Unreviewed, UniProtKB/TrEMBL Q3UYN6 (Q3UYN6_MOUSE)

Names and origin

Protein names

Submitted name:
    Putative uncharacterized protein EMBL BAE22176.1

Gene names

Name:

Cacna1b MGI 88296

Organism

Mus musculus (Mouse) EMBL BAE22176.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	1134 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Membrane
Domain	Transmembrane RuleBase RU003378V0
Molecular function	Ionic channel RuleBase RU003378V0
Gene Ontology (GO)
Biological process	calcium ion transport Inferred from mutant phenotype. Source: MGI locomotory behavior Inferred from mutant phenotype. Source: MGI neurotransmitter secretion Inferred from mutant phenotype. Source: MGI positive regulation of neurotransmitter secretion Inferred from electronic annotation. Source: Compara regulation of blood pressure Inferred from mutant phenotype. Source: MGI regulation of heart contraction Inferred from mutant phenotype. Source: MGI response to ethanol Inferred from electronic annotation. Source: Compara response to organic cyclic substance Inferred from electronic annotation. Source: Compara response to testosterone stimulus Inferred from electronic annotation. Source: Compara transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	cell soma Inferred from direct assay. Source: MGI dendritic shaft Inferred from electronic annotation. Source: Compara nerve terminal Inferred from electronic annotation. Source: Compara synaptosome Inferred from electronic annotation. Source: Compara voltage-gated calcium channel complex Inferred from direct assay. Source: MGI
Molecular function	protein binding Inferred from physical interaction. Source: MGI voltage-gated calcium channel activity Inferred from mutant phenotype. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAE22176.1

Sequences

	Sequence		Length	Mass (Da)
	Q3UYN6-1 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 5F2CC37490DBC52C	FASTA	1,134	127,216
	10 20 30 40 50 60 LGLLLHPGAY FRDLWNILDF IVVSGALVAF AFSSFMGGSK GKDINTIKSL RVLRVLRPLK 70 80 90 100 110 120 TIKRLPKLKA VFDCVVNSLK NVLNILIVYM LFMFIFAVIA VQLFKGKFFY CTDESKELER 130 140 150 160 170 180 DCRGQYLDYE KEEVEAQPRQ WKKYDFHYDN VLWALLTLFT VSTGEGWPMV LKHSVDATYE 190 200 210 220 230 240 EQGPSPGFRM ELSIFYVVYF VVFPFFFVNI FVALIIITFQ EQGDKVMSEC SLEKNERACI 250 260 270 280 290 300 DFAISAKPLT RYMPQNKQSF QYKTWTFVVS PPFEYFIMAM IALNTVVLMM KFYDAPYEYE 310 320 330 340 350 360 LMLKCLNIVF TSMFSMECIL KIIAFGVLNY FRDAWNVFDF VTVLGSITDI LVTEIANNFI 370 380 390 400 410 420 NLSFLRLFRA ARLIKLLRQG YTIRILLWTF VQSFKALPYV CLLIAMLFFI YAIIGMQVFG 430 440 450 460 470 480 NIALDDDTSI NRHNNFRTFL QALMLLFRSA TGEAWHEIML SCLGNRACDP HANASECGSD 490 500 510 520 530 540 FAYFYFVSFI FLCSFLMLNL FVAVIMDNFE YLTRDSSILG PHHLDEFIRV WAEYDPAACG 550 560 570 580 590 600 RISYNDMFEM LKHMSPPLGL GKKCPARVAY KRLVRMNMPI SNEDMTVHFT STLMALIRTA 610 620 630 640 650 660 LEIKLAPAGT KQHQCDAELR KEISSVWANL PQKTLDLLVP PHKPDEMTVG KVYAALMIFD 670 680 690 700 710 720 FYKQNKTTRD QTHQAPGGLS QMGPVSLFHP LKATLEQTQP AVLRGARVFL RQKSATSLSN 730 740 750 760 770 780 GGAIQTQESG IKESLSWGTQ RTQDALYEAR APLERGHSAE IPVGQSGTLA VDVQMQNMTL 790 800 810 820 830 840 RGPNGEPQPG LESQGRAASM PRLAAETQPA PNASPMKRSI STLAPRPHGT QLCSTVLDRP 850 860 870 880 890 900 PPSQASHHHH HRCHRRRDKK QRSLEKGPSL SVDPEGAPST AAGPGLPHGE GSTACRRDRK 910 920 930 940 950 960 QERGRSQERR QPSSSSSEKQ RFYSCDRFGS REPPQLMPSL SSHPTSPTAA LEPAPHPQGS 970 980 990 1000 1010 1020 GSVNGSPLMS TSGASTPGRG GRRQLPQTPL TPRPSITYKT ANSSPVHFAE GQSGLPAFSP 1030 1040 1050 1060 1070 1080 GRLSRGLSEH NALLQKEPLS QPLAPGSRIG SDPYLGQRLD SEASAHTLPE DTLTFEEAVA 1090 1100 1110 1120 1130 TNSGRSSRTS YVSSLTSQSH PLRRVPNGYH CTLGLSTGVR ARHSYHHTDQ DHWC

References

[1]

"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J EMBL BAE22176.1. Tissue: Medulla oblongata EMBL BAE22176.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK134542 mRNA. Translation: BAE22176.1.
IPI	IPI00115062.
UniGene	Mm.4424
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q3UYN6.
Genome annotation databases
Ensembl	ENSMUST00000041342; ENSMUSP00000037416; ENSMUSG00000004113; Mus musculus. [Genome view] ENSMUST00000093372; ENSMUSP00000091064; ENSMUSG00000004113; Mus musculus. [Genome view] ENSMUST00000114447; ENSMUSP00000110090; ENSMUSG00000004113; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:88296. Cacna1b.
Phylogenomic databases
HOGENOM	HBG713873.
HOVERGEN	Q3UYN6.
InParanoid	Q3UYN6.
Gene expression databases
ArrayExpress	Q3UYN6.
Bgee	Q3UYN6.
Genevestigator	Q3UYN6.
Family and domain databases
InterPro	IPR018249. EF_HAND_2. IPR005821. Ion_trans. IPR014873. VDCC_a1su_IQ. IPR005447. VDCC_N_a1su. [Graphical view]
PANTHER	PTHR10037:SF58. NVDCCAlpha1. 1 hit.
Pfam	PF08763. Ca_chan_IQ. 1 hit. PF00520. Ion_trans. 2 hits. [Graphical view]
PROSITE	PS50222. EF_HAND_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q3UYN6_MOUSE

Accession

Primary (citable) accession number: Q3UYN6

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	January 19, 2010
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)