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Protein

Amino acid transporter

Gene

Slc1a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSymportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Amino acid transporterUniRule annotation
Gene namesi
Name:Slc1a2Imported
ORF Names:mCG_9657Imported, RP23-163L4.1-001Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:101931 Slc1a2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei45 – 67HelicalUniRule annotationAdd BLAST23
Transmembranei88 – 108HelicalUniRule annotationAdd BLAST21
Transmembranei120 – 142HelicalUniRule annotationAdd BLAST23
Transmembranei238 – 255HelicalUniRule annotationAdd BLAST18
Transmembranei275 – 300HelicalUniRule annotationAdd BLAST26
Transmembranei312 – 338HelicalUniRule annotationAdd BLAST27
Transmembranei344 – 367HelicalUniRule annotationAdd BLAST24
Transmembranei432 – 456HelicalUniRule annotationAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiQ3UYK6
PeptideAtlasiQ3UYK6
PRIDEiQ3UYK6

Expressioni

Gene expression databases

BgeeiENSMUSG00000005089
ExpressionAtlasiQ3UYK6 baseline and differential

Family & Domainsi

Sequence similaritiesi

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG3787 Eukaryota
COG1301 LUCA
HOVERGENiHBG000080
KOiK05613
OMAiVDWFMGI
OrthoDBiEOG091G0UCE

Family and domain databases

Gene3Di1.10.3860.10, 2 hits
InterProiView protein in InterPro
IPR001991 Na-dicarboxylate_symporter
IPR018107 Na-dicarboxylate_symporter_CS
IPR036458 Na:dicarbo_symporter_sf
PfamiView protein in Pfam
PF00375 SDF, 1 hit
SUPFAMiSSF118215 SSF118215, 2 hits
PROSITEiView protein in PROSITE
PS00713 NA_DICARBOXYL_SYMP_1, 1 hit
PS00714 NA_DICARBOXYL_SYMP_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3UYK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTEGANNM PKQVEVRMHD SHLSSDEPKH RNLGMRMCDK LGKNLLLSLT
60 70 80 90 100
VFGVILGAVC GGLLRLASPI HPDVVMLIAF PGDILMRMLK MLILPLIISS
110 120 130 140 150
LITGLSGLDA KASGRLGTRA MVYYMSTTII AAVLGVILVL AIHPGNPKLK
160 170 180 190 200
KQLGPGKKND EVSSLDAFLD LIRNLFPENL VQACFQQIQT VTKKVLVAPP
210 220 230 240 250
SEEANTTKAV ISMLNETMNE APEETKIVIK KGLEFKDGMN VLGLIGFFIA
260 270 280 290 300
FGIAMGKMGE QAKLMVEFFN ILNEIVMKLV IMIMWYSPLG IACLICGKII
310 320 330 340 350
AIKDLEVVAR QLGMYMITVI VGLIIHGGIF LPLIYFVVTR KNPFSFFAGI
360 370 380 390 400
FQAWITALGT ASSAGTLPVT FRCLEDNLGI DKRVTRFVLP VGATINMDGT
410 420 430 440 450
ALYEAVAAIF IAQMNGVILD GGQIVTVSLT ATLASIGAAS IPSAGLVTML
460 470 480 490 500
LILTAVGLPT EDISLLVAVD WLLDRMRTSV NVVGDSFGAG IVYHLSKSEL
510 520 530 540 550
DTIDSQHRMQ EDIEMTKTQS IYDDKNHRES NSNQCVYAAH NSVVIDECKV
560 570
TLAANGKSAD CSVEEEPWKR EK
Length:572
Mass (Da):62,030
Last modified:October 11, 2005 - v1
Checksum:i13C7C30DED40CA81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK134609 mRNA Translation: BAE22206.1
AL844605, AL844155 Genomic DNA Translation: CAM27623.1
CH466519 Genomic DNA Translation: EDL27674.1
RefSeqiNP_001070982.1, NM_001077514.3
NP_001070983.1, NM_001077515.2
UniGeneiMm.267547
Mm.453107
Mm.453110

Genome annotation databases

GeneIDi20511
KEGGimmu:20511

Similar proteinsi

Entry informationi

Entry nameiQ3UYK6_MOUSE
AccessioniPrimary (citable) accession number: Q3UYK6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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