Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Isocitrate dehydrogenase (NAD+)

Gene

Ecaj_0890

Organism
Ehrlichia canis (strain Jake)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciECAN269484:GI02-928-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase (NAD+)Imported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Ecaj_0890Imported
OrganismiEhrlichia canis (strain Jake)Imported
Taxonomic identifieri269484 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
ProteomesiUP000000435 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi269484.Ecaj_0890.

Structurei

3D structure databases

ProteinModelPortaliQ3YQT4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0473.
HOGENOMiHOG000021113.
KOiK00031.
OMAiLRPCKTY.
OrthoDBiEOG65XN31.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3YQT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIPITVAYG DGIGPEIMEA VLLILSEAES GLVIETIEVG HNLYKKEWSS
60 70 80 90 100
GIAPSSWDSI FRTKVLLKSP TMTPQGQGHK SLNVTLRKKL GLYANIRPCI
110 120 130 140 150
SYHPVIKTKY PNLNIVIIRE NEEDTYTGIE HRLTSDTYQC SKVITRSGSE
160 170 180 190 200
RICNYAFHYA TVHNRKKVTC LIKDNIMKMT DGIFHKSFSK IAENYPSITS
210 220 230 240 250
DHYIVDIGMA KVAANPENFD VIVTTNLYGD IVSDIVAELS GSIGLAGSAN
260 270 280 290 300
IGDNYAMFEA VHGSAPDIAG KNIANPSGLL NAAIQMLIYL KKFDKAELIY
310 320 330 340 350
NALLKTLEDG MHTADIYQSQ VSKGKVSTMG FAKAIIDNFG QSPTQFPKSI
360 370 380 390 400
FQNSAGESGI SYTYKPSYAT KVLVGVDLSI SCDSADLNLK QLISNIQGVT
410 420 430 440 450
HDKLELVLIH SKGLEIWPDE SSNANLSYMD QICCRFYMKG QSDKIVNEHV
460 470 480
NQLLFDMSKK KIDVVKMEKL YLYDNQPGFF TM
Length:482
Mass (Da):53,398
Last modified:September 27, 2005 - v1
Checksum:i2F767FE4387A9A5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000107 Genomic DNA. Translation: AAZ68921.1.
RefSeqiWP_011304997.1. NC_007354.1.
YP_303519.1. NC_007354.1.

Genome annotation databases

EnsemblBacteriaiAAZ68921; AAZ68921; Ecaj_0890.
KEGGiecn:Ecaj_0890.
PATRICi20575458. VBIEhrCan118076_0973.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000107 Genomic DNA. Translation: AAZ68921.1.
RefSeqiWP_011304997.1. NC_007354.1.
YP_303519.1. NC_007354.1.

3D structure databases

ProteinModelPortaliQ3YQT4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269484.Ecaj_0890.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ68921; AAZ68921; Ecaj_0890.
KEGGiecn:Ecaj_0890.
PATRICi20575458. VBIEhrCan118076_0973.

Phylogenomic databases

eggNOGiCOG0473.
HOGENOMiHOG000021113.
KOiK00031.
OMAiLRPCKTY.
OrthoDBiEOG65XN31.

Enzyme and pathway databases

BioCyciECAN269484:GI02-928-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR014273. Isocitrate_DH_aproteobac-typ.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02924. ICDH_alpha. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of the obligately intracellular bacterium Ehrlichia canis reveals themes of complex membrane structure and immune evasion strategies."
    Mavromatis K., Doyle C.K., Lykidis A., Ivanova N., Francino M.P., Chain P., Shin M., Malfatti S., Larimer F., Copeland A., Detter J.C., Land M., Richardson P.M., Yu X.J., Walker D.H., McBride J.W., Kyrpides N.C.
    J. Bacteriol. 188:4015-4023(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JakeImported.

Entry informationi

Entry nameiQ3YQT4_EHRCJ
AccessioniPrimary (citable) accession number: Q3YQT4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: May 27, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.