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Protein
Submitted name:

Pygopus 2

Gene

Pygo2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • chromatin binding Source: MGI
  • histone acetyltransferase regulator activity Source: MGI
  • histone binding Source: MGI
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • brain development Source: MGI
  • canonical Wnt signaling pathway Source: MGI
  • developmental growth Source: MGI
  • in utero embryonic development Source: MGI
  • kidney development Source: MGI
  • lens development in camera-type eye Source: MGI
  • mammary gland development Source: MGI
  • positive regulation of chromatin binding Source: MGI
  • post-embryonic development Source: MGI
  • regulation of histone H3-K4 methylation Source: MGI
  • regulation of mammary gland epithelial cell proliferation Source: MGI
  • roof of mouth development Source: MGI
  • spermatid development Source: MGI
  • spermatid nucleus differentiation Source: MGI
  • Wnt signaling pathway Source: MGI

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-201722 Formation of the beta-catenin:TCF transactivating complex
R-MMU-3769402 Deactivation of the beta-catenin transactivating complex

Names & Taxonomyi

Protein namesi
Submitted name:
Pygopus 2Imported
Gene namesi
Name:Pygo2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1916161 Pygo2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000047824

Interactioni

GO - Molecular functioni

  • histone binding Source: MGI

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini289 – 347PHD-typeInterPro annotationAdd BLAST59

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IKQ3 Eukaryota
ENOG41128HN LUCA
GeneTreeiENSGT00530000063948
HOGENOMiHOG000001580
HOVERGENiHBG053774
TreeFamiTF333020

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3V113-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSPEKKRRK SNTQGPAYSH LTEFAPPPTP MVDHLVASNP FEDDFGAPKV
60 70 80 90 100
GGAGPPFLGS PVPFGGFRVQ GGMAGQVPPG YGTGGGGGPQ PLRRQPPPFP
110 120 130 140 150
PNPMGPAFNM PPQGPGYPPP GNMNFPSQPF NQSLGQNFSP PGGQVMPGPV
160 170 180 190 200
GGFGPMISPT MGQPPRGELG PPPLPQRFTQ PGAPFGPSLQ RPGQGLPSLP
210 220 230 240 250
PNTSPFPGPD PGFPGPGGED GGKPLNPPAP TAFPQEPHSG SPAAAVNGNQ
260 270 280 290 300
PSFPPSSSGR GGGTPDANSL APPGKAGGGS GPQPPPGLVY PCGACRSEVN
310 320 330 340 350
DDQDAILCEA SCQKWFHREC TGMTESAYGL LTTEASAVWA CDLCLKTKEI
360
QSVYIREGMG QLVAANDG
Length:368
Mass (Da):37,537
Last modified:October 11, 2005 - v1
Checksum:iC9DB6C27B12979E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC171273 Genomic DNA No translation available.
AK132759 mRNA Translation: BAE21340.1
RefSeqiNP_001280692.1, NM_001293763.1
NP_001280695.1, NM_001293766.1
NP_001280696.1, NM_001293767.1
NP_081145.1, NM_026869.3
XP_006502067.1, XM_006502004.3
UniGeneiMm.22521
Mm.487671

Genome annotation databases

EnsembliENSMUST00000107413; ENSMUSP00000103036; ENSMUSG00000047824
GeneIDi68911
KEGGimmu:68911
UCSCiuc008pzp.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ3V113_MOUSE
AccessioniPrimary (citable) accession number: Q3V113
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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