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Q3V245

- Q3V245_MOUSE

UniProt

Q3V245 - Q3V245_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Clu

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cell morphogenesis Source: Ensembl
  2. central nervous system myelin maintenance Source: Ensembl
  3. chaperone-mediated protein complex assembly Source: Ensembl
  4. chaperone-mediated protein folding Source: Ensembl
  5. intrinsic apoptotic signaling pathway Source: Ensembl
  6. microglial cell activation Source: Ensembl
  7. microglial cell proliferation Source: Ensembl
  8. negative regulation of beta-amyloid formation Source: Ensembl
  9. negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
  10. negative regulation of protein homooligomerization Source: Ensembl
  11. positive regulation of apoptotic process Source: Ensembl
  12. positive regulation of intrinsic apoptotic signaling pathway Source: Ensembl
  13. positive regulation of neurofibrillary tangle assembly Source: Ensembl
  14. positive regulation of neuron death Source: Ensembl
  15. positive regulation of NF-kappaB transcription factor activity Source: Ensembl
  16. positive regulation of nitric oxide biosynthetic process Source: Ensembl
  17. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
  18. positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: Ensembl
  19. positive regulation of tau-protein kinase activity Source: Ensembl
  20. positive regulation of tumor necrosis factor production Source: Ensembl
  21. protein import Source: Ensembl
  22. protein stabilization Source: Ensembl
  23. regulation of beta-amyloid clearance Source: Ensembl
  24. regulation of neuronal signal transduction Source: Ensembl
  25. response to misfolded protein Source: Ensembl
  26. response to virus Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:CluImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88423. Clu.

Subcellular locationi

GO - Cellular componenti

  1. apical dendrite Source: Ensembl
  2. blood microparticle Source: Ensembl
  3. extracellular matrix Source: Ensembl
  4. extracellular vesicular exosome Source: Ensembl
  5. mitochondrion Source: Ensembl
  6. neurofibrillary tangle Source: Ensembl
  7. perinuclear region of cytoplasm Source: Ensembl
  8. spherical high-density lipoprotein particle Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ3V245.
ExpressionAtlasiQ3V245. baseline and differential.
GenevestigatoriQ3V245.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022616.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000111799.

Family and domain databases

InterProiIPR016016. Clusterin.
IPR000753. Clusterin-like.
[Graphical view]
PANTHERiPTHR10970:SF1. PTHR10970:SF1. 1 hit.
PfamiPF01093. Clusterin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3V245-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKILLLCVAL LLIWDNGMVL GEQEVSDNEL QELSTQGSRY INKEIQNAVQ
60 70
GVKHIKTLIE KTNAERKSLL NSLEEA
Length:76
Mass (Da):8,566
Last modified:October 11, 2005 - v1
Checksum:iC719C9DB39D82A99
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei76 – 761Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK132030 mRNA. Translation: BAE20954.1.
UniGeneiMm.200608.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK132030 mRNA. Translation: BAE20954.1 .
UniGenei Mm.200608.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000022616.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:88423. Clu.

Phylogenomic databases

HOGENOMi HOG000111799.

Miscellaneous databases

ChiTaRSi CLU. mouse.
SOURCEi Search...

Gene expression databases

Bgeei Q3V245.
ExpressionAtlasi Q3V245. baseline and differential.
Genevestigatori Q3V245.

Family and domain databases

InterProi IPR016016. Clusterin.
IPR000753. Clusterin-like.
[Graphical view ]
PANTHERi PTHR10970:SF1. PTHR10970:SF1. 1 hit.
Pfami PF01093. Clusterin. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HippocampusImported.

Entry informationi

Entry nameiQ3V245_MOUSE
AccessioniPrimary (citable) accession number: Q3V245
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)