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Q3V122

- Q3V122_MOUSE

UniProt

Q3V122 - Q3V122_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Mcm7

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + H2O = ADP + phosphate.SAAS annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. ATP-dependent DNA helicase activity Source: Ensembl
    3. protein binding Source: MGI
    4. single-stranded DNA binding Source: MGI

    GO - Biological processi

    1. cell proliferation Source: MGI
    2. cellular response to DNA damage stimulus Source: Ensembl
    3. cellular response to epidermal growth factor stimulus Source: Ensembl
    4. DNA replication initiation Source: InterPro
    5. DNA unwinding involved in DNA replication Source: MGI
    6. regulation of phosphorylation Source: Ensembl
    7. response to drug Source: Ensembl

    Keywords - Molecular functioni

    HelicaseSAAS annotation, Hydrolase

    Keywords - Ligandi

    ATP-binding, DNA-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Mcm7Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1298398. Mcm7.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Ensembl
    2. MCM complex Source: InterPro
    3. nucleus Source: MGI

    Keywords - Cellular componenti

    NucleusSAAS annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiQ3V122.

    Expressioni

    Gene expression databases

    ArrayExpressiQ3V122.
    BgeeiQ3V122.
    GenevestigatoriQ3V122.

    Interactioni

    Protein-protein interaction databases

    IntActiQ3V122. 3 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3V122.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MCM family.UniRule annotation
    Contains MCM domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000224125.
    HOVERGENiHBG000741.
    InParanoidiQ3V122.
    PhylomeDBiQ3V122.

    Family and domain databases

    Gene3Di2.40.50.140. 2 hits.
    3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR008050. MCM7.
    IPR018525. MCM_CS.
    IPR001208. MCM_DNA-dep_ATPase.
    IPR027925. MCM_N.
    IPR012340. NA-bd_OB-fold.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR11630:SF26. PTHR11630:SF26. 1 hit.
    PfamiPF00493. MCM. 1 hit.
    PF14551. MCM_N. 1 hit.
    [Graphical view]
    PRINTSiPR01657. MCMFAMILY.
    PR01663. MCMPROTEIN7.
    SMARTiSM00382. AAA. 1 hit.
    SM00350. MCM. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 2 hits.
    SSF52540. SSF52540. 1 hit.
    PROSITEiPS00847. MCM_1. 1 hit.
    PS50051. MCM_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3V122-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALKDYAIEK EKVKKFLQEF YYENELGKKQ FKYGTQLVHL AHREQVALYV    50
    DLDDIAEDDP ELVDSICENA KRYSRLFGDV VQELLPEYKE KEVVNKDVLD 100
    VYIEHRLMME QRSRDPGAVR NPQNQYPSEL MRRFELYFRG PSSSKPRVIR 150
    EVRADSVGKL LTVRGIVTRV SEVKPRMVVA TYTCDQCGAE TYQPIQSPTF 200
    MPLIMCPSQE CQTNRSGGRL YLQTRGSKFV KFQEMKIQEH SDQVPVGNIP 250
    RSITVVLEGE NTRIAQPGDH VSVTGIFLPV LRTGFQQMAQ GLLSETYLEA 300
    HWIVKMTKSD DDVSGAGELS SEELKQIAEE DFYEKLAASI APEIYGHEDV 350
    KKALLLLLLV GGVDQSPQGM KIRGNIHICL MGDPGVAKSQ LLSYIDRLAP 400
    RSQYTTGRGS SGVGLTAAVL RDSVSGELTL EGGALVLADQ GVCCIDEFDK 450
    MAEADRTAIH EVMEQQTISI AKAGILTTLN ARCSILAAAN PAYGRYNPRR 500
    SLEQNVQLPA ALLSRFDLLW LIQDRPDRDN DLRLAQHITY VHQHSRQPPA 550
    QFEPLDMKLM RRYIAMCHER QPTVPESLAD YITAAYVEMR REARASKDAT 600
    YTSARTLLAI LRLSTALARL RMVDIVEKED VNEAIRLMEM SKDSLLGEKG 650
    QTARTQRPAD VIFATIRELV SRGRSVHFSE AEQRCISRGF TPAQFQAALD 700
    EYEELNVWQV NTSRTRITFV 720
    Length:720
    Mass (Da):81,324
    Last modified:October 11, 2005 - v1
    Checksum:i2829CEEC115713BD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK132748 mRNA. Translation: BAE21331.1.
    UniGeneiMm.378965.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK132748 mRNA. Translation: BAE21331.1 .
    UniGenei Mm.378965.

    3D structure databases

    ProteinModelPortali Q3V122.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q3V122. 3 interactions.

    Proteomic databases

    PRIDEi Q3V122.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1298398. Mcm7.

    Phylogenomic databases

    HOGENOMi HOG000224125.
    HOVERGENi HBG000741.
    InParanoidi Q3V122.
    PhylomeDBi Q3V122.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3V122.
    Bgeei Q3V122.
    Genevestigatori Q3V122.

    Family and domain databases

    Gene3Di 2.40.50.140. 2 hits.
    3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR008050. MCM7.
    IPR018525. MCM_CS.
    IPR001208. MCM_DNA-dep_ATPase.
    IPR027925. MCM_N.
    IPR012340. NA-bd_OB-fold.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR11630:SF26. PTHR11630:SF26. 1 hit.
    Pfami PF00493. MCM. 1 hit.
    PF14551. MCM_N. 1 hit.
    [Graphical view ]
    PRINTSi PR01657. MCMFAMILY.
    PR01663. MCMPROTEIN7.
    SMARTi SM00382. AAA. 1 hit.
    SM00350. MCM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 2 hits.
    SSF52540. SSF52540. 1 hit.
    PROSITEi PS00847. MCM_1. 1 hit.
    PS50051. MCM_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.

    Entry informationi

    Entry nameiQ3V122_MOUSE
    AccessioniPrimary (citable) accession number: Q3V122
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)