Reviewed, UniProtKB/Swiss-Prot Q3YRB6 (DCD_EHRCJ)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Ecaj_0707

Organism

Ehrlichia canis (strain Jake) [Complete proteome] [HAMAP]

Taxonomic identifier

269484 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009719

Sequences

	Sequence		Length	Mass (Da)
	Q3YRB6-1 [UniParc]. Last modified September 27, 2005. Version 1. Checksum: E719F09D0A5071C0	FASTA	187	21,098
	10 20 30 40 50 60 MSVMPDHWIK DKAIQEKMID PFIDYKESSG ILSYGLSSYG YDARIDNKFK IFTNINPVTV 70 80 90 100 110 120 DPKNFPLGSF IDKEEDICII PPNSFVLAKT VEYFKIPKDI LVMCVGKSTY ARCGIVVNVT 130 140 150 160 170 180 PLEPGWEGYV TLEFSNTTPL PAKIYAFEGA CQFIFLKGDS QCSLSYNEMK GKYMKQLDVT LPIVNNS

References

[1]

"The genome of the obligately intracellular bacterium Ehrlichia canis reveals themes of complex membrane structure and immune evasion strategies." Mavromatis K., Doyle C.K., Lykidis A., Ivanova N., Francino M.P., Chain P., Shin M., Malfatti S., Larimer F., Copeland A., Detter J.C., Land M., Richardson P.M., Yu X.J., Walker D.H., McBride J.W., Kyrpides N.C. J. Bacteriol. 188:4015-4023(2006) [PubMed: 16707693] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000107 Genomic DNA. Translation: AAZ68739.1.
RefSeq	YP_303337.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3617907.
GenomeReviews	Gene locus Ecaj_0707 in contig CP000107_GR.
KEGG	ecn:Ecaj_0707.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3YRB6.
OMA	Q3YRB6. CAQVLFF.
Enzyme and pathway databases
BioCyc	ECAN269484:ECAJ_0707-MON.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_EHRCJ

Accession

Primary (citable) accession number: Q3YRB6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 27, 2005
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)