Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (P55)

Gene

Pik3r3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (P55)Imported
Gene namesi
Name:Pik3r3Imported
ORF Names:mCG_19660Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

PTM / Processingi

Proteomic databases

PRIDEiQ3UXE9

Expressioni

Gene expression databases

BgeeiENSMUSG00000028698
ExpressionAtlasiQ3UXE9 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ3UXE9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 160SH2InterPro annotationAdd BLAST96
Domaini358 – 452SH2InterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili181 – 208Sequence analysisAdd BLAST28
Coiled coili246 – 266Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4637 Eukaryota
ENOG410XP6R LUCA
HOVERGENiHBG082100
KOiK02649
OMAiQHCIIYE
OrthoDBiEOG091G0C3Z

Family and domain databases

CDDicd09930 SH2_cSH2_p85_like, 1 hit
cd09942 SH2_nSH2_p85_like, 1 hit
Gene3Di3.30.505.10, 2 hits
InterProiView protein in InterPro
IPR032498 PI3K_P85_iSH2
IPR035020 PI3kinase_P85_cSH2
IPR035022 PI3kinase_P85_nSH2
IPR001720 PI3kinase_P85_p55
IPR000980 SH2
IPR036860 SH2_dom_sf
PANTHERiPTHR10155 PTHR10155, 1 hit
PfamiView protein in Pfam
PF16454 PI3K_P85_iSH2, 1 hit
PF00017 SH2, 2 hits
PRINTSiPR00401 SH2DOMAIN
SMARTiView protein in SMART
SM00252 SH2, 2 hits
SUPFAMiSSF55550 SSF55550, 2 hits
PROSITEiView protein in PROSITE
PS50001 SH2, 2 hits

Sequencei

Sequence statusi: Complete.

Q3UXE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYNTVWSMDR DDADWREVMM PYSTELIFYI EMDPPALPPK PPKPMTPAVT
60 70 80 90 100
NGMKDSFISL QDAEWYWGDI SREEVNDKLR DMPDGTFLVR DASTKMQGDY
110 120 130 140 150
TLTLRKGGNN KLIKIYHRDG KYGFSEPLTF TSVVELINHY HHESLAQYNP
160 170 180 190 200
KLDVKLTYPV SRFQQDQLVK EDNIDAVGKN LQEFHSQYQE KSKEYDRLYE
210 220 230 240 250
EYTRTSQEIQ MKRTAIEAFN ETIKIFEEQC HTQEQHSKDY IERFRREGNE
260 270 280 290 300
KEIERIMMNY DKLKSRLGEI HDSKLRLEQD LKKQALDNRE IDKKMNSIKP
310 320 330 340 350
DLIQLRKIRD QHLVWLNHRG VRQRRLNAWL GIKNEDSDES YFINEEDENL
360 370 380 390 400
PHYDEKTWFV EDINRVQAED LLYGKPDGAF LIRESSKKGC YACSVVADGE
410 420 430 440 450
VKHCVIYSTA RGYGFAEPYN LYSSLKELVL HYQQTSLVQH NDSLNVRLAY
460
PVHAQMPTLC R
Length:461
Mass (Da):54,474
Last modified:October 11, 2005 - v1
Checksum:i97A01A0DFAAC661F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK132341 mRNA Translation: BAE21116.1
AK135693 mRNA Translation: BAE22614.1
CH466552 Genomic DNA Translation: EDL30611.1
RefSeqiNP_853616.1, NM_181585.5
XP_017175528.1, XM_017320039.1
XP_017175529.1, XM_017320040.1
UniGeneiMm.253819

Genome annotation databases

GeneIDi18710
KEGGimmu:18710

Similar proteinsi

Entry informationi

Entry nameiQ3UXE9_MOUSE
AccessioniPrimary (citable) accession number: Q3UXE9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2005
Last sequence update: October 11, 2005
Last modified: May 23, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health