Q3UXV4 (Q3UXV4_MOUSE) Unreviewed, UniProtKB/TrEMBL
Last modified
May 29, 2013.
Version 62.
History...
Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Serine/threonine-protein phosphatase RuleBase RU004273 EC=3.1.3.16 RuleBase RU004273 | ||
| Gene names |
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| Organism | Mus musculus (Mouse) EMBL BAE22459.1 | ||
| Taxonomic identifier | 10090 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus![]() |
Protein attributes
| Sequence length | 452 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Catalytic activity | A phosphoprotein + H2O = a protein + phosphate. RuleBase RU004273 |
| Sequence similarities | Belongs to the PPP phosphatase family. RuleBase RU004273 |
Ontologies
| Keywords | |
|---|---|
| Ligand | Iron RuleBase RU004273 |
| Molecular function | Hydrolase RuleBase RU004273 |
| Gene Ontology (GO) | |
| Biological_process | T cell differentiation Inferred from mutant phenotype PubMed 12091710. Source: MGI T cell homeostasisInferred from mutant phenotype PubMed 18097009. Source: MGI heart developmentInferred from mutant phenotype PubMed 11904392. Source: MGI negative regulation of T cell mediated cytotoxicityInferred from mutant phenotype PubMed 18097009. Source: MGI protein dephosphorylationInferred from mutant phenotype PubMed 12091710. Source: MGI regulation of gene expressionInferred from mutant phenotype PubMed 18097009. Source: MGI response to cytokine stimulusInferred from mutant phenotype PubMed 18097009. Source: MGI |
| Molecular_function | protein serine/threonine phosphatase activity Inferred from direct assay PubMed 11904392PubMed 12091710. Source: MGI |
| Complete GO annotation... | |
Sequences
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References
| [1] | "High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1. |
| [2] | "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1. |
| [3] | "RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. Hayashizaki Y.Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1. |
| [4] | "Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1. |
| [5] | "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1. |
| [6] | Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. Hayashizaki Y.Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1. |
| [7] | "The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1. |
| [8] | "Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE22459.1. Tissue: Wolffian duct includes surrounding region EMBL BAE22459.1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AK135203 mRNA. Translation: BAE22459.1. |
| IPI | IPI00654325. |
| UniGene | Mm.274432. |
3D structure databases | |
| ProteinModelPortal | Q3UXV4. |
| SMR | Q3UXV4. Positions 2-336. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 10090.ENSMUSP00000022355. |
Proteomic databases | |
| PRIDE | Q3UXV4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Organism-specific databases | |
| MGI | MGI:107163. Ppp3cb. |
Phylogenomic databases | |
| HOGENOM | HOG000172699. |
| HOVERGEN | HBG002819. |
| InParanoid | Q3UXV4. |
Gene expression databases | |
| ArrayExpress | Q3UXV4. |
| Genevestigator | Q3UXV4. |
Family and domain databases | |
| InterPro | IPR004843. Metallo_PEstase_dom. IPR006186. Ser/Thr-sp_prot-phosphatase. [Graphical view] |
| Pfam | PF00149. Metallophos. 1 hit. [Graphical view] |
| PRINTS | PR00114. STPHPHTASE. |
| SMART | SM00156. PP2Ac. 1 hit. [Graphical view] |
| PROSITE | PS00125. SER_THR_PHOSPHATASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| ChiTaRS | PPP3CB. mouse. |
| SOURCE | Search... |
Entry information
| Entry name | Q3UXV4_MOUSE | ||||||||
| Accession | Primary (citable) accession number: Q3UXV4 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
