Q3V0C5 (UBP48_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ubiquitin carboxyl-terminal hydrolase 48
EC=3.4.19.12

Alternative name(s):
Deubiquitinating enzyme 48
Ubiquitin thioesterase 48
Ubiquitin-specific-processing protease 48

Gene names

Name:	Usp48
Synonyms:	Kiaa4202

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1052 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites By similarity.
Catalytic activity	Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Subunit structure	Interacts with TRAF2 and RELA By similarity.
Subcellular location	Cytoplasm By similarity. Nucleus By similarity.
Sequence similarities	Belongs to the peptidase C19 family. Contains 3 DUSP domains. Contains 1 ubiquitin-like domain.
Sequence caution	The sequence AAH21769.1 differs from that shown. Reason: Frameshift at position 377. The sequence BAD90375.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Ubl conjugation pathway
Cellular component	Cytoplasm Nucleus
Coding sequence diversity	Alternative splicing
Domain	Repeat
Molecular function	Hydrolase Protease Thiol protease
PTM	Acetylation Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	mitochondrion Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	cysteine-type peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW ubiquitin thiolesterase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 5 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q3V0C5-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q3V0C5-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MVGPCPFGRRRRRRRRPPGSASATSVKAM

Note: No experimental confirmation available.

Isoform 3 (identifier: Q3V0C5-3)

The sequence of this isoform differs from the canonical sequence as follows:
     390-390: L → LA
     483-484: EP → GL
     485-1052: Missing.

Isoform 4 (identifier: Q3V0C5-4)

The sequence of this isoform differs from the canonical sequence as follows:
     483-484: EP → GL
     485-1052: Missing.

Isoform 5 (identifier: Q3V0C5-5)

The sequence of this isoform differs from the canonical sequence as follows:
     390-390: L → LA

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1052	1052	Ubiquitin carboxyl-terminal hydrolase 48		PRO_0000249524
Regions
	Domain	459 – 553	95	DUSP 1
	Domain	568 – 691	124	DUSP 2
	Domain	710 – 841	132	DUSP 3
	Domain	946 – 1026	81	Ubiquitin-like
Sites
	Active site	98	1	Nucleophile By similarity
	Active site	353	1	Proton acceptor By similarity
Amino acid modifications
	Modified residue	903	1	Phosphoserine By similarity
	Modified residue	904	1	Phosphoserine Ref.4
	Modified residue	905	1	Phosphoserine Ref.4
	Modified residue	973	1	N6-acetyllysine By similarity
Natural variations
	Alternative sequence	1	1	M → MVGPCPFGRRRRRRRRPPGS ASATSVKAM in isoform 2.		VSP_020482
	Alternative sequence	390	1	L → LA in isoform 3 and isoform 5.		VSP_020483
	Alternative sequence	483 – 484	2	EP → GL in isoform 3 and isoform 4.		VSP_020484
	Alternative sequence	485 – 1052	568	Missing in isoform 3 and isoform 4.		VSP_020485

