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Protein
Submitted name:

Uncharacterized protein

Gene

Nr1h4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi135 – 210Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Nr1h4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1352464 Nr1h4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Chemistry databases

GuidetoPHARMACOLOGYi603

PTM / Processingi

Proteomic databases

PRIDEiQ3V1T8

Expressioni

Gene expression databases

BgeeiENSMUSG00000047638
ExpressionAtlasiQ3V1T8 baseline and differential
GenevisibleiQ3V1T8 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ3V1T8
SMRiQ3V1T8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini135 – 210Nuclear receptorInterPro annotationAdd BLAST76
Domaini260 – 484NR LBDInterPro annotationAdd BLAST225

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili209 – 229Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
HOVERGENiHBG108655

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001728 ThyrH_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
PR00546 THYROIDHORMR
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3V1T8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVMQFQGLEN PIQISLHHSH RLSGFVPEGM SVKPAKGMLT EHAAGPLGQN
60 70 80 90 100
LDLESYSPYN NVPFPQVQPQ ISSSSYYSNL GFYPQQPEDW YSPGIYELRR
110 120 130 140 150
MPAETGYQGE TEVSEMPVTK KPRMAAASAG RIKGDELCVV CGDRASGYHY
160 170 180 190 200
NALTCEGCKG FFRRSITKNA VYKCKNGGNC VMDMYMRRKC QECRLRKCKE
210 220 230 240 250
MGMLAECLLT EIQCKSKRLR KNVKQHADQT ANEDDSEGRD LRQVTSTTKF
260 270 280 290 300
CREKTELTAD QQTLLDYIMD SYNKQRMPQE ITNKILKEEF SAEENFLILT
310 320 330 340 350
EMATSHVQIL VEFTKKLPGF QTLDHEDQIA LLKGSAVEAM FLRSAEIFNK
360 370 380 390 400
KLPAGHADLL EERIRKSGIS DEYITPMFSF YKSVGELKMT QEEYALLTAI
410 420 430 440 450
VILSPDRQYI KDREAVEKLQ EPLLDVLQKL CKMYQPENPQ HFACLLGRLT
460 470 480
ELRTFNHHHA EMLMSWRVND HKFTPLLCEI WDVQ
Length:484
Mass (Da):55,542
Last modified:October 11, 2005 - v1
Checksum:i06B56494305A438A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK132255 mRNA Translation: BAE21061.1
RefSeqiNP_033134.2, NM_009108.2
UniGeneiMm.3095

Genome annotation databases

GeneIDi20186
UCSCiuc007gsf.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ3V1T8_MOUSE
AccessioniPrimary (citable) accession number: Q3V1T8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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