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Protein
Submitted name:

Putative uncharacterized protein

Gene

Foxg1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. axon midline choice point recognition Source: MGI
  2. cell morphogenesis involved in neuron differentiation Source: MGI
  3. central nervous system neuron development Source: MGI
  4. cerebral cortex development Source: MGI
  5. dorsal/ventral pattern formation Source: MGI
  6. forebrain development Source: MGI
  7. inner ear morphogenesis Source: MGI
  8. negative regulation of neuron differentiation Source: MGI
  9. negative regulation of transcription, DNA-templated Source: MGI
  10. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  11. neurogenesis Source: MGI
  12. neuron fate determination Source: MGI
  13. positive regulation of cell cycle Source: MGI
  14. positive regulation of neuroblast proliferation Source: MGI
  15. positive regulation of neuron differentiation Source: MGI
  16. pyramidal neuron migration Source: MGI
  17. regulation of cell cycle Source: MGI
  18. regulation of gene expression Source: MGI
  19. regulation of mitotic cell cycle Source: MGI
  20. regulation of neural precursor cell proliferation Source: MGI
  21. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Foxg1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1347464. Foxg1.

Subcellular locationi

  1. Nucleus SAAS annotation

GO - Cellular componenti

  1. nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiQ3V1Q8.

Expressioni

Gene expression databases

BgeeiQ3V1Q8.
ExpressionAtlasiQ3V1Q8. baseline and differential.
GenevestigatoriQ3V1Q8.

Structurei

3D structure databases

ProteinModelPortaliQ3V1Q8.
SMRiQ3V1Q8. Positions 173-261.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG051645.
KOiK09385.
OMAiYPSHPMS.
PhylomeDBiQ3V1Q8.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS_1.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3V1Q8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDMGDRKEV KMIPKSSFSI NSLVPEAVQN DNHHASHGHH NSHHPQHHHH
60 70 80 90 100
HHHHHHPPPP APQPPPPPPQ QQQQQPPPAP QPPQARGAPA ADDDKGPQPL
110 120 130 140 150
LLPPSTALDG AKADALGAKG EPGGGPAELA PVGPDEKEKG AGAGGEEKKG
160 170 180 190 200
AGEGGKDGEG GKEGDKKNGK YEKPPFSYNA LIMMAIRQSP EKRLTLNGIY
210 220 230 240 250
EFIMKNFPYY RENKQGWQNS IRHNLSLNKC FVKVPRHYDD PGKGNYWMLD
260 270 280 290 300
PSSDDVFIGG TTGKLRRRST TSRAKLAFKR GARLTSTGLT FMDRAGSLYW
310 320 330 340 350
PMSPFLSLHH PRASSTLSYN GTTSAYPSHP MPYSSVLTQN SLGNNHSFST
360 370 380 390 400
ANGLSVDRLV NGEIPYATHH LTAAALAASV PCGLSVPCSG TYSLNPCSVN
410 420 430 440 450
LLAGQTSYFF PHVPHPSMTS QTSTSMSARA ASSSTSPQAP STLPCESLRP
460 470 480
SLPSFTTGLS GGLSDYFTHQ NQGSSSNPLI H
Length:481
Mass (Da):51,625
Last modified:October 11, 2005 - v1
Checksum:iFF6786C3513AB452
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK132305 mRNA. Translation: BAE21092.1.
RefSeqiNP_001153584.1. NM_001160112.1.
NP_032267.1. NM_008241.2.
UniGeneiMm.4704.

Genome annotation databases

GeneIDi15228.
KEGGimmu:15228.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK132305 mRNA. Translation: BAE21092.1.
RefSeqiNP_001153584.1. NM_001160112.1.
NP_032267.1. NM_008241.2.
UniGeneiMm.4704.

3D structure databases

ProteinModelPortaliQ3V1Q8.
SMRiQ3V1Q8. Positions 173-261.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ3V1Q8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15228.
KEGGimmu:15228.

Organism-specific databases

CTDi2290.
MGIiMGI:1347464. Foxg1.

Phylogenomic databases

HOVERGENiHBG051645.
KOiK09385.
OMAiYPSHPMS.
PhylomeDBiQ3V1Q8.

Miscellaneous databases

ChiTaRSiFoxg1. mouse.
NextBioi287819.
SOURCEiSearch...

Gene expression databases

BgeeiQ3V1Q8.
ExpressionAtlasiQ3V1Q8. baseline and differential.
GenevestigatoriQ3V1Q8.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS_1.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
[Graphical view]
PROSITEiPS00657. FORK_HEAD_1. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: HeadImported.

Entry informationi

Entry nameiQ3V1Q8_MOUSE
AccessioniPrimary (citable) accession number: Q3V1Q8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: April 1, 2015
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.