Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q3V415 (Q3V415_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Mtmr2 MGI 1924366
OrganismMus musculus (Mouse) EMBL BAE43257.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length241 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains myotubularin phosphatase domain. SAAS SAAS010569

Ontologies

Gene Ontology (GO)
   Biological_processdendritic spine maintenance

Inferred from electronic annotation. Source: Ensembl

dephosphorylation

Inferred from direct assay PubMed 16399794. Source: MGI

inositol phosphate dephosphorylation

Inferred from direct assay PubMed 16399794. Source: MGI

myelin assembly

Inferred from mutant phenotype PubMed 22028665. Source: MGI

negative regulation of excitatory postsynaptic membrane potential

Inferred from electronic annotation. Source: Ensembl

negative regulation of myelination

Inferred from genetic interaction PubMed 22028665. Source: MGI

negative regulation of receptor catabolic process

Inferred from electronic annotation. Source: Ensembl

negative regulation of receptor internalization

Inferred from electronic annotation. Source: Ensembl

neuron development

Inferred from genetic interaction PubMed 22028665. Source: MGI

phosphatidylinositol dephosphorylation

Inferred from direct assay PubMed 16399794. Source: MGI

phosphatidylinositol metabolic process

Inferred from mutant phenotype PubMed 22028665. Source: MGI

positive regulation of early endosome to late endosome transport

Inferred from electronic annotation. Source: Ensembl

protein tetramerization

Inferred from physical interaction PubMed 16399794. Source: MGI

   Cellular_componentaxon

Inferred from electronic annotation. Source: Ensembl

cytoplasm

Inferred from direct assay PubMed 12837694PubMed 16399794. Source: MGI

cytosol

Inferred from electronic annotation. Source: Ensembl

neuronal postsynaptic density

Inferred from electronic annotation. Source: Ensembl

nucleus

Inferred from electronic annotation. Source: Ensembl

synaptic membrane

Inferred from electronic annotation. Source: Ensembl

synaptic vesicle

Inferred from electronic annotation. Source: Ensembl

vacuolar membrane

Inferred from direct assay PubMed 16399794. Source: MGI

   Molecular_functionphosphatidylinositol phosphate phosphatase activity

Inferred from mutant phenotype PubMed 22028665. Source: MGI

protein homodimerization activity

Inferred from physical interaction PubMed 16399794. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue2411 EMBL BAE43257.1

Sequences

Sequence LengthMass (Da)Tools
Q3V415 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 04654CE71AACE1DE

FASTA24127,468
        10         20         30         40         50         60 
MEEPALLPGE NIKDMAKDVT YICPFTGAVR GTLTVTSYRL YFKSMERDPP FVLDASLGVI 

        70         80         90        100        110        120 
SRVEKIGGAS SRGENSYGLE TVCKDIRNLR FAHKPEGRTR RSIFENLMKY AFPVSNGLPL 

       130        140        150        160        170        180 
FAFEYKEVFP ENGWKLYDPL LEYRRQGIPN ESWRITKINE RYELCDTYPA LLVVPANIPD 

       190        200        210        220        230        240 
EELKRVASFR SRGRIPVLSW IHPESQATVT RCSQPMVGVS GKRSKEDEKY LQAIMDSNAQ 


S 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE43257.1.
Tissue: Testis EMBL BAE43257.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE43257.1.
Tissue: Testis EMBL BAE43257.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE43257.1.
Tissue: Testis EMBL BAE43257.1.
[4]Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. expand/collapse author list , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y.
Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE43257.1.
Tissue: Testis EMBL BAE43257.1.
[5]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE43257.1.
Tissue: Testis EMBL BAE43257.1.
[6]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE43257.1.
Tissue: Testis EMBL BAE43257.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE43257.1.
Tissue: Testis EMBL BAE43257.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE43257.1.
Tissue: Testis EMBL BAE43257.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK020065 mRNA. Translation: BAE43257.1.
UniGeneMm.210405.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000111316.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc012goc.1. mouse.

Organism-specific databases

MGIMGI:1924366. Mtmr2.

Phylogenomic databases

HOVERGENHBG070742.
InParanoidQ3V415.

Gene expression databases

BgeeQ3V415.
GenevestigatorQ3V415.

Family and domain databases

Gene3D2.30.29.30. 1 hit.
InterProIPR004182. GRAM.
IPR010569. Myotubularin-like_Pase_dom.
IPR011993. PH_like_dom.
[Graphical view]
PfamPF02893. GRAM. 1 hit.
PF06602. Myotub-related. 1 hit.
[Graphical view]
SMARTSM00568. GRAM. 1 hit.
[Graphical view]
PROSITEPS51339. PPASE_MYOTUBULARIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ3V415_MOUSE
AccessionPrimary (citable) accession number: Q3V415
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)