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Q3UYZ0

- Q3UYZ0_MOUSE

UniProt

Q3UYZ0 - Q3UYZ0_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Fzd3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. PDZ domain binding Source: RefGenome
    2. protein binding Source: MGI
    3. Wnt-activated receptor activity Source: RefGenome
    4. Wnt-protein binding Source: RefGenome

    GO - Biological processi

    1. canonical Wnt signaling pathway Source: RefGenome
    2. cell proliferation in midbrain Source: MGI
    3. commissural neuron axon guidance Source: MGI
    4. establishment of planar polarity Source: MGI
    5. facial nucleus development Source: RefGenome
    6. gonad development Source: RefGenome
    7. G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger Source: RefGenome
    8. inner ear morphogenesis Source: MGI
    9. midbrain development Source: MGI
    10. neural tube closure Source: MGI
    11. neuron migration Source: MGI
    12. post-anal tail morphogenesis Source: MGI
    13. regulation of transcription from RNA polymerase II promoter Source: RefGenome
    14. vasculature development Source: RefGenome

    Keywords - Molecular functioni

    Developmental proteinSAAS annotation, ReceptorSAAS annotation

    Protein family/group databases

    MEROPSiI93.001.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Fzd3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:108476. Fzd3.

    Subcellular locationi

    GO - Cellular componenti

    1. apical part of cell Source: MGI
    2. apical plasma membrane Source: MGI
    3. cytoplasm Source: RefGenome
    4. lateral plasma membrane Source: MGI
    5. neuron projection membrane Source: RefGenome
    6. plasma membrane Source: MGI

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ3UYZ0.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000115325.

    Family & Domainsi

    Sequence similaritiesi

    Contains FZ (frizzled) domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG006977.
    InParanoidiQ3UYZ0.

    Family and domain databases

    Gene3Di1.10.2000.10. 1 hit.
    InterProiIPR000539. Frizzled.
    IPR015526. Frizzled/SFRP.
    IPR020067. Frizzled_dom.
    IPR026553. FZD3_vertebrates.
    IPR017981. GPCR_2-like.
    [Graphical view]
    PANTHERiPTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF22. PTHR11309:SF22. 1 hit.
    PfamiPF01534. Frizzled. 1 hit.
    PF01392. Fz. 1 hit.
    [Graphical view]
    PRINTSiPR00489. FRIZZLED.
    SMARTiSM00063. FRI. 1 hit.
    [Graphical view]
    SUPFAMiSSF63501. SSF63501. 1 hit.
    PROSITEiPS50038. FZ. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q3UYZ0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVSWIVFDL WLLTVFLGQI GGHSLFSCEP ITLRMCQDLP YNTTFMPNLL    50
    NHYDQQTAAL AMEPFHPMVN LDCSRDFRPF LCALYAPICM EYGRVTLPCR 100
    RLCQRAYSEC SKLMEMFGVP WPEDMECSRF PDCDEPYPRL VDLNLVGDPT 150
    EGAPVAVQRD YGFWCPRELK IDPDLGYSFL HVRDCSPPCP NMYFRREELS 200
    FARYFIGLIS IICLSATLFT FLTFLIDVTR FRYPERPIIF YAVCYMMVSL 250
    IFFIGFLLED RVACNASSPA QYKASTVTQG YHNKACTMLF MVLYFFTMAG 300
    SVWWVILTIT WFLAAVPKWG SEAIEKKALL FHASAWGIPG TLTIILLAMN 350
    KIEGDNI 357
    Length:357
    Mass (Da):41,013
    Last modified:October 11, 2005 - v1
    Checksum:i17698D0E53EE0B2C
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei357 – 3571Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK134261 mRNA. Translation: BAE22071.1.
    UniGeneiMm.214687.
    Mm.404299.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK134261 mRNA. Translation: BAE22071.1 .
    UniGenei Mm.214687.
    Mm.404299.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000115325.

    Protein family/group databases

    MEROPSi I93.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:108476. Fzd3.

    Phylogenomic databases

    HOVERGENi HBG006977.
    InParanoidi Q3UYZ0.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q3UYZ0.

    Family and domain databases

    Gene3Di 1.10.2000.10. 1 hit.
    InterProi IPR000539. Frizzled.
    IPR015526. Frizzled/SFRP.
    IPR020067. Frizzled_dom.
    IPR026553. FZD3_vertebrates.
    IPR017981. GPCR_2-like.
    [Graphical view ]
    PANTHERi PTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF22. PTHR11309:SF22. 1 hit.
    Pfami PF01534. Frizzled. 1 hit.
    PF01392. Fz. 1 hit.
    [Graphical view ]
    PRINTSi PR00489. FRIZZLED.
    SMARTi SM00063. FRI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF63501. SSF63501. 1 hit.
    PROSITEi PS50038. FZ. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ForelimbImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ForelimbImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ForelimbImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ForelimbImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ForelimbImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ForelimbImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ForelimbImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: ForelimbImported.

    Entry informationi

    Entry nameiQ3UYZ0_MOUSE
    AccessioniPrimary (citable) accession number: Q3UYZ0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 11, 2005
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)