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified September 19, 2006. Version 2. Checksum: 347520CB80F34303	FASTA	1,052	120,631
	10 20 30 40 50 60 MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCRG NPNCLVGIGE 70 80 90 100 110 120 HIWLGEIDEN SFHSIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 130 140 150 160 170 180 PSTCSDYTKG DGIHGGKDYE PQTICEHLQY LFALLQNSNR RYIDPSGFVK ALGLDTGQQQ 190 200 210 220 230 240 DAQEFSKLFM SLLEDTLSKQ KNPDVRNVVQ QQFCGEYAYV TVCNQCGRES KLVSKFYELE 250 260 270 280 290 300 LNIQGHKQLT DCISEFLKEE RLEGDNRYFC ENCQSKQNAT RKIRLLSLPC TLNLQLMRFV 310 320 330 340 350 360 FDRQTGHKKK LNAYIGFSES LDMEPYVEHK GGSFVYELSA VLIHRGVSAY SGHYIAHVKD 370 380 390 400 410 420 PQSGEWYKFN DEDIEKMEGK KLQLGIEEDL EPSKSQTRKP KCGKGTHCSR NAYMLVYRLQ 430 440 450 460 470 480 AQEKNHTMVQ VPAFLQELVD RDNSKFEEWC VEMAEMRKQS VDKGKAKHEE VKELYQRLPA 490 500 510 520 530 540 GAEPYEFVSL EWLQKWLDES TPTKPIDNNA CLCSHDKLHP DKISIMKRIS EYAANIFYSR 550 560 570 580 590 600 YGGGPRLTVK ALCKDCVVER CRVLRLKNQL NEDYKAVNNL LKSTMKGDGF WVGKSSLRSW 610 620 630 640 650 660 RQLALEQLDE QDGEAEQSNG KINGSTFNKD ESKEEKKEEE EELNFNEDIL CPHGELSISE 670 680 690 700 710 720 NERRLVSQEA WSKLQQYFPK APEFPSYREC CSQCKILERE GEENEALHKM IANEQKTSLP 730 740 750 760 770 780 NLFQDKNRPC LSNWPEDTDA LYIVSHFFLD EWRKFVRKPA RSAPVSSIGN AALLCPHGGL 790 800 810 820 830 840 MFTFPSLTKE DSKLCQPLER REGGWPTAAH NNIALIWPSE WQMIQKLFVV DKVIKITRIE 850 860 870 880 890 900 VGDVNPSQTQ YISEPSLCPD CREGLLCQQQ RDLREYTQAT IYVHKVVDNK KVMKDSAPEL 910 920 930 940 950 960 NVSSSETEED KEEAKPDGEK DPDFNQSNGS TKRQKTSQQG YVAYQKQVIR RSTRHRKVRG 970 980 990 1000 1010 1020 EKALLVSANQ TLKELKIQIM HAFSVAPFDQ NLSIDGKILN DDCATLGTLG VIPESVILLK 1030 1040 1050 ADEPIADYAA MDDVMQVCMP EEGFKGTGLL GH
	Isoform 2 [UniParc]. Checksum: 0449068D6093A9CD	FASTA	1,080	123,723
	10 20 30 40 50 60 MVGPCPFGRR RRRRRRPPGS ASATSVKAMA PRLQLEKAAW RWAETVRPEE VSQEHIETAY 70 80 90 100 110 120 RIWLEPCIRG VCRRNCRGNP NCLVGIGEHI WLGEIDENSF HSIDDPNCER RKKNSFVGLT 130 140 150 160 170 180 NLGATCYVNT FLQVWFLNLE LRQALYLCPS TCSDYTKGDG IHGGKDYEPQ TICEHLQYLF 190 200 210 220 230 240 ALLQNSNRRY IDPSGFVKAL GLDTGQQQDA QEFSKLFMSL LEDTLSKQKN PDVRNVVQQQ 250 260 270 280 290 300 FCGEYAYVTV CNQCGRESKL VSKFYELELN IQGHKQLTDC ISEFLKEERL EGDNRYFCEN 310 320 330 340 350 360 CQSKQNATRK IRLLSLPCTL NLQLMRFVFD RQTGHKKKLN AYIGFSESLD MEPYVEHKGG 370 380 390 400 410 420 SFVYELSAVL IHRGVSAYSG HYIAHVKDPQ SGEWYKFNDE DIEKMEGKKL QLGIEEDLEP 430 440 450 460 470 480 SKSQTRKPKC GKGTHCSRNA YMLVYRLQAQ EKNHTMVQVP AFLQELVDRD NSKFEEWCVE 490 500 510 520 530 540 MAEMRKQSVD KGKAKHEEVK ELYQRLPAGA EPYEFVSLEW LQKWLDESTP TKPIDNNACL 550 560 570 580 590 600 CSHDKLHPDK ISIMKRISEY AANIFYSRYG GGPRLTVKAL CKDCVVERCR VLRLKNQLNE 610 620 630 640 650 660 DYKAVNNLLK STMKGDGFWV GKSSLRSWRQ LALEQLDEQD GEAEQSNGKI NGSTFNKDES 670 680 690 700 710 720 KEEKKEEEEE LNFNEDILCP HGELSISENE RRLVSQEAWS KLQQYFPKAP EFPSYRECCS 730 740 750 760 770 780 QCKILEREGE ENEALHKMIA NEQKTSLPNL FQDKNRPCLS NWPEDTDALY IVSHFFLDEW 790 800 810 820 830 840 RKFVRKPARS APVSSIGNAA LLCPHGGLMF TFPSLTKEDS KLCQPLERRE GGWPTAAHNN 850 860 870 880 890 900 IALIWPSEWQ MIQKLFVVDK VIKITRIEVG DVNPSQTQYI SEPSLCPDCR EGLLCQQQRD 910 920 930 940 950 960 LREYTQATIY VHKVVDNKKV MKDSAPELNV SSSETEEDKE EAKPDGEKDP DFNQSNGSTK 970 980 990 1000 1010 1020 RQKTSQQGYV AYQKQVIRRS TRHRKVRGEK ALLVSANQTL KELKIQIMHA FSVAPFDQNL 1030 1040 1050 1060 1070 1080 SIDGKILNDD CATLGTLGVI PESVILLKAD EPIADYAAMD DVMQVCMPEE GFKGTGLLGH
