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Q3V5Z9 (HXD3_ORYLA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the Antp homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmulticellular organismal development

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Homeobox protein Hox-D3
PRO_0000363947

Regions

DNA binding160 – 21960Homeobox
Motif128 – 1336Antp-type hexapeptide

Sequences

Sequence LengthMass (Da)Tools
Q3V5Z9 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: A7E44CE171E912A5

FASTA39542,794
        10         20         30         40         50         60 
MQKATYYDNS GLFGGYSYPK PDSYSYGPAH QSYPTANIES DYQGPVCPIQ TPAVRPPALK 

        70         80         90        100        110        120 
DTDLNGDCMR QSSSQSSNSG TQAGSISEQQ APPLSASPPS SNSSASQKKK SPSGGASGAA 

       130        140        150        160        170        180 
TPALTKQIFP WMKETRQNSK QKSNNCGEVS DEKSPPGPAS KRVRTAYTSA QLVELEKEFH 

       190        200        210        220        230        240 
FNRYLCRPRR VEMANLLNLT ERQIKIWFQN RRMKYKKDQK SKGLAHSPLG HSPDRSPPLS 

       250        260        270        280        290        300 
GPNHVGYSGQ LQNVNSLSYD APSPPSFAKP QQNMYGLAAY TAPLGGCIPQ QKRYPGSEYE 

       310        320        330        340        350        360 
HHGMQSNGGF ANANLQGSPV YVGGNFVDSM PASGPMFNLG HLPHPSSTSV DYSCAAQIPG 

       370        380        390 
NHHHGPCDPH PTYTDLTSHQ ASQGRIQEAP KLTHL 

« Hide

References

[1]"Organization and structure of hox gene loci in medaka genome and comparison with those of pufferfish and zebrafish genomes."
Kurosawa G., Takamatsu N., Takahashi M., Sumitomo M., Sanaka E., Yamada K., Nishii K., Matsuda M., Asakawa S., Ishiguro H., Miura K., Kurosawa Y., Shimizu N., Kohara Y., Hori H.
Gene 370:75-82(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Hd-rR.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB208013 Genomic DNA. Translation: BAE44287.1.
AB232923 Genomic DNA. Translation: BAE53501.1.

3D structure databases

ProteinModelPortalQ3V5Z9.
SMRQ3V5Z9. Positions 160-219.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGNOG284589.
HOGENOMHOG000252944.
HOVERGENHBG107984.
InParanoidQ3V5Z9.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
InterProIPR025281. DUF4074.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamPF13293. DUF4074. 1 hit.
PF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
PROSITEPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXD3_ORYLA
AccessionPrimary (citable) accession number: Q3V5Z9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: October 11, 2005
Last modified: February 19, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries