Q3V415 (Q3V415_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAE43257.1

Gene names

Name:

Mtmr2 MGI 1924366

Organism

Mus musculus (Mouse) EMBL BAE43257.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	241 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 myotubularin phosphatase domain. SAAS SAAS017906

Ontologies

Gene Ontology (GO)
Biological_process	dendritic spine maintenance Inferred from electronic annotation. Source: Compara inositol phosphate dephosphorylation Inferred from direct assay PubMed 16399794. Source: MGI myelin assembly Inferred from mutant phenotype PubMed 22028665. Source: MGI negative regulation of excitatory postsynaptic membrane potential Inferred from electronic annotation. Source: Compara negative regulation of myelination Inferred from genetic interaction PubMed 22028665. Source: MGI negative regulation of receptor catabolic process Inferred from electronic annotation. Source: Compara negative regulation of receptor internalization Inferred from electronic annotation. Source: Compara neuron development Inferred from genetic interaction PubMed 22028665. Source: MGI phosphatidylinositol dephosphorylation Inferred from direct assay PubMed 16399794. Source: MGI positive regulation of early endosome to late endosome transport Inferred from electronic annotation. Source: Compara protein tetramerization Inferred from physical interaction PubMed 16399794. Source: MGI
Cellular_component	axon Inferred from electronic annotation. Source: Compara cytosol Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: Compara postsynaptic density Inferred from electronic annotation. Source: Compara synaptic membrane Inferred from electronic annotation. Source: Compara synaptic vesicle Inferred from electronic annotation. Source: Compara vacuolar membrane Inferred from direct assay PubMed 16399794. Source: MGI
Molecular_function	phosphatidylinositol phosphate phosphatase activity Inferred from mutant phenotype PubMed 22028665. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	241	1	EMBL BAE43257.1

Sequences

	Sequence		Length	Mass (Da)
	Q3V415 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 04654CE71AACE1DE	FASTA	241	27,468
	10 20 30 40 50 60 MEEPALLPGE NIKDMAKDVT YICPFTGAVR GTLTVTSYRL YFKSMERDPP FVLDASLGVI 70 80 90 100 110 120 SRVEKIGGAS SRGENSYGLE TVCKDIRNLR FAHKPEGRTR RSIFENLMKY AFPVSNGLPL 130 140 150 160 170 180 FAFEYKEVFP ENGWKLYDPL LEYRRQGIPN ESWRITKINE RYELCDTYPA LLVVPANIPD 190 200 210 220 230 240 EELKRVASFR SRGRIPVLSW IHPESQATVT RCSQPMVGVS GKRSKEDEKY LQAIMDSNAQ S

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE43257.1. Tissue: Testis EMBL BAE43257.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE43257.1. Tissue: Testis EMBL BAE43257.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE43257.1. Tissue: Testis EMBL BAE43257.1.
[4]	Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y. Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE43257.1. Tissue: Testis EMBL BAE43257.1.
[5]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE43257.1. Tissue: Testis EMBL BAE43257.1.
[6]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE43257.1. Tissue: Testis EMBL BAE43257.1.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE43257.1. Tissue: Testis EMBL BAE43257.1.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE43257.1. Tissue: Testis EMBL BAE43257.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK020065 mRNA. Translation: BAE43257.1.
IPI	IPI00918927.
UniGene	Mm.210405.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000111316. Q3V415.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc012goc.1. mouse.
Organism-specific databases
MGI	MGI:1924366. Mtmr2.
Phylogenomic databases
HOVERGEN	HBG070742.
InParanoid	Q3V415.
Gene expression databases
ArrayExpress	Q3V415.
Bgee	Q3V415.
Genevestigator	Q3V415.
Family and domain databases
Gene3D	2.30.29.30. 1 hit.
InterPro	IPR004182. GRAM. IPR010569. Myotub-related. IPR017906. Myotubularin_phosphatase_dom. IPR011993. PH_like_dom. [Graphical view]
Pfam	PF02893. GRAM. 1 hit. PF06602. Myotub-related. 1 hit. [Graphical view]
SMART	SM00568. GRAM. 1 hit. [Graphical view]
PROSITE	PS51339. PPASE_MYOTUBULARIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q3V415_MOUSE

Accession

Primary (citable) accession number: Q3V415

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	April 3, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)