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Q3Y185 (Q3Y185_ENTFC) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

ErfK/YbiS/YcfS/YnhG family protein EMBL AFK60179.1
Gene names
ORF Names:EfaeDRAFT_1610 EMBL EAN10258.1, HMPREF0351_12555 EMBL AFK60179.1
OrganismEnterococcus faecium DO [Complete proteome] EMBL EAN10258.1
Taxonomic identifier333849 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

Protein attributes

Sequence length466 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3333 Potential EMBL EAN10258.1
Chain34 – 466433 Potential EMBL EAN10258.1
PRO_5000006814

Sites

Binding site4211Sulfate 2 PDB 2HKL
Binding site4401Sulfate 2; via amide nitrogen PDB 2HKL
Binding site4441Sulfate 2 PDB 2HKL

Sequences

Sequence LengthMass (Da)Tools
Q3Y185 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 86336B131FB6E1E1

FASTA46652,056
        10         20         30         40         50         60 
MTRSSHRKKS KHVALLSVLG VLLVLISFYT YRSTYYTKHF LPNTEINGIN VSNLTVEKAN 

        70         80         90        100        110        120 
EKLKEAYSDK KLAIKEDGKV WQEVPKSELG YKDDFTSELS PILNEQNGWT WGMTYVSAAE 

       130        140        150        160        170        180 
KQEIDPVSQN HQKLDTTVQT LTTKLTDLNK DRTPTTDATI EKAGDSFVIK PEVNGNTIDV 

       190        200        210        220        230        240 
DAAVKQLKSA VNSGKDTIEL TEFKEKPKVT SEDSSLKEQL ASMNAIANVK ATYSINGETF 

       250        260        270        280        290        300 
QIPSSDIMSW LTYNDGKVDL DTEQVRQYVT DLGTKYNTST NDTKFKSTKR GEVTVPVGTY 

       310        320        330        340        350        360 
SWTIQTDSET EALKKAILAG QDFTRSPIVQ GGTTADHPLI EDTYIEVDLE NQHMWYYKDG 

       370        380        390        400        410        420 
KVALETDIVS GKPTTPTPAG VFYVWNKEED ATLKGTNDDG TPYESPVNYW MPIDWTGVGI 

       430        440        450        460 
HDSDWQPEYG GDLWKTRGSH GCINTPPSVM KELFGMVEKG TPVLVF 

« Hide

References

[1]DOE Joint Genome Institute
Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DO EMBL EAN10258.1.
[2]"Annotation of the draft genome assembly of Enterococcus faecium DO."
US DOE Joint Genome Institute (JGI-ORNL)
Larimer F., Land M.
Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DO EMBL EAN10258.1.
[3]"Sequencing of the draft genome and assembly of Enterococcus faecium DO."
US DOE Joint Genome Institute (JGI-PGF)
Copeland A., Lucas S., Lapidus A., Barry K., Detter C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P.
Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DO EMBL EAN10258.1.
[4]"Crystal structure of a novel beta-lactam-insensitive peptidoglycan transpeptidase."
Biarrotte-Sorin S., Hugonnet J.E., Delfosse V., Mainardi J.L., Gutmann L., Arthur M., Mayer C.
J. Mol. Biol. 359:533-538(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 217-466.
[5]"Crystal structure of Enterococcus faecium L,D-transpeptidase C442S mutant."
Delfosse V., Hugonnet J.-E., Magnet S., Mainardi J.-L., Arthur M., Mayer C.
Submitted (JUL-2006) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 217-466 IN COMPLEX WITH SULFATE.
[6]"Complete genome sequence of Enterococcus faecium strain TX16 and comparative genomic analysis of Enterococcus faecium genomes."
Qin X., Galloway-Pena J.R., Sillanpaa J., Hyeob Roh J., Nallapareddy S.R., Chowdhury S., Bourgogne A., Choudhury T., Munzy D.M., Buhay C.J., Ding Y., Dugan-Rocha S., Liu W., Kovar C., Sodergren E., Highlander S., Petrosino J.F., Worley K.C. expand/collapse author list , Gibbs R.A., Weinstock G.M., Murray B.E.
BMC Microbiol. 12:135-135(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DO EMBL AFK60179.1.
[7]"Structure of Enterococcus faeciuml,d-transpeptidase acylated by ertapenem provides insight into the inactivation mechanism."
Lecoq L., Dubee V., Triboulet S., Bougault C., Hugonnet J.E., Arthur M., Simorre J.P.
ACS Chem. Biol. 8:1140-1146(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR OF 341-466.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003583 Genomic DNA. Translation: AFK60179.1.
AAAK03000012 Genomic DNA. Translation: EAN10258.1.
RefSeqYP_006377161.1. NC_017960.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZATX-ray2.40A217-466[»]
2HKLX-ray2.60A/B/C217-466[»]
3ZG4NMR-A341-465[»]
3ZGPNMR-A341-466[»]
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSC82.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAFK60179; AFK60179; HMPREF0351_12555.
EAN10258; EAN10258; EfaeDRAFT_1610.
GeneID13001293.
KEGGefu:HMPREF0351_12555.

Organism-specific databases

CMRSearch...

Enzyme and pathway databases

BioCycEFAE333849:GLCV-2634-MONOMER.

Family and domain databases

InterProIPR005490. LD_TPept_cat_dom.
IPR022029. PG_binding_4.
[Graphical view]
PfamPF12229. PG_binding_4. 2 hits.
PF03734. YkuD. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ3Y185.

Entry information

Entry nameQ3Y185_ENTFC
AccessionPrimary (citable) accession number: Q3Y185
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)