ID   DCD_EHRCJ               Reviewed;         187 AA.
AC   Q3YRB6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Deoxycytidine triphosphate deaminase;
DE            Short=dCTP deaminase;
DE            EC=3.5.4.13;
GN   Name=dcd; OrderedLocusNames=Ecaj_0707;
OS   Ehrlichia canis (strain Jake).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Ehrlichia.
OX   NCBI_TaxID=269484;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16707693; DOI=10.1128/JB.01837-05;
RA   Mavromatis K., Doyle C.K., Lykidis A., Ivanova N., Francino M.P.,
RA   Chain P., Shin M., Malfatti S., Larimer F., Copeland A., Detter J.C.,
RA   Land M., Richardson P.M., Yu X.J., Walker D.H., McBride J.W.,
RA   Kyrpides N.C.;
RT   "The genome of the obligately intracellular bacterium Ehrlichia canis
RT   reveals themes of complex membrane structure and immune evasion
RT   strategies.";
RL   J. Bacteriol. 188:4015-4023(2006).
CC   -!- CATALYTIC ACTIVITY: dCTP + H(2)O = dUTP + NH(3).
CC   -!- PATHWAY: Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP
CC       (dUTP route): step 1/2.
CC   -!- SIMILARITY: Belongs to the dCTP deaminase family.
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DR   EMBL; CP000107; AAZ68739.1; -; Genomic_DNA.
DR   RefSeq; YP_303337.1; -.
DR   GeneID; 3617907; -.
DR   GenomeReviews; CP000107_GR; Ecaj_0707.
DR   KEGG; ecn:Ecaj_0707; -.
DR   HOGENOM; Q3YRB6; -.
DR   OMA; Q3YRB6; CAQVLFF.
DR   BioCyc; ECAN269484:ECAJ_0707-MON; -.
DR   GO; GO:0008829; F:dCTP deaminase activity; IEA:HAMAP.
DR   GO; GO:0006229; P:dUTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0009220; P:pyrimidine ribonucleotide biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00146; -; 1.
DR   InterPro; IPR011962; dCTP_deam.
DR   ProDom; PD004900; dCTP_deaminase; 1.
DR   TIGRFAMs; TIGR02274; dCTP_deam; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Nucleotide metabolism.
FT   CHAIN         1    187       Deoxycytidine triphosphate deaminase.
FT                                /FTId=PRO_1000009719.
SQ   SEQUENCE   187 AA;  21098 MW;  E719F09D0A5071C0 CRC64;
     MSVMPDHWIK DKAIQEKMID PFIDYKESSG ILSYGLSSYG YDARIDNKFK IFTNINPVTV
     DPKNFPLGSF IDKEEDICII PPNSFVLAKT VEYFKIPKDI LVMCVGKSTY ARCGIVVNVT
     PLEPGWEGYV TLEFSNTTPL PAKIYAFEGA CQFIFLKGDS QCSLSYNEMK GKYMKQLDVT
     LPIVNNS
//