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Protein
Submitted name:

Protein Pygo2

Gene

Pygo2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chromatin binding Source: MGI
  2. histone acetyltransferase regulator activity Source: MGI
  3. histone binding Source: MGI
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. brain development Source: MGI
  2. canonical Wnt signaling pathway Source: MGI
  3. developmental growth Source: MGI
  4. in utero embryonic development Source: MGI
  5. kidney development Source: MGI
  6. lens development in camera-type eye Source: MGI
  7. mammary gland development Source: MGI
  8. palate development Source: MGI
  9. positive regulation of chromatin binding Source: MGI
  10. post-embryonic development Source: MGI
  11. regulation of histone acetylation Source: GOC
  12. regulation of histone H3-K4 methylation Source: MGI
  13. regulation of mammary gland epithelial cell proliferation Source: MGI
  14. spermatid development Source: MGI
  15. spermatid nucleus differentiation Source: MGI
  16. Wnt signaling pathway Source: MGI
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiREACT_216539. formation of the beta-catenin:TCF transactivating complex.
REACT_219771. deactivation of the beta-catenin transactivating complex.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Pygo2Imported
Gene namesi
Name:Pygo2Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 3

Organism-specific databases

MGIiMGI:1916161. Pygo2.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ3V113.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000053672.

Structurei

3D structure databases

ProteinModelPortaliQ3V113.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiNOG72798.
GeneTreeiENSGT00530000063948.
HOGENOMiHOG000001580.
HOVERGENiHBG053774.
TreeFamiTF333020.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00628. PHD. 1 hit.
[Graphical view]
SMARTiSM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3V113-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSPEKKRRK SNTQGPAYSH LTEFAPPPTP MVDHLVASNP FEDDFGAPKV
60 70 80 90 100
GGAGPPFLGS PVPFGGFRVQ GGMAGQVPPG YGTGGGGGPQ PLRRQPPPFP
110 120 130 140 150
PNPMGPAFNM PPQGPGYPPP GNMNFPSQPF NQSLGQNFSP PGGQVMPGPV
160 170 180 190 200
GGFGPMISPT MGQPPRGELG PPPLPQRFTQ PGAPFGPSLQ RPGQGLPSLP
210 220 230 240 250
PNTSPFPGPD PGFPGPGGED GGKPLNPPAP TAFPQEPHSG SPAAAVNGNQ
260 270 280 290 300
PSFPPSSSGR GGGTPDANSL APPGKAGGGS GPQPPPGLVY PCGACRSEVN
310 320 330 340 350
DDQDAILCEA SCQKWFHREC TGMTESAYGL LTTEASAVWA CDLCLKTKEI
360
QSVYIREGMG QLVAANDG
Length:368
Mass (Da):37,537
Last modified:October 11, 2005 - v1
Checksum:iC9DB6C27B12979E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC171273 Genomic DNA. No translation available.
AK132759 mRNA. Translation: BAE21340.1.
RefSeqiNP_001280692.1. NM_001293763.1.
NP_001280695.1. NM_001293766.1.
NP_001280696.1. NM_001293767.1.
NP_081145.1. NM_026869.3.
XP_006502067.1. XM_006502004.1.
UniGeneiMm.22521.
Mm.487671.

Genome annotation databases

EnsembliENSMUST00000107413; ENSMUSP00000103036; ENSMUSG00000047824.
GeneIDi68911.
KEGGimmu:68911.
UCSCiuc008pzp.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC171273 Genomic DNA. No translation available.
AK132759 mRNA. Translation: BAE21340.1.
RefSeqiNP_001280692.1. NM_001293763.1.
NP_001280695.1. NM_001293766.1.
NP_001280696.1. NM_001293767.1.
NP_081145.1. NM_026869.3.
XP_006502067.1. XM_006502004.1.
UniGeneiMm.22521.
Mm.487671.

3D structure databases

ProteinModelPortaliQ3V113.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000053672.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000107413; ENSMUSP00000103036; ENSMUSG00000047824.
GeneIDi68911.
KEGGimmu:68911.
UCSCiuc008pzp.1. mouse.

Organism-specific databases

CTDi90780.
MGIiMGI:1916161. Pygo2.

Phylogenomic databases

eggNOGiNOG72798.
GeneTreeiENSGT00530000063948.
HOGENOMiHOG000001580.
HOVERGENiHBG053774.
TreeFamiTF333020.

Enzyme and pathway databases

ReactomeiREACT_216539. formation of the beta-catenin:TCF transactivating complex.
REACT_219771. deactivation of the beta-catenin transactivating complex.

Miscellaneous databases

ChiTaRSiPygo2. mouse.
NextBioi328163.
SOURCEiSearch...

Gene expression databases

GenevestigatoriQ3V113.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00628. PHD. 1 hit.
[Graphical view]
SMARTiSM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS01359. ZF_PHD_1. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ3V113_MOUSE
AccessioniPrimary (citable) accession number: Q3V113
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: February 4, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.