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Protein
Submitted name:

Melanin-concentrating hormone receptor 1

Gene

Mchr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Enzyme and pathway databases

ReactomeiR-MMU-375276. Peptide ligand-binding receptors.
R-MMU-416476. G alpha (q) signalling events.
R-MMU-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
Melanin-concentrating hormone receptor 1Imported
Gene namesi
Name:Mchr1Imported
Synonyms:Gpr24Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:2180756. Mchr1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 65HelicalSequence analysisAdd BLAST25
Transmembranei80 – 100HelicalSequence analysisAdd BLAST21
Transmembranei159 – 182HelicalSequence analysisAdd BLAST24
Transmembranei205 – 229HelicalSequence analysisAdd BLAST25
Transmembranei254 – 272HelicalSequence analysisAdd BLAST19
Transmembranei292 – 314HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000050164.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000126191.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 311G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST255

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118797.
HOVERGENiHBG105726.
KOiK04320.
OMAiITPVWLY.
OrthoDBiEOG091G0HEN.
TreeFamiTF315737.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR004047. MCH1_rcpt.
IPR008361. MCH_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01507. MCH1RECEPTOR.
PR01783. MCHRECEPTOR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3UY93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLQASLLST GPNASNISDG QDNFTLAGPP PRTRSVSYIN IIMPSVFGTI
60 70 80 90 100
CLLGIVGNST VIFAVVKKSK LHWCSNVPDI FIINLSVVDL LFLLGMPFMI
110 120 130 140 150
HQLMGNGVWH FGETMCTLIT AMDANSQFTS TYILTAMAID RYLATVHPIS
160 170 180 190 200
STKFRKPSMA TLVICLLWAL SFISITPVWL YARLIPFPGG AVGCGIRLPN
210 220 230 240 250
PDTDLYWFTL YQFFLAFALP FVVITAAYVK ILQRMTSSVA PASQRSIRLR
260 270 280 290 300
TKRVTRTAIA ICLVFFVCWA PYYVLQLTQL SISRPTLTFV YLYNAAISLG
310 320 330 340 350
YANSCLNPFV YIVLCETFRK RLVLSVKPAA QGQLRTVSNA QTADEERTES

KGT
Length:353
Mass (Da):39,120
Last modified:October 11, 2005 - v1
Checksum:iD85D186EB1A4AEF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102334 Genomic DNA. No translation available.
BC128286 mRNA. Translation: AAI28287.1.
AK134867 mRNA. Translation: BAE22319.1.
RefSeqiNP_660114.1. NM_145132.2.
UniGeneiMm.323523.

Genome annotation databases

EnsembliENSMUST00000166855; ENSMUSP00000126191; ENSMUSG00000050164.
GeneIDi207911.
KEGGimmu:207911.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102334 Genomic DNA. No translation available.
BC128286 mRNA. Translation: AAI28287.1.
AK134867 mRNA. Translation: BAE22319.1.
RefSeqiNP_660114.1. NM_145132.2.
UniGeneiMm.323523.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000126191.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000166855; ENSMUSP00000126191; ENSMUSG00000050164.
GeneIDi207911.
KEGGimmu:207911.

Organism-specific databases

CTDi2847.
MGIiMGI:2180756. Mchr1.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118797.
HOVERGENiHBG105726.
KOiK04320.
OMAiITPVWLY.
OrthoDBiEOG091G0HEN.
TreeFamiTF315737.

Enzyme and pathway databases

ReactomeiR-MMU-375276. Peptide ligand-binding receptors.
R-MMU-416476. G alpha (q) signalling events.
R-MMU-418594. G alpha (i) signalling events.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000050164.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR004047. MCH1_rcpt.
IPR008361. MCH_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01507. MCH1RECEPTOR.
PR01783. MCHRECEPTOR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3UY93_MOUSE
AccessioniPrimary (citable) accession number: Q3UY93
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.