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Protein

Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog

Gene

Fdxacb1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog
Short name:
FDX-ACDB domain-containing protein 1
Gene namesi
Name:Fdxacb1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:3584513. Fdxacb1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 622622Ferredoxin-fold anticodon-binding domain-containing protein 1 homologPRO_0000325957Add
BLAST

Proteomic databases

MaxQBiQ3UY23.
PaxDbiQ3UY23.
PRIDEiQ3UY23.

PTM databases

iPTMnetiQ3UY23.
PhosphoSiteiQ3UY23.

Expressioni

Gene expression databases

BgeeiENSMUSG00000037845.
CleanExiMM_D630004A14RIK.
ExpressionAtlasiQ3UY23. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037082.

Structurei

3D structure databases

ProteinModelPortaliQ3UY23.
SMRiQ3UY23. Positions 487-598.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini529 – 62294FDX-ACBPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 FDX-ACB domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2783. Eukaryota.
KOG4174. Eukaryota.
ENOG41108X7. LUCA.
GeneTreeiENSGT00530000063467.
HOGENOMiHOG000112565.
HOVERGENiHBG069342.
InParanoidiQ3UY23.
OMAiRFQHPKT.
OrthoDBiEOG091G01ZZ.
PhylomeDBiQ3UY23.
TreeFamiTF329685.

Family and domain databases

Gene3Di3.30.70.380. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR019446. DUF2431.
IPR005121. PheS_beta_Fdx_antiC-bd.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF10354. DUF2431. 1 hit.
PF03147. FDX-ACB. 1 hit.
[Graphical view]
SMARTiSM00896. FDX-ACB. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
SSF54991. SSF54991. 1 hit.
PROSITEiPS51447. FDX_ACB. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q3UY23-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLPRRLLLVG EGNFSFAASL IDGLDPSVSV TATGFQHRAA LEGDPVALEN
60 70 80 90 100
LKRLRERGVE VRFGVDCTQL SHALPADDRD FDRIYFNFPH CGRKAGVAKN
110 120 130 140 150
RELLAKFFQS CADVLAKAGE VHVTLCRGQG GTPADKPQRE WHNSWQVVAM
160 170 180 190 200
AALGGFILSD VCPFSCEAVP GYKCTGYRSQ DRPFHIEGAL TYIFTQSLPF
210 220 230 240 250
ESCQPRTFRV RLEDRWFYFT EPEALPGKLN RRFLEASSCH PIRTINEKLI
260 270 280 290 300
AELGKTFPLK RLKCPLPLLS RGGPSVFLPA TCDLLPTFWI RLHEDNSCSE
310 320 330 340 350
FQNGEITQEM EEIPVSVSEC TLPESPVRDG CKGAQEGICG RVKLGLRPSL
360 370 380 390 400
LVHVEAVIHS PDFLPASLHV LSGPVFRKCH ILPFMMPAFH ETLFILGFDN
410 420 430 440 450
NMKESCLPSL LGHLKDALGN LLTQTLQEGS SLGTSVEFVL QPNGKDYIIH
460 470 480 490 500
VKSLNFGPDC AENLIIGSIL TSKIVKHKHQ CFVFVSINLD LLVMLAYGIS
510 520 530 540 550
DWRILWTFDN RFLKRFAPGK IEHFKSYSLY PPCYVHDVSF WVDEKKAFDE
560 570 580 590 600
LEFHTVARAV SQDTVVSVQY RDRFQHPETR QVSLCYRLTY QTCDKALTPQ
610 620
LAAAMQSQFR KEIQRQLHVS PR
Length:622
Mass (Da):70,120
Last modified:March 18, 2008 - v2
Checksum:i538DC5F029757D8F
GO
Isoform 2 (identifier: Q3UY23-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-149: Missing.
     178-230: Missing.

Note: No experimental confirmation available.
Show »
Length:420
Mass (Da):47,334
Checksum:i370CC7FFCA5CBF39
GO
Isoform 3 (identifier: Q3UY23-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-309: Missing.

