Unreviewed, UniProtKB/TrEMBL Q3UXV4 (Q3UXV4_MOUSE)

Names and origin

Protein names

Recommended name:
    Serine/threonine-protein phosphatase RuleBase RU004273V0
    EC=3.1.3.16 RuleBase RU004273V0

Gene names

Name:

Ppp3cb MGI 107163

Organism

Mus musculus (Mouse) EMBL BAE22459.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate. RuleBase RU004273V0
Sequence similarities	Belongs to the PPP phosphatase family.

Ontologies

Keywords
Ligand	Iron RuleBase RU004273V0
Molecular function	Hydrolase Spearmint SPM006186 RuleBase RU004273V0
Gene Ontology (GO)
Biological process	T cell differentiation Inferred from mutant phenotype. Source: MGI T cell homeostasis Inferred from mutant phenotype. Source: MGI heart development Inferred from mutant phenotype. Source: MGI muscle homeostasis Inferred from electronic annotation. Source: Compara negative regulation of T cell mediated cytotoxicity Inferred from mutant phenotype. Source: MGI protein amino acid dephosphorylation Inferred from mutant phenotype. Source: MGI regulation of gene expression Inferred from mutant phenotype. Source: MGI response to amphetamine Inferred from electronic annotation. Source: Compara response to cytokine stimulus Inferred from mutant phenotype. Source: MGI
Cellular component	insoluble fraction Inferred from electronic annotation. Source: Compara soluble fraction Inferred from electronic annotation. Source: Compara
Molecular function	calcium-dependent protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: Compara iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein heterodimerization activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q3UXV4-1 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: 400A2BC70FF78751	FASTA	452	51,446
	10 20 30 40 50 60 MDGIPRVDVL KNHLVKEGRV DEEIALRIIN EGAAILRREK TMIEVEAPIT VCGDIHGQFF 70 80 90 100 110 120 DLMKLFEVGG SPANTRYLFL GDYVDRGYFS IECVLYLWVL KILYPSTLFL LRGNHECRHL 130 140 150 160 170 180 TEYFTFKQEC KIKYSERVYE ACMEAFDSLP LAALLNQQFL CVHGGLSPEI HTLDDIRRLY 190 200 210 220 230 240 RFKEPPAFGP MCDLLWSDPS EDFGNEKSQE HFSHNTVRGC SYFYNYPAVC EFLQNNNLLS 250 260 270 280 290 300 IIRAHEAQDA GYRMYRKSQT TGFPSLITIF SAPNYLDVYN NKAAVLKYEN NVMNIRQFNC 310 320 330 340 350 360 SPHPYWLPNF MDVFTWSLPF VGEKVTEMLV NVLSICSDDE LMTEGEDQFD VGSAAARKEI 370 380 390 400 410 420 IRNKIRAIGK MARVFSVLRE ESESVLTLKG LTPTGMLPSG VLAGGRQTLQ SGNDVMQLAV 430 440 450 PQMDWGTTHS FANNTHNACR ELLLLFSSCL SS

References

[1]

"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK135203 mRNA. Translation: BAE22459.1.
IPI	IPI00654325.
UniGene	Mm.274432
3D structure databases
SMR	Q3UXV4. Positions 2-336.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3UXV4.
Proteomic databases
PRIDE	Q3UXV4.
Genome annotation databases
Ensembl	ENSMUST00000022355; ENSMUSP00000022355; ENSMUSG00000021816; Mus musculus. [Genome view]
UCSC	uc007sjz.1. mouse.
Organism-specific databases
MGI	MGI:107163. Ppp3cb.
Phylogenomic databases
HOVERGEN	Q3UXV4.
InParanoid	Q3UXV4.
PhylomeDB	Q3UXV4.
Gene expression databases
ArrayExpress	Q3UXV4.
Bgee	Q3UXV4.
Genevestigator	Q3UXV4.
Family and domain databases
InterPro	IPR004843. M-pesterase. IPR006186. Ser/Thr-sp_prot-phosphatase. [Graphical view]
PANTHER	PTHR11668. T_phtase_apaH. 1 hit.
Pfam	PF00149. Metallophos. 1 hit. [Graphical view]
PRINTS	PR00114. STPHPHTASE.
SMART	SM00156. PP2Ac. 1 hit. [Graphical view]
PROSITE	PS00125. SER_THR_PHOSPHATASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q3UXV4_MOUSE

Accession

Primary (citable) accession number: Q3UXV4

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2005
Last sequence update:	October 11, 2005
Last modified:	February 9, 2010
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)