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Q3Y185

- Q3Y185_ENTFC

UniProt

Q3Y185 - Q3Y185_ENTFC

Protein
Submitted name:

ErfK/YbiS/YcfS/YnhG

Gene

EfaeDRAFT_1610

Organism
Enterococcus faecium DO
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei421 – 4211Sulfate 2Imported
    Binding sitei440 – 4401Sulfate 2; via amide nitrogenImported
    Binding sitei444 – 4441Sulfate 2Imported

    GO - Molecular functioni

    1. transferase activity Source: InterPro

    Enzyme and pathway databases

    BioCyciEFAE333849:GLCV-2634-MONOMER.

    Protein family/group databases

    MEROPSiC82.001.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ErfK/YbiS/YcfS/YnhGImported
    Submitted name:
    ErfK/YbiS/YcfS/YnhG family proteinImported
    Gene namesi
    ORF Names:EfaeDRAFT_1610Imported, HMPREF0351_12555Imported
    OrganismiEnterococcus faecium DOImported
    Taxonomic identifieri333849 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
    ProteomesiUP000005269: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3333 PotentialImportedAdd
    BLAST
    Chaini34 – 466433 PotentialImportedPRO_5000006814Add
    BLAST

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1ZATX-ray2.40A217-466[»]
    2HKLX-ray2.60A/B/C217-466[»]
    3ZG4NMR-A341-465[»]
    3ZGPNMR-A341-466[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ3Y185.

    Family & Domainsi

    Keywords - Domaini

    SignalImported

    Family and domain databases

    InterProiIPR005490. LD_TPept_cat_dom.
    IPR022029. PG_binding_4.
    [Graphical view]
    PfamiPF12229. PG_binding_4. 2 hits.
    PF03734. YkuD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q3Y185-1 [UniParc]FASTAAdd to Basket

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    MTRSSHRKKS KHVALLSVLG VLLVLISFYT YRSTYYTKHF LPNTEINGIN    50
    VSNLTVEKAN EKLKEAYSDK KLAIKEDGKV WQEVPKSELG YKDDFTSELS 100
    PILNEQNGWT WGMTYVSAAE KQEIDPVSQN HQKLDTTVQT LTTKLTDLNK 150
    DRTPTTDATI EKAGDSFVIK PEVNGNTIDV DAAVKQLKSA VNSGKDTIEL 200
    TEFKEKPKVT SEDSSLKEQL ASMNAIANVK ATYSINGETF QIPSSDIMSW 250
    LTYNDGKVDL DTEQVRQYVT DLGTKYNTST NDTKFKSTKR GEVTVPVGTY 300
    SWTIQTDSET EALKKAILAG QDFTRSPIVQ GGTTADHPLI EDTYIEVDLE 350
    NQHMWYYKDG KVALETDIVS GKPTTPTPAG VFYVWNKEED ATLKGTNDDG 400
    TPYESPVNYW MPIDWTGVGI HDSDWQPEYG GDLWKTRGSH GCINTPPSVM 450
    KELFGMVEKG TPVLVF 466
    Length:466
    Mass (Da):52,056
    Last modified:October 11, 2005 - v1
    Checksum:i86336B131FB6E1E1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003583 Genomic DNA. Translation: AFK60179.1.
    AAAK03000012 Genomic DNA. Translation: EAN10258.1.
    RefSeqiYP_006377161.1. NC_017960.1.

    Genome annotation databases

    EnsemblBacteriaiAFK60179; AFK60179; HMPREF0351_12555.
    EAN10258; EAN10258; EfaeDRAFT_1610.
    GeneIDi13001293.
    KEGGiefu:HMPREF0351_12555.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003583 Genomic DNA. Translation: AFK60179.1 .
    AAAK03000012 Genomic DNA. Translation: EAN10258.1 .
    RefSeqi YP_006377161.1. NC_017960.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1ZAT X-ray 2.40 A 217-466 [» ]
    2HKL X-ray 2.60 A/B/C 217-466 [» ]
    3ZG4 NMR - A 341-465 [» ]
    3ZGP NMR - A 341-466 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi C82.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AFK60179 ; AFK60179 ; HMPREF0351_12555 .
    EAN10258 ; EAN10258 ; EfaeDRAFT_1610 .
    GeneIDi 13001293.
    KEGGi efu:HMPREF0351_12555.

    Enzyme and pathway databases

    BioCyci EFAE333849:GLCV-2634-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q3Y185.

    Family and domain databases

    InterProi IPR005490. LD_TPept_cat_dom.
    IPR022029. PG_binding_4.
    [Graphical view ]
    Pfami PF12229. PG_binding_4. 2 hits.
    PF03734. YkuD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. DOE Joint Genome Institute
      Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DOImported.
    2. "Annotation of the draft genome assembly of Enterococcus faecium DO."
      US DOE Joint Genome Institute (JGI-ORNL)
      Larimer F., Land M.
      Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DOImported.
    3. "Sequencing of the draft genome and assembly of Enterococcus faecium DO."
      US DOE Joint Genome Institute (JGI-PGF)
      Copeland A., Lucas S., Lapidus A., Barry K., Detter C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P.
      Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DOImported.
    4. "Crystal structure of a novel beta-lactam-insensitive peptidoglycan transpeptidase."
      Biarrotte-Sorin S., Hugonnet J.E., Delfosse V., Mainardi J.L., Gutmann L., Arthur M., Mayer C.
      J. Mol. Biol. 359:533-538(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 217-466.
    5. "Crystal structure of Enterococcus faecium L,D-transpeptidase C442S mutant."
      Delfosse V., Hugonnet J.-E., Magnet S., Mainardi J.-L., Arthur M., Mayer C.
      Submitted (JUL-2006) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 217-466.
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DOImported.
    7. "Structure of Enterococcus faeciuml,d-transpeptidase acylated by ertapenem provides insight into the inactivation mechanism."
      Lecoq L., Dubee V., Triboulet S., Bougault C., Hugonnet J.E., Arthur M., Simorre J.P.
      ACS Chem. Biol. 8:1140-1146(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: STRUCTURE BY NMR OF 341-466.

    Entry informationi

    Entry nameiQ3Y185_ENTFC
    AccessioniPrimary (citable) accession number: Q3Y185
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3