Unreviewed, UniProtKB/TrEMBL Q3V4E3 (Q3V4E3_HUMAN)

Names and origin

Protein names

Submitted name:
    cDNA FLJ50870, moderately similar to Endothelial cell-specific molecule 1 EMBL BAG62324.1
Submitted name:
    Endocan EMBL CAJ13737.1

Gene names

Name:

ESM1 EMBL CAJ13737.1

Organism

Homo sapiens (Human) EMBL CAJ13737.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	134 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 IGFBP N-terminal domain. Spearmint SPM000867

Ontologies

Keywords
Domain	Signal
Gene Ontology (GO)
Biological process	regulation of cell growth Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	insulin-like growth factor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	EMBL CAJ13737.1
	Chain	20 – 134	115	endocan EMBL CAJ13737.1		PRO_5000074941

Sequences

	Sequence		Length	Mass (Da)
	Q3V4E3-1 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 93F9A5E8396BD330	FASTA	134	14,513
	10 20 30 40 50 60 MKSVLLLTTL LVPAHLVAAW SNNYAVDCPQ HCDSSECKSS PRCKRTVLDD CGCCRVCAAG 70 80 90 100 110 120 RGETCYRTVS GMDGMKCGPG LRCQPSNGED PFGEEFGICK EHDMASGDGN IVREEVVKEN 130 AAGSPVMRKW LNPR

References

[1]	"Exon 2 of the endocan gene contributes to tumorigenesis and its expression is increased in human lung tumor vascular cells." Depontieu F., Grigoriu B., Scherpereel A., Adam E., Lafitte J.J., Ouatas T., Delehedde M., Lyon M., Copin M.C., Janin A., Tonnel A.B., Tsicopoulos A., Lassalle P. Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK300634 mRNA. Translation: BAG62324.1. AJ973643 mRNA. Translation: CAJ13737.1.
IPI	IPI00651761.
RefSeq	NP_001129076.1.
UniGene	Hs.129944
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000164283. Homo sapiens. [Contig view]
GeneID	11082.
Organism-specific databases
HGNC	HGNC:3466. ESM1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q3V4E3.
Gene expression databases
ArrayExpress	Q3V4E3.
Bgee	Q3V4E3.
Family and domain databases
InterPro	IPR000867. IGFBP-like. [Graphical view]
SMART	SM00121. IB. 1 hit. [Graphical view]
PROSITE	PS51323. IGFBP_N_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q3V4E3_HUMAN

Accession

Primary (citable) accession number: Q3V4E3

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)