Show »
Length:313
Mass (Da):35,488
Checksum:i9F65251315D3476D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti506 – 5061W → R in BAE22390 (PubMed:16141072).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 309309Missing in isoform 3. 2 PublicationsVSP_032499Add
BLAST
Alternative sequencei1 – 149149Missing in isoform 2. 1 PublicationVSP_032500Add
BLAST
Alternative sequencei178 – 23053Missing in isoform 2. 1 PublicationVSP_032501Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK035237 mRNA. Translation: BAC28994.1.
AK085276 mRNA. Translation: BAC39409.1.
AK135025 mRNA. Translation: BAE22390.1.
BC116264 mRNA. Translation: AAI16265.1.
BC116265 mRNA. Translation: AAI16266.1.
CCDSiCCDS23174.1. [Q3UY23-1]
RefSeqiNP_941077.2. NM_198675.2. [Q3UY23-1]
UniGeneiMm.390169.

Genome annotation databases

EnsembliENSMUST00000042391; ENSMUSP00000037082; ENSMUSG00000037845. [Q3UY23-1]
ENSMUST00000176335; ENSMUSP00000135658; ENSMUSG00000037845. [Q3UY23-2]
GeneIDi382137.
KEGGimmu:382137.
UCSCiuc009pkq.1. mouse. [Q3UY23-1]
uc009pks.1. mouse. [Q3UY23-2]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK035237 mRNA. Translation: BAC28994.1.
AK085276 mRNA. Translation: BAC39409.1.
AK135025 mRNA. Translation: BAE22390.1.
BC116264 mRNA. Translation: AAI16265.1.
BC116265 mRNA. Translation: AAI16266.1.
CCDSiCCDS23174.1. [Q3UY23-1]
RefSeqiNP_941077.2. NM_198675.2. [Q3UY23-1]
UniGeneiMm.390169.

3D structure databases

ProteinModelPortaliQ3UY23.
SMRiQ3UY23. Positions 487-598.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037082.

PTM databases

iPTMnetiQ3UY23.
PhosphoSiteiQ3UY23.

Proteomic databases

MaxQBiQ3UY23.
PaxDbiQ3UY23.
PRIDEiQ3UY23.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042391; ENSMUSP00000037082; ENSMUSG00000037845. [Q3UY23-1]
ENSMUST00000176335; ENSMUSP00000135658; ENSMUSG00000037845. [Q3UY23-2]
GeneIDi382137.
KEGGimmu:382137.
UCSCiuc009pkq.1. mouse. [Q3UY23-1]
uc009pks.1. mouse. [Q3UY23-2]

Organism-specific databases

CTDi91893.
MGIiMGI:3584513. Fdxacb1.

Phylogenomic databases

eggNOGiKOG2783. Eukaryota.
KOG4174. Eukaryota.
ENOG41108X7. LUCA.
GeneTreeiENSGT00530000063467.
HOGENOMiHOG000112565.
HOVERGENiHBG069342.
InParanoidiQ3UY23.
OMAiRFQHPKT.
OrthoDBiEOG091G01ZZ.
PhylomeDBiQ3UY23.
TreeFamiTF329685.

Miscellaneous databases

PROiQ3UY23.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000037845.
CleanExiMM_D630004A14RIK.
ExpressionAtlasiQ3UY23. baseline and differential.

Family and domain databases

Gene3Di3.30.70.380. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR019446. DUF2431.
IPR005121. PheS_beta_Fdx_antiC-bd.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF10354. DUF2431. 1 hit.
PF03147. FDX-ACB. 1 hit.
[Graphical view]
SMARTiSM00896. FDX-ACB. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
SSF54991. SSF54991. 1 hit.
PROSITEiPS51447. FDX_ACB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFDXA1_MOUSE
AccessioniPrimary (citable) accession number: Q3UY23
Secondary accession number(s): Q14B93, Q8BUG6, Q8BZH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: September 7, 2016
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.