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Protein
Submitted name:

SIGLEC-H

Gene

Siglech

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • cargo receptor activity Source: MGI

GO - Biological processi

  • receptor-mediated endocytosis Source: MGI

Names & Taxonomyi

Protein namesi
Submitted name:
SIGLEC-HImported
Gene namesi
Name:SiglechImported
Synonyms:Siglec-HImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2443256. Siglech.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei266 – 286HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • cell surface Source: MGI
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500423061519 – 309Sequence analysisAdd BLAST291

Proteomic databases

PaxDbiQ3Y597.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 141Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST110
Domaini151 – 234Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST84

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IJT6. Eukaryota.
ENOG410YKZU. LUCA.
HOVERGENiHBG036161.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
PfamiView protein in Pfam
PF07686. V-set. 1 hit.
SMARTiView protein in SMART
SM00409. IG. 2 hits.
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 2 hits.

Sequencei

Sequence statusi: Complete.

Q3Y597-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLSLLLPLL WVLKWASGNC FILPREVIGT YPSLTLELQS VTVQEGLCVL
60 70 80 90 100
VPCHLIEYPM NRWSDAAFGY WFHEGENTHP DSLVATNKPY QLVQKEMQSR
110 120 130 140 150
FHFSGDCSLD IRDAQKGDNG SYFFRLEKGG KTWNFCEERI SVHVTDLTHS
160 170 180 190 200
PNISIPQTLE LGRPTNVMCS VPWACERGTP PIFSWMSAAL ISLGPTTTLS
210 220 230 240 250
SVLTLTPRLQ DHGTNLTCQV TFPGAGVTVQ KTIQLNVTYN SQNSTAHVSG
260 270 280 290 300
RVGPGKPRPL ADVVQVAMGE AAIKFLLLGI CFFFLSKRSH TKRVERPATH

MDQAHAVMD
Length:309
Mass (Da):34,345
Last modified:September 27, 2005 - v1
Checksum:i95F17149FA074933
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ157764 mRNA. Translation: AAZ81614.1.
RefSeqiNP_848821.2. NM_178706.5.
UniGeneiMm.44425.

Genome annotation databases

GeneIDi233274.

Similar proteinsi

Entry informationi

Entry nameiQ3Y597_MOUSE
AccessioniPrimary (citable) accession number: Q3Y597
Entry historyiIntegrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: July 5, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)