	Isoform 3 [UniParc]. Checksum: 558437C9A7A809FE	FASTA	485	55,956
	10 20 30 40 50 60 MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCRG NPNCLVGIGE 70 80 90 100 110 120 HIWLGEIDEN SFHSIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 130 140 150 160 170 180 PSTCSDYTKG DGIHGGKDYE PQTICEHLQY LFALLQNSNR RYIDPSGFVK ALGLDTGQQQ 190 200 210 220 230 240 DAQEFSKLFM SLLEDTLSKQ KNPDVRNVVQ QQFCGEYAYV TVCNQCGRES KLVSKFYELE 250 260 270 280 290 300 LNIQGHKQLT DCISEFLKEE RLEGDNRYFC ENCQSKQNAT RKIRLLSLPC TLNLQLMRFV 310 320 330 340 350 360 FDRQTGHKKK LNAYIGFSES LDMEPYVEHK GGSFVYELSA VLIHRGVSAY SGHYIAHVKD 370 380 390 400 410 420 PQSGEWYKFN DEDIEKMEGK KLQLGIEEDL AEPSKSQTRK PKCGKGTHCS RNAYMLVYRL 430 440 450 460 470 480 QAQEKNHTMV QVPAFLQELV DRDNSKFEEW CVEMAEMRKQ SVDKGKAKHE EVKELYQRLP AGAGL
	Isoform 4 [UniParc]. Checksum: 8ACBDF6704499F90	FASTA	484	55,884
	10 20 30 40 50 60 MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCRG NPNCLVGIGE 70 80 90 100 110 120 HIWLGEIDEN SFHSIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 130 140 150 160 170 180 PSTCSDYTKG DGIHGGKDYE PQTICEHLQY LFALLQNSNR RYIDPSGFVK ALGLDTGQQQ 190 200 210 220 230 240 DAQEFSKLFM SLLEDTLSKQ KNPDVRNVVQ QQFCGEYAYV TVCNQCGRES KLVSKFYELE 250 260 270 280 290 300 LNIQGHKQLT DCISEFLKEE RLEGDNRYFC ENCQSKQNAT RKIRLLSLPC TLNLQLMRFV 310 320 330 340 350 360 FDRQTGHKKK LNAYIGFSES LDMEPYVEHK GGSFVYELSA VLIHRGVSAY SGHYIAHVKD 370 380 390 400 410 420 PQSGEWYKFN DEDIEKMEGK KLQLGIEEDL EPSKSQTRKP KCGKGTHCSR NAYMLVYRLQ 430 440 450 460 470 480 AQEKNHTMVQ VPAFLQELVD RDNSKFEEWC VEMAEMRKQS VDKGKAKHEE VKELYQRLPA GAGL
	Isoform 5 [UniParc]. Checksum: 503A45728DEE622D	FASTA	1,053	120,702
	10 20 30 40 50 60 MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCRG NPNCLVGIGE 70 80 90 100 110 120 HIWLGEIDEN SFHSIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 130 140 150 160 170 180 PSTCSDYTKG DGIHGGKDYE PQTICEHLQY LFALLQNSNR RYIDPSGFVK ALGLDTGQQQ 190 200 210 220 230 240 DAQEFSKLFM SLLEDTLSKQ KNPDVRNVVQ QQFCGEYAYV TVCNQCGRES KLVSKFYELE 250 260 270 280 290 300 LNIQGHKQLT DCISEFLKEE RLEGDNRYFC ENCQSKQNAT RKIRLLSLPC TLNLQLMRFV 310 320 330 340 350 360 FDRQTGHKKK LNAYIGFSES LDMEPYVEHK GGSFVYELSA VLIHRGVSAY SGHYIAHVKD 370 380 390 400 410 420 PQSGEWYKFN DEDIEKMEGK KLQLGIEEDL AEPSKSQTRK PKCGKGTHCS RNAYMLVYRL 430 440 450 460 470 480 QAQEKNHTMV QVPAFLQELV DRDNSKFEEW CVEMAEMRKQ SVDKGKAKHE EVKELYQRLP 490 500 510 520 530 540 AGAEPYEFVS LEWLQKWLDE STPTKPIDNN ACLCSHDKLH PDKISIMKRI SEYAANIFYS 550 560 570 580 590 600 RYGGGPRLTV KALCKDCVVE RCRVLRLKNQ LNEDYKAVNN LLKSTMKGDG FWVGKSSLRS 610 620 630 640 650 660 WRQLALEQLD EQDGEAEQSN GKINGSTFNK DESKEEKKEE EEELNFNEDI LCPHGELSIS 670 680 690 700 710 720 ENERRLVSQE AWSKLQQYFP KAPEFPSYRE CCSQCKILER EGEENEALHK MIANEQKTSL 730 740 750 760 770 780 PNLFQDKNRP CLSNWPEDTD ALYIVSHFFL DEWRKFVRKP ARSAPVSSIG NAALLCPHGG 790 800 810 820 830 840 LMFTFPSLTK EDSKLCQPLE RREGGWPTAA HNNIALIWPS EWQMIQKLFV VDKVIKITRI 850 860 870 880 890 900 EVGDVNPSQT QYISEPSLCP DCREGLLCQQ QRDLREYTQA TIYVHKVVDN KKVMKDSAPE 910 920 930 940 950 960 LNVSSSETEE DKEEAKPDGE KDPDFNQSNG STKRQKTSQQ GYVAYQKQVI RRSTRHRKVR 970 980 990 1000 1010 1020 GEKALLVSAN QTLKELKIQI MHAFSVAPFD QNLSIDGKIL NDDCATLGTL GVIPESVILL 1030 1040 1050 KADEPIADYA AMDDVMQVCM PEEGFKGTGL LGH

