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Protein
Submitted name:

Putative uncharacterized protein

Gene

Kl

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. fibroblast growth factor binding Source: MGI
  2. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro
  3. signal transducer activity Source: InterPro

GO - Biological processi

  1. acute inflammatory response Source: Ensembl
  2. aging Source: MGI
  3. calcium ion homeostasis Source: MGI
  4. carbohydrate metabolic process Source: InterPro
  5. energy reserve metabolic process Source: MGI
  6. insulin receptor signaling pathway Source: InterPro
  7. positive regulation of bone mineralization Source: MGI
  8. positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:KlImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1101771. Kl.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: MGI
  2. extracellular space Source: InterPro
  3. extracellular vesicular exosome Source: MGI
  4. integral component of membrane Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ3UYK1.
ExpressionAtlasiQ3UYK1. baseline and differential.
GenevestigatoriQ3UYK1.

Structurei

3D structure databases

ProteinModelPortaliQ3UYK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG053101.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR028546. Klotho.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PTHR10353:SF10. PTHR10353:SF10. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q3UYK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NHTVLHFYRC MISELVHANI TPVVALWQPA APHQGLPHAL AKHGAWENPH
60 70 80 90 100
TALAFADYAN LCFKELGHWV NLWITMNEPN TRNMTYRAGH HLLRAHALAW
110 120 130 140 150
HLYDDKFRAA QKGKISIALQ ADWIEPACPF SQNDKEVAER VLEFDIGWLA
160 170 180 190 200
EPIFGSGDYP RVMRDWLNQK NNFLLPYFTE DEKKLVRGSF DFLAVSHYTT
210 220 230 240 250
ILVDWEKEDP MKYNDYLEVQ EMTDITWLNS PSQVAVVPWG LRKVLNWLRF
260 270 280 290 300
KYGDLPMYVT ANGIDDDPHA EQDSLRIYYI KNYVNEALKA YVLDDINLCG
310 320 330 340 350
YFAYSLSDRS APKSGFYRYA ANQFEPKPSM KHYRKIIDSN GFLGSGTLGR
360 370 380 390 400
FCPEEYTVCT ECGFFQTRKS LLVFISFLVF TFIISLALIF HYSKKGQRSY

K
Length:401
Mass (Da):46,502
Last modified:October 11, 2005 - v1
Checksum:i4AC98F5C1D0807E7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK134616 mRNA. Translation: BAE22211.1.
UniGeneiMm.6500.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK134616 mRNA. Translation: BAE22211.1.
UniGeneiMm.6500.

3D structure databases

ProteinModelPortaliQ3UYK1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1101771. Kl.

Phylogenomic databases

HOVERGENiHBG053101.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiQ3UYK1.
ExpressionAtlasiQ3UYK1. baseline and differential.
GenevestigatoriQ3UYK1.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR028546. Klotho.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PTHR10353:SF10. PTHR10353:SF10. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Medulla oblongataImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Medulla oblongataImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Medulla oblongataImported.
  4. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Medulla oblongataImported.
  5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Medulla oblongataImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Medulla oblongataImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Medulla oblongataImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Medulla oblongataImported.

Entry informationi

Entry nameiQ3UYK1_MOUSE
AccessioniPrimary (citable) accession number: Q3UYK1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: February 4, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.