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Q3V122

- Q3V122_MOUSE

UniProt

Q3V122 - Q3V122_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Mcm7

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent DNA helicase activity Source: Ensembl
  3. single-stranded DNA binding Source: MGI

GO - Biological processi

  1. cell proliferation Source: MGI
  2. cellular response to DNA damage stimulus Source: Ensembl
  3. cellular response to epidermal growth factor stimulus Source: Ensembl
  4. DNA replication initiation Source: InterPro
  5. DNA unwinding involved in DNA replication Source: MGI
  6. regulation of phosphorylation Source: Ensembl
  7. response to drug Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

HelicaseSAAS annotation, Hydrolase

Keywords - Ligandi

ATP-binding, DNA-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Mcm7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1298398. Mcm7.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. MCM complex Source: InterPro
  3. nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiQ3V122.

Expressioni

Gene expression databases

BgeeiQ3V122.
ExpressionAtlasiQ3V122. baseline and differential.
GenevestigatoriQ3V122.

Interactioni

Protein-protein interaction databases

IntActiQ3V122. 3 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ3V122.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MCM family.UniRule annotation
Contains MCM domain.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000224125.
HOVERGENiHBG000741.
PhylomeDBiQ3V122.

Family and domain databases

Gene3Di2.40.50.140. 2 hits.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR008050. MCM7.
IPR018525. MCM_CS.
IPR001208. MCM_DNA-dep_ATPase.
IPR027925. MCM_N.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11630:SF26. PTHR11630:SF26. 1 hit.
PfamiPF00493. MCM. 1 hit.
PF14551. MCM_N. 1 hit.
[Graphical view]
PRINTSiPR01657. MCMFAMILY.
PR01663. MCMPROTEIN7.
SMARTiSM00382. AAA. 1 hit.
SM00350. MCM. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00847. MCM_1. 1 hit.
PS50051. MCM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3V122-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALKDYAIEK EKVKKFLQEF YYENELGKKQ FKYGTQLVHL AHREQVALYV
60 70 80 90 100
DLDDIAEDDP ELVDSICENA KRYSRLFGDV VQELLPEYKE KEVVNKDVLD
110 120 130 140 150
VYIEHRLMME QRSRDPGAVR NPQNQYPSEL MRRFELYFRG PSSSKPRVIR
160 170 180 190 200
EVRADSVGKL LTVRGIVTRV SEVKPRMVVA TYTCDQCGAE TYQPIQSPTF
210 220 230 240 250
MPLIMCPSQE CQTNRSGGRL YLQTRGSKFV KFQEMKIQEH SDQVPVGNIP
260 270 280 290 300
RSITVVLEGE NTRIAQPGDH VSVTGIFLPV LRTGFQQMAQ GLLSETYLEA
310 320 330 340 350
HWIVKMTKSD DDVSGAGELS SEELKQIAEE DFYEKLAASI APEIYGHEDV
360 370 380 390 400
KKALLLLLLV GGVDQSPQGM KIRGNIHICL MGDPGVAKSQ LLSYIDRLAP
410 420 430 440 450
RSQYTTGRGS SGVGLTAAVL RDSVSGELTL EGGALVLADQ GVCCIDEFDK
460 470 480 490 500
MAEADRTAIH EVMEQQTISI AKAGILTTLN ARCSILAAAN PAYGRYNPRR
510 520 530 540 550
SLEQNVQLPA ALLSRFDLLW LIQDRPDRDN DLRLAQHITY VHQHSRQPPA
560 570 580 590 600
QFEPLDMKLM RRYIAMCHER QPTVPESLAD YITAAYVEMR REARASKDAT
610 620 630 640 650
YTSARTLLAI LRLSTALARL RMVDIVEKED VNEAIRLMEM SKDSLLGEKG
660 670 680 690 700
QTARTQRPAD VIFATIRELV SRGRSVHFSE AEQRCISRGF TPAQFQAALD
710 720
EYEELNVWQV NTSRTRITFV
Length:720
Mass (Da):81,324
Last modified:October 11, 2005 - v1
Checksum:i2829CEEC115713BD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK132748 mRNA. Translation: BAE21331.1.
UniGeneiMm.378965.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK132748 mRNA. Translation: BAE21331.1 .
UniGenei Mm.378965.

3D structure databases

ProteinModelPortali Q3V122.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q3V122. 3 interactions.

Proteomic databases

PRIDEi Q3V122.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:1298398. Mcm7.

Phylogenomic databases

HOGENOMi HOG000224125.
HOVERGENi HBG000741.
PhylomeDBi Q3V122.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q3V122.
ExpressionAtlasi Q3V122. baseline and differential.
Genevestigatori Q3V122.

Family and domain databases

Gene3Di 2.40.50.140. 2 hits.
3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR008050. MCM7.
IPR018525. MCM_CS.
IPR001208. MCM_DNA-dep_ATPase.
IPR027925. MCM_N.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR11630:SF26. PTHR11630:SF26. 1 hit.
Pfami PF00493. MCM. 1 hit.
PF14551. MCM_N. 1 hit.
[Graphical view ]
PRINTSi PR01657. MCMFAMILY.
PR01663. MCMPROTEIN7.
SMARTi SM00382. AAA. 1 hit.
SM00350. MCM. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEi PS00847. MCM_1. 1 hit.
PS50051. MCM_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ3V122_MOUSE
AccessioniPrimary (citable) accession number: Q3V122
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: October 29, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)