References

[1]	"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R.F., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H. Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4). Tissue: Embryonic tail.
[2]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3). Strain: C57BL/6J. Tissue: Lung and Testis.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-633 (ISOFORM 5). Strain: FVB/N. Tissue: Mammary tumor.
[4]	"Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry." Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M. J. Proteome Res. 7:5314-5326(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-904 AND SER-905, MASS SPECTROMETRY. Tissue: Melanoma.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK220190 mRNA. Translation: BAD90375.1. Different initiation. AK133251 mRNA. Translation: BAE21579.1. AK166158 mRNA. Translation: BAE38603.1. BC021769 mRNA. Translation: AAH21769.1. Frameshift.
IPI	IPI00458122. IPI00647978. IPI00649325. IPI00788354. IPI00788425.
RefSeq	NP_570949.2. NM_130879.2.
UniGene	Mm.218478.
3D structure databases
HSSP	HSSP built from PDB template 2AYN based on UniProtKB P54578.
ProteinModelPortal	Q3V0C5.
SMR	Q3V0C5. Positions 83-417, 960-1021.
ModBase	Search...
Protein family/group databases
MEROPS	C19.068.
PTM databases
PhosphoSite	Q3V0C5.
Proteomic databases
PaxDb	Q3V0C5.
PRIDE	Q3V0C5.
Protocols and materials databases
DNASU	170707.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000055131; ENSMUSP00000055016; ENSMUSG00000043411.
GeneID	170707.
KEGG	mmu:170707.
UCSC	uc008vjh.1. mouse. uc008vji.1. mouse. uc008vjj.1. mouse.
Organism-specific databases
CTD	84196.
MGI	MGI:2158502. Usp48.
Rouge	Search...
Phylogenomic databases
eggNOG	COG5077.
GeneTree	ENSGT00630000089581.
HOGENOM	HOG000231639.
HOVERGEN	HBG080368.
KO	K11858.
OMA	LSNWPED.
OrthoDB	EOG4GF3DC.
Gene expression databases
ArrayExpress	Q3V0C5.
Bgee	Q3V0C5.
CleanEx	MM_USP48.
Genevestigator	Q3V0C5.
GermOnline	ENSMUSG00000043411. Mus musculus.
Family and domain databases
InterPro	IPR006615. Pept_C19_DUSP. IPR018200. Pept_C19ubi-hydrolase_C_CS. IPR001394. Peptidase_C19. IPR019955. Ubiquitin_supergroup. [Graphical view]
Pfam	PF00443. UCH. 1 hit. [Graphical view]
PROSITE	PS51283. DUSP. 3 hits. PS00299. UBIQUITIN_1. False negative. PS50053. UBIQUITIN_2. 1 hit. PS00972. UCH_2_1. False negative. PS00973. UCH_2_2. 1 hit. PS50235. UCH_2_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	USP48. mouse.
NextBio	370218.
SOURCE	Search...

Entry information

Entry name

UBP48_MOUSE

Accession

Primary (citable) accession number: Q3V0C5
Secondary accession number(s): Q3TM39, Q571J9, Q8VDJ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 19, 2006
Last sequence update:	September 19, 2006
Last modified:	May 1, 2013
This is version 68 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program