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Protein

Growth factor

Gene

Tdgf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionGrowth factorUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Growth factorUniRule annotation
Gene namesi
Name:Tdgf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98658 Tdgf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500423041526 – 171Growth factorSequence analysisAdd BLAST146

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi81 ↔ 90PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Expressioni

Gene expression databases

GenevisibleiQ3UZP8 MM

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 91EGF-likeInterPro annotationAdd BLAST25

Sequence similaritiesi

Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.UniRule annotation

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1217 Eukaryota
ENOG410XP6K LUCA
HOVERGENiHBG054705

Family and domain databases

InterProiView protein in InterPro
IPR017047 Cripto_growth_factor
IPR019011 Cryptic/Cripto_CFC-dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
PANTHERiPTHR14949:SF26 PTHR14949:SF26, 1 hit
PfamiView protein in Pfam
PF09443 CFC, 1 hit
PIRSFiPIRSF036301 Cripto_growth_factor, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 1 hit
PS50026 EGF_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q3UZP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGYFSSSVVL LVAISSAFEF GPVAGRDLAI RDNSIWDQKE PAVRDRSFQF
60 70 80 90 100
VPSVGIQNSK SLNKTCCLNG GTCILGSFCA CPPSFYGRNC EHDVRKEHCG
110 120 130 140 150
SILHGTWLPK KCSLCRCWHG QLHCLPQTFL PGCDGQVMDQ DLKASGTPCQ
160 170
TPSVTTTFML AGACLFLDMK V
Length:171
Mass (Da):18,646
Last modified:October 11, 2005 - v1
Checksum:iC53400FDEEBF6380
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK133730 mRNA Translation: BAE21807.1
RefSeqiNP_035692.2, NM_011562.2
UniGeneiMm.5090

Genome annotation databases

GeneIDi21667
KEGGimmu:21667

Similar proteinsi

Entry informationi

Entry nameiQ3UZP8_MOUSE
AccessioniPrimary (citable) accession number: Q3UZP8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: June 20, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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