER
160 170 180 190 200
DIKLMFWLAR LAQYFSRFRR FQLLQLVQTF REICRMEIDL RFEAANAEEL
210 220 230 240 250
RSNIQDDDGC YVPEVDWTKT TRRVLTLEWV DAVPIYSVYK SENCETLVRN
260 270 280 290 300
LIFCFCNQVY RDRFFHADMH PGNLMVDTKG RIVIIDFGIV GRLDKATCMY
310 320 330 340 350
VTEILVGFLK KDYQYVADIH YRAGYVDAKY SSFITACRAI GEPIVGKNAE
360 370 380 390 400
NISISMLLTQ LFKITSDFDM KLQPQLFLLQ KTTVLVEGVC RQLCPEINMW
410 420 430 440 450
KVAELWMEKY SIEKNKYIQK LKRSYICQTI NDIPSFMKKV DKSLDVISNY
460 470 480
QELNKANIGI NRDIIWALIV GGLIIKLIIG
Length:480
Mass (Da):55,681
Last modified:September 27, 2005 - v1
Checksum:i2442289207E6107D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000107 Genomic DNA. Translation: AAZ68297.1.
RefSeqiWP_011304375.1. NC_007354.1.
YP_302895.1. NC_007354.1.

Genome annotation databases

EnsemblBacteriaiAAZ68297; AAZ68297; Ecaj_0250.
GeneIDi3618340.
KEGGiecn:Ecaj_0250.
PATRICi20574008. VBIEhrCan118076_0268.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000107 Genomic DNA. Translation: AAZ68297.1.
RefSeqiWP_011304375.1. NC_007354.1.
YP_302895.1. NC_007354.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269484.Ecaj_0250.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ68297; AAZ68297; Ecaj_0250.
GeneIDi3618340.
KEGGiecn:Ecaj_0250.
PATRICi20574008. VBIEhrCan118076_0268.

Phylogenomic databases

eggNOGiCOG0661.
HOGENOMiHOG000264438.
KOiK03688.
OMAiWVLVREG.
OrthoDBiEOG61P6SS.

Enzyme and pathway databases

UniPathwayiUPA00232.
BioCyciECAN269484:GI02-268-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR010232. UbiB.
IPR004147. UbiB_dom.
[Graphical view]
PfamiPF03109. ABC1. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
TIGRFAMsiTIGR01982. UbiB. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of the obligately intracellular bacterium Ehrlichia canis reveals themes of complex membrane structure and immune evasion strategies."
    Mavromatis K., Doyle C.K., Lykidis A., Ivanova N., Francino M.P., Chain P., Shin M., Malfatti S., Larimer F., Copeland A., Detter J.C., Land M., Richardson P.M., Yu X.J., Walker D.H., McBride J.W., Kyrpides N.C.
    J. Bacteriol. 188:4015-4023(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JakeImported.

Entry informationi

Entry nameiQ3YSK8_EHRCJ
AccessioniPrimary (citable) accession number: Q3YSK8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: March 4, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.