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Q3V318 (Q3V318_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Trpv1 MGI 1341787
OrganismMus musculus (Mouse) EMBL BAE20689.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length839 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 4 ANK repeats. RuleBase RU003321

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainANK repeat RuleBase RU003321 SAAS SAAS005821
Repeat RuleBase RU003536
Transmembrane RuleBase RU003378
   Molecular functionIon channel RuleBase RU003378
Gene Ontology (GO)
   Biological_processbehavioral response to pain

Inferred from mutant phenotype PubMed 17767493PubMed 18272658. Source: MGI

calcium ion transmembrane transport

Inferred from mutant phenotype PubMed 10764638PubMed 17767493. Source: GOC

calcium ion transport

Inferred from direct assay PubMed 17194758. Source: MGI

catagen

Inferred from mutant phenotype PubMed 16645591. Source: MGI

cation transport

Inferred from sequence alignment PubMed 15883036. Source: MGI

detection of chemical stimulus involved in sensory perception of pain

Inferred from direct assay PubMed 18272293. Source: MGI

diet induced thermogenesis

Inferred from mutant phenotype PubMed 12161756. Source: MGI

fever generation

Inferred from mutant phenotype PubMed 15763167. Source: MGI

ion transmembrane transport

Inferred from direct assay PubMed 15194687. Source: GOC

lipid metabolic process

Inferred from mutant phenotype PubMed 12161756. Source: MGI

peptide secretion

Inferred from mutant phenotype PubMed 18172555. Source: MGI

response to heat

Inferred from mutant phenotype PubMed 10764638. Source: MGI

response to organonitrogen compound

Inferred from mutant phenotype PubMed 17767493. Source: MGI

response to pH

Inferred from mutant phenotype PubMed 10764638. Source: MGI

response to pain

Inferred from direct assay PubMed 18272293. Source: MGI

sensory perception of mechanical stimulus

Inferred from mutant phenotype PubMed 12161756. Source: MGI

sensory perception of pain

Inferred from mutant phenotype PubMed 10764638. Source: MGI

smooth muscle contraction involved in micturition

Inferred from mutant phenotype PubMed 12161756. Source: MGI

temperature homeostasis

Inferred from mutant phenotype PubMed 10764638. Source: MGI

urinary bladder smooth muscle contraction

Inferred from mutant phenotype PubMed 12161756. Source: MGI

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

membrane

Inferred from sequence alignment PubMed 15883036. Source: MGI

neuron projection

Inferred from direct assay PubMed 11466438. Source: MGI

   Molecular_functioncalcium channel activity

Inferred from mutant phenotype PubMed 10764638PubMed 17767493. Source: MGI

cation channel activity

Inferred from sequence alignment PubMed 15883036. Source: MGI

ion channel activity

Inferred from direct assay PubMed 15194687. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q3V318 [UniParc].

Last modified October 11, 2005. Version 1.
Checksum: 0D5A27D8C0665F8A

FASTA83994,962
        10         20         30         40         50         60 
MEKWASLDSD ESEPPAQENS CPDPPDRDPN SKPPPAKPHI FATRSRTRLF GKGDSEEASP 

        70         80         90        100        110        120 
MDCPYEEGGL ASCPIITVSS VVTLQRSVDG PTCLRQTSQD SVSTGVETPP RLYDRRSIFD 

       130        140        150        160        170        180 
AVAQSNCQEL ESLLSFLQKS KKRLTDSEFK DPETGKTCLL KAMLNLHNGQ NDTIALLLDI 

       190        200        210        220        230        240 
ARKTDSLKQF VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AANGDFFKKT 

       250        260        270        280        290        300 
KGRPGFYFGE LPLSLAACTN QLAIVKFLLQ NSWQPADISA RDSVGNTVLH ALVEVADNTA 

       310        320        330        340        350        360 
DNTKFVTNMY NEILILGAKL HPTLKLEELT NKKGLTPLAL AASSGKIGVL AYILQREIHE 

       370        380        390        400        410        420 
PECRHLSRKF TEWAYGPVHS SLYDLSCIDT CEKNSVLEVI AYSSSETPNR HDMLLVEPLN 

       430        440        450        460        470        480 
RLLQDKWDRF VKRIFYFNFF VYCLYMIVFT TAAYYRPVEG LPPYKLNNTV GDYFRVTGEI 

       490        500        510        520        530        540 
LSVSGGVYFF FRGIQYFLQR RPSLKSLFVD SYSEILFFVQ SLFMLVSVVL YFSHRKEYVA 

       550        560        570        580        590        600 
SMVFSLAMGW TNMLYYTRGF QQMGIYAVMI EKMILRDLCR FMFVYLVFLF GFSTAVVTLI 

       610        620        630        640        650        660 
EDGKNNSLPV ESPPHKCRGS ACRPGNSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF 

       670        680        690        700        710        720 
IILLLAYVIL TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA 

       730        740        750        760        770        780 
FRSGKLLQVG FTPDGKDDFR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS 

       790        800        810        820        830 
GRVSGRNWKN FALVPLLRDA STRDRHSTQP EEVQLKHYTG SLKPEDAEVF KDSMAPGEK 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE20689.1.
Tissue: Spinal ganglion EMBL BAE20689.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE20689.1.
Tissue: Spinal ganglion EMBL BAE20689.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE20689.1.
Tissue: Spinal ganglion EMBL BAE20689.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE20689.1.
Tissue: Spinal ganglion EMBL BAE20689.1.
[5]Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K. expand/collapse author list , Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE20689.1.
Tissue: Spinal ganglion EMBL BAE20689.1.
[6]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE20689.1.
Tissue: Spinal ganglion EMBL BAE20689.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE20689.1.
Tissue: Spinal ganglion EMBL BAE20689.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE20689.1.
Tissue: Spinal ganglion EMBL BAE20689.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK051315 mRNA. Translation: BAE20689.1.
UniGeneMm.447485.

3D structure databases

ProteinModelPortalQ3V318.
SMRQ3V318. Positions 112-359.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:1341787. Trpv1.

Phylogenomic databases

HOVERGENHBG054085.
InParanoidQ3V318.

Gene expression databases

GenevestigatorQ3V318.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR005821. Ion_trans_dom.
IPR004729. TRP_channel.
IPR024862. TRPV.
IPR008347. TRPV1-4_channel.
IPR024863. TRPV1_channel.
[Graphical view]
PANTHERPTHR10582. PTHR10582. 1 hit.
PTHR10582:SF5. PTHR10582:SF5. 1 hit.
PfamPF12796. Ank_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSPR01768. TRPVRECEPTOR.
SMARTSM00248. ANK. 4 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
TIGRFAMsTIGR00870. trp. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ3V318_MOUSE
AccessionPrimary (citable) accession number: Q3V